(Q40684016)

22 September 2017

title

Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis (English)

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22 September 2017

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Feng Chen

1

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22 September 2017

Roger Chang

2

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22 September 2017

Marcus Trivedi

3

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22 September 2017

Yassemi Capetanaki

4

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22 September 2017

Vincent L Cryns

5

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22 September 2017

language of work or name

English

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publication date

10 December 2002

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Journal of Biological Chemistry

22 September 2017

published in

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22 September 2017

volume

278

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22 September 2017

issue

9

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22 September 2017

page(s)

6848-6853

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22 September 2017

cites work

Caspases: enemies within

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212021200

Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M212021200

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin A

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Lamin proteolysis facilitates nuclear events during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Apoptosis generates stable fragments of human type I keratins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Effect of mutation and phosphorylation of type I keratins on their caspase-mediated degradation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Disruption of muscle architecture and myocardial degeneration in mice lacking desmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Desmin is essential for the tensile strength and integrity of myofibrils but not for myogenic commitment, differentiation, and fusion of skeletal muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Null mutation in the desmin gene gives rise to a cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Missense mutations in desmin associated with familial cardiac and skeletal myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

A dysfunctional desmin mutation in a patient with severe generalized myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Desmin myopathy, a skeletal myopathy with cardiomyopathy caused by mutations in the desmin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Desmin mutation responsible for idiopathic dilated cardiomyopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyte

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Coding sequence and growth regulation of the human vimentin gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Caspase-6 gene disruption reveals a requirement for lamin A cleavage in apoptotic chromatin condensation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Active caspases and cleaved cytokeratins are sequestered into cytoplasmic inclusions in TRAIL-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

DEDD regulates degradation of intermediate filaments during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Desmin/vimentin intermediate filaments are dispensable for many aspects of myogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Truncated desmin in PtK2 cells induces desmin-vimentin-cytokeratin coprecipitation, involution of intermediate filament networks, and nuclear fragmentation: a model for many degenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Desmin cytoskeleton linked to muscle mitochondrial distribution and respiratory function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Binding of two desmin derivatives to the plasma membrane and the nuclear envelope of avian erythrocytes: evidence for a conserved site-specificity in intermediate filament-membrane interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Cytoplasmic intermediate filaments are stably associated with nuclear matrices and potentially modulate their DNA-binding function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Keratin-dependent, epithelial resistance to tumor necrosis factor-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M212021200

21 January 2018

Identifiers

DOI

10.1074/JBC.M212021200

1 reference

22 September 2017

1 reference