(Q40678267)

22 September 2017

title

The isolated N-terminal domain of the glucagon-like peptide-1 (GLP-1) receptor binds exendin peptides with much higher affinity than GLP-1. (English)

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22 September 2017

author name string

Rakel López de Maturana

1

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22 September 2017

Angela Willshaw

2

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22 September 2017

Antje Kuntzsch

3

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22 September 2017

Rainer Rudolph

4

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22 September 2017

Dan Donnelly

5

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22 September 2017

language of work or name

English

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publication date

10 January 2003

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

12

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22 September 2017

page(s)

10195-10200

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The glucagon-like peptides

22 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212147200

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Glucagon-like peptide-1 7-36: a physiological incretin in man.

21 January 2018

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Pancreatic beta-cells are rendered glucose-competent by the insulinotropic hormone glucagon-like peptide-1(7-37).

21 January 2018

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Effect of truncated glucagon-like peptide-1 [proglucagon-(78-107) amide] on endocrine secretion from pig pancreas, antrum, and nonantral stomach.

21 January 2018

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Comparison of the effects of glucagon-like peptide-1-(1-37) and -(7-37) and glucagon on islet hormone release from isolated perfused canine and rat pancreases

21 January 2018

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Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man.

21 January 2018

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A role for glucagon-like peptide-1 in the central regulation of feeding

21 January 2018

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Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

21 January 2018

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Insulinotropic hormone glucagon-like peptide-I(7-37) stimulation of proinsulin gene expression and proinsulin biosynthesis in insulinoma beta TC-1 cells

21 January 2018

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Antidiabetogenic effect of glucagon-like peptide-1 (7-36)amide in normal subjects and patients with diabetes mellitus

21 January 2018

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New drug targets for type 2 diabetes and the metabolic syndrome

21 January 2018

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Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor

21 January 2018

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Exendin-4 and glucagon-like-peptide-1: NMR structural comparisons in the solution and micelle-associated states

21 January 2018

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The glucagon-like peptide-1 receptor binding site for the N-terminus of GLP-1 requires polarity at Asp198 rather than negative charge

21 January 2018

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Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1

21 January 2018

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Functional and protein chemical characterization of the N-terminal domain of the rat corticotropin-releasing factor receptor 1

21 January 2018

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Expression, purification, and characterization of a soluble form of the first extracellular domain of the human type 1 corticotropin releasing factor receptor

21 January 2018

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In vitro folding, functional characterization, and disulfide pattern of the extracellular domain of human GLP-1 receptor

21 January 2018

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Characterization of glucagon-like peptide-1 receptor-binding determinants

21 January 2018

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A simple method for the determination of affinity and binding site concentration in receptor binding studies

21 January 2018

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The amino-terminal fragment of the adenylate cyclase activating polypeptide (PACAP) receptor functions as a high affinity PACAP binding domain.

21 January 2018

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The first extracellular domain of corticotropin releasing factor-R1 contains major binding determinants for urocortin and astressin

21 January 2018

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Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding

21 January 2018

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Identification of binding domains of the growth hormone-releasing hormone receptor by analysis of mutant and chimeric receptor proteins

21 January 2018

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Determinants for calcitonin analog interaction with the calcitonin receptor N-terminus and transmembrane-loop regions

21 January 2018

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Insulinotropic glucagonlike peptide-I(7-37)/(7-36)amide A new incretin hormone

21 January 2018

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High potency antagonists of the pancreatic glucagon-like peptide-1 receptor

21 January 2018

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The N-terminal fragment of human parathyroid hormone receptor 1 constitutes a hormone binding domain and reveals a distinct disulfide pattern

21 January 2018

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The isolated N-terminal extracellular domain of the glucagon-like peptide-1 (GLP)-1 receptor has intrinsic binding activity

21 January 2018

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Medium-dependence of the secondary structure of exendin-4 and glucagon-like-peptide-1

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M212147200

1 reference

22 September 2017

1 reference