(Q40663274)

22 September 2017

Poly(ADP-ribose) polymerase-1 is a positive regulator of the p53-mediated G1 arrest response following ionizing radiation (English)

1 reference

22 September 2017

Sonya Wieler

1

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22 September 2017

Jean-Philippe Gagné

2

1 reference

22 September 2017

Homayoun Vaziri

3

1 reference

22 September 2017

Guy G Poirier

4

1 reference

22 September 2017

Samuel Benchimol

5

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22 September 2017

language of work or name

English

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publication date

17 March 2003

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Journal of Biological Chemistry

22 September 2017

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22 September 2017

278

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22 September 2017

18914-18921

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22 September 2017

21

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p53, the cellular gatekeeper for growth and division

22 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

The complexity of p53 modulation: emerging patterns from divergent signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Definition of a consensus binding site for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Covalent and noncovalent modifiers of the p53 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Activation of the ATM kinase by ionizing radiation and phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Enhanced phosphorylation of p53 by ATM in response to DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

A role for ATR in the DNA damage-induced phosphorylation of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribosyl)ation reactions in the regulation of nuclear functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribose) polymerase-1: what have we learned from the deficient mouse model?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribose) binds to specific domains of p53 and alters its DNA binding functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

ADP-ribosylation of wild-type p53 in vitro: binding of p53 protein to specific p53 consensus sequence prevents its modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribosyl)ation of p53 in vitro and in vivo modulates binding to its DNA consensus sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Role of poly(ADP-ribose) polymerase in cell-cycle checkpoint mechanisms following gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribosyl)ation is required for p53-dependent signal transduction induced by radiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Cell cycle perturbations following DNA damage in the presence of ADP-ribosylation inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

DNA excision repair and DNA damage-induced apoptosis are linked to Poly(ADP-ribosyl)ation but have different requirements for p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Function of poly(ADP-ribose) polymerase in response to DNA damage: gene-disruption study in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Poly(ADP-ribose) polymerase null mouse cells synthesize ADP-ribose polymers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Identification of a minimal transforming domain of p53: negative dominance through abrogation of sequence-specific DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Analysis of genomic integrity and p53-dependent G1 checkpoint in telomerase-induced extended-life-span human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Influence of ionizing radiation on proliferation, c-myc expression and the induction of apoptotic cell death in two breast tumour cell lines differing in p53 status

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Dual function for poly(ADP-ribose) synthesis in response to DNA strand breakage

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Post-translational modification of poly(ADP-ribose) polymerase induced by DNA strand breaks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Histone shuttle driven by the automodification cycle of poly(ADP-ribose)polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Growth factor modulation of p53-mediated growth arrest versus apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes rapid induction of cell death upon overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

The 193-kD vault protein, VPARP, is a novel poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Suppression of G1 arrest and enhancement of G2 arrest by inhibitors of poly(ADP-ribose) polymerase: possible involvement of poly(ADP-ribosyl)ation in cell cycle arrest following gamma-irradiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

A cellular survival switch: poly(ADP-ribosyl)ation stimulates DNA repair and silences transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

Roles of poly(ADP-ribosyl)ation and PARP in apoptosis, DNA repair, genomic stability and functions of p53 and E2F-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M211641200

21 January 2018

Identifiers

DOI

10.1074/JBC.M211641200

1 reference

22 September 2017

1 reference