(Q40680537)

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Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance

scientific article published on January 2003

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Europe PubMed Central

PubMed publication ID

22 September 2017

Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance (English)

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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Emma Månsson

1

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Emma Flordal

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Jan Liliemark

3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Tatiana Spasokoukotskaja

4

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Howard Elford

5

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Svetlana Lagercrantz

6

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Staffan Eriksson

7

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

Freidoun Albertioni

8

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Europe PubMed Central

PubMed publication ID

22 September 2017

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publication date

1 January 2003

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Europe PubMed Central

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22 September 2017

Biochemical Pharmacology

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Europe PubMed Central

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22 September 2017

65

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Europe PubMed Central

PubMed publication ID

22 September 2017

2

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

237-247

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

2-Chlorodeoxyadenosine treatment of low-grade lymphomas

1 reference

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Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs

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7 January 2021

Mammalian deoxyribonucleoside kinases

1 reference

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Mechanisms responsible for resistance of sublines derived from leukemia cell lines to an antitumor agent 9-beta-D-arabinofuranosyl-2-fluoroadenine

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7 January 2021

Ribonucleotide reductases

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Sequential hydroxyurea-cytarabine chemotherapy for refractory non-Hodgkin's lymphoma

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Inhibition of nucleoside diphosphate reductase by hydroxybenzohydroxamic acid derivatives

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Determination of 2-chloro-2'-deoxyadenosine nucleotides in leukemic cells by ion-pair high-performance liquid chromatography

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Simultaneous determination of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate and 3-deazauridine 5'-triphosphate in human leukemia cells by high-performance liquid chromatography

1 reference

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7 January 2021

Expression of deoxycytidine kinase and phosphorylation of 2-chlorodeoxyadenosine in human normal and tumour cells and tissues

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Regulation of Low Km (Ecto) 5’-Nucleotidase Gene Expression in Leukemic Cells

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Real-time quantitative PCR assays for deoxycytidine kinase, deoxyguanosine kinase and 5'-nucleotidase mRNA measurement in cell lines and in patients with leukemia

1 reference

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7 January 2021

Multidrug resistance gene (mdr1) RNA levels in relation to P-glycoprotein content of leukemic cells from patients with acute leukemia.

1 reference

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7 January 2021

The intracellular localization of deoxycytidine kinase

1 reference

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7 January 2021

Mitochondrial and submitochondrial localization of human deoxyguanosine kinase

1 reference

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Expression of an altered ribonucleotide reductase activity associated with the replication of murine cytomegalovirus in quiescent fibroblasts.

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A rapid assay for CDP reductase activity in mammalian cell extracts

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Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors

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7 January 2021

Chromosomal imbalances in diffuse large B-cell lymphoma detected by comparative genomic hybridization

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A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage

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7 January 2021

Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells

1 reference

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7 January 2021

Response to 2-chlorodeoxyadenosine in patients with B-cell chronic lymphocytic leukemia resistant to fludarabine

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7 January 2021

2-Chlorodeoxyadenosine in the treatment of relapsed/refractory chronic lymphoproliferative disorders

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Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine

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A phase I clinical trial of 2-chlorodeoxyadenosine in pediatric patients with acute leukemia

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7 January 2021

Metabolism and action of purine nucleoside analogs

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7 January 2021

Common resistance mechanisms to deoxynucleoside analogues in variants of the human erythroleukaemic line K562.

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7 January 2021

Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides.

1 reference

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7 January 2021

Expression of high Km 5'-nucleotidase in leukemic blasts is an independent prognostic factor in adults with acute myeloid leukemia

1 reference

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7 January 2021

Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance

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7 January 2021

Analysis of DNA methylation of the 5' region of the deoxycytidine kinase gene in CCRF-CEM-sensitive and cladribine (CdA)- and 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine (CAFdA)-resistant cells

1 reference

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7 January 2021

Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs

1 reference

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7 January 2021

Induction of an apoptotic program in cell-free extracts by 2-chloro-2'-deoxyadenosine 5'-triphosphate and cytochrome c

1 reference

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7 January 2021

Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release

1 reference

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7 January 2021

Identifiers

10.1016/S0006-2952(02)01484-3

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

22 September 2017

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