(Q40665959)

22 September 2017

title

Function of a genetically modified human liver cell line that stores, processes and secretes insulin (English)

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22 September 2017

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B E Tuch

1

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22 September 2017

B Szymanska

2

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22 September 2017

M Yao

3

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22 September 2017

M T Tabiin

4

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22 September 2017

D J Gross

5

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22 September 2017

S Holman

6

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22 September 2017

M Anne Swan

7

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22 September 2017

R K B Humphrey

8

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22 September 2017

G M Marshall

9

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22 September 2017

A M Simpson

10

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22 September 2017

publication date

1 March 2003

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22 September 2017

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22 September 2017

volume

10

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22 September 2017

issue

6

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22 September 2017

page(s)

490-503

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describes a project that uses

22 September 2017

HUH7-ins

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cites work

Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Gene therapy of diabetes: glucose-stimulated insulin secretion in a human hepatoma cell line (HEP G2ins/g).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Regulated expression of mature human insulin in the liver of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Remission in models of type 1 diabetes by gene therapy using a single-chain insulin analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Gene therapy for diabetes mellitus in rats by hepatic expression of insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Insulin degradation: mechanisms, products, and significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Endosomal proteolysis of internalized insulin at the C-terminal region of the B chain by cathepsin D

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Decreased apoptotic response of inclusion-cell disease fibroblasts: a consequence of lysosomal enzyme missorting?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Macro- and micro-domains in the endocrine pancreas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Markedly decreased oxygen tension in transplanted rat pancreatic islets irrespective of the implantation site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

The insulin factory: a tour of the plant surroundings and a visit to the assembly line. The Minkowski lecture 1973 revisited

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

IPF1/PDX1 deficiency and beta-cell dysfunction in Psammomys obesus, an animal With type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Intravenous infusion of diarginylinsulin, an insulin analogue: effects on glucose turnover and lipid levels in insulin-treated type II diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Engineering of glucose-stimulated insulin secretion and biosynthesis in non-islet cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Glucose-induced Proinsulin Biosynthesis Role of Islet Cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Human liver glucokinase gene: cloning and sequence determination of two alternatively spliced cDNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Immunoelectron microscopy: a new method for detection of insulin antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

Recovery of human fetal pancreas after one year of implantation in the diabetic patient

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Regulated expression of human insulin in the liver of transgenic mice corrects diabetic alterations.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Control of Insulin Biosynthesis in the Human Fetal Beta Cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Transplantation of genetically engineered insulin-producing hepatocytes into immunoincompetent mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

The oval-shaped cell as a candidate for a liver stem cell in embryonic, neonatal and precancerous liver: identification based on morphology and immunohistochemical staining for albumin and pyruvate kinase isoenzyme expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Induction of hepatocytes in the pancreas of copper-depleted rats following copper repletion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Resistance of the human fetal beta-cell to the toxic effect of multiple low-dose streptozotocin.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Function, Mass, and Replication of Porcine and Rat Islets Transplanted into Diabetic Nude Mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Release of proinsulin from the human fetal β cell

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Improved preservation of ultrastructural morphology in human spermatozoa using betaine in the primary fixative

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3301911

7 January 2021

Identifiers

DOI

10.1038/SJ.GT.3301911

1 reference

Dimensions Publication ID

22 September 2017

1025308312

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1 reference