(Q40663632)

English

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells.

scientific article published on 14 March 2003

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

The cationic amphipathic alpha-helix of HIV-1 viral protein R (Vpr) binds to nucleic acids, permeabilizes membranes, and efficiently transfects cells (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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Emmanuel Coeytaux

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Dominique Coulaud

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Olivier Danos

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

Antoine Kichler

5

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1 November 2019

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14 March 2003

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1 November 2019

Journal of Biological Chemistry

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1 November 2019

278

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1 November 2019

20

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1 November 2019

18110-18116

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1 November 2019

Biochemical analyses of the interactions between human immunodeficiency virus type 1 Vpr and p6(Gag).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

HIV-1 Vpr enhances viral burden by facilitating infection of tissue macrophages but not nondividing CD4+ T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

HIV-1 Vpr increases viral expression by manipulation of the cell cycle: a mechanism for selection of Vpr in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

The HIV-1 virion-associated protein vpr is a coactivator of the human glucocorticoid receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

HIV-1 infection requires a functional integrase NLS.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Characterization of HIV-1 vpr nuclear import: analysis of signals and pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Viral protein R regulates nuclear import of the HIV-1 pre-integration complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Dynamic disruptions in nuclear envelope architecture and integrity induced by HIV-1 Vpr.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

NMR structure of the (52-96) C-terminal domain of the HIV-1 regulatory protein Vpr: molecular insights into its biological functions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

NMR structure of the (1-51) N-terminal domain of the HIV-1 regulatory protein Vpr

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Functional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Cellular and molecular barriers to gene transfer by a cationic lipid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Cell cycle dependence of gene transfer by lipoplex, polyplex and recombinant adenovirus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Direct binding to nucleic acids by Vpr of human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Efficient DNA transfection mediated by the C-terminal domain of human immunodeficiency virus type 1 viral protein R

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Binding of cationic alpha-helical peptides to plasmid DNA and their gene transfer abilities into cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Loss of binding and entry of liposome-DNA complexes decreases transfection efficiency in differentiated airway epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

DNA transfection mediated by cationic liposomes containing lipopolylysine: characterization and mechanism of action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Cell delivery, intracellular trafficking and expression of an integrin-mediated gene transfer vector in tracheal epithelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Cell receptors involved in adenovirus entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Extraction of cholesterol with methyl-beta-cyclodextrin perturbs formation of clathrin-coated endocytic vesicles

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Lipoplex-mediated transfection of mammalian cells occurs through the cholesterol-dependent clathrin-mediated pathway of endocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Hemolytic and antimicrobial activities of the twenty-four individual omission analogues of melittin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Effect of cholesterol and charge on pore formation in bilayer vesicles by a pH-sensitive peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

New basic membrane-destabilizing peptides for plasmid-based gene delivery in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Macropinocytosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

HIV-1 genome nuclear import is mediated by a central DNA flap

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Interactions of the C-terminus of viral protein R with nucleic acids are modulated by its N-terminus

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Differential effects of alpha-, beta- and gamma-cyclodextrins on human erythrocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Polylysine-based transfection systems utilizing receptor-mediated delivery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M300248200

21 January 2018

Identifiers

10.1074/JBC.M300248200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12639957%20AND%20SRC:MED&resulttype=core&format=json

1 November 2019

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