(Q40700008)

22 September 2017

title

4-hydroxynonenal induces glutamate cysteine ligase through JNK in HBE1 cells (English)

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22 September 2017

7

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22 September 2017

Dale A Dickinson

1

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22 September 2017

Karen E Iles

2

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22 September 2017

Nobuo Watanabe

3

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22 September 2017

Takeo Iwamoto

4

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22 September 2017

Hongqiao Zhang

5

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22 September 2017

David M Krzywanski

6

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22 September 2017

publication date

1 October 2002

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Free Radical Biology and Medicine

22 September 2017

published in

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22 September 2017

volume

33

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22 September 2017

issue

7

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22 September 2017

page(s)

974

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Posttranscriptional Regulation ofMRP/GS-XPump and γ-Glutamylcysteine Synthetase Expression by 1-(4-Amino-2-methyl-5-pyrimidinyl) methyl-3- (2-chloroethyl)-3-nitrosourea and by Cycloheximide in Human Glioma Cells

22 September 2017

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7 January 2021

Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase

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7 January 2021

Transcriptional Regulation of γ-Glutamylcysteine Synthetase-Heavy Subunit by Oxidants in Human Alveolar Epithelial Cells

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7 January 2021

The induction of GSH synthesis by nanomolar concentrations of NO in endothelial cells: a role for γ-glutamylcysteine synthetase and γ-glutamyl transpeptidase

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7 January 2021

Increased gamma-glutamylcysteine synthetase and gamma-glutamyl transpeptidase activities enhance resistance of rat lung epithelial L2 cells to quinone toxicity

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7 January 2021

Inducible expression of the gamma-glutamylcysteine synthetase light subunit by t-butylhydroquinone in HepG2 cells is not dependent on an antioxidant-responsive element

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7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

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7 January 2021

Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells

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7 January 2021

4-Hydroxynonenal mimics ozone-induced modulation of macrophage function ex vivo

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7 January 2021

Oxygen radicals in ulcerative colitis

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7 January 2021

Release of aldehydes from rat alveolar macrophages exposed in vitro to low concentrations of nitrogen dioxide

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7 January 2021

Alpha,beta-unsaturated aldehydes increase glutathione S-transferase mRNA and protein: correlation with activation of the antioxidant response element

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7 January 2021

Accelerated metabolism and exclusion of 4-hydroxynonenal through induction of RLIP76 and hGST5.8 is an early adaptive response of cells to heat and oxidative stress

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7 January 2021

The hepatocellular metabolism of 4-hydroxynonenal by alcohol dehydrogenase, aldehyde dehydrogenase, and glutathione S-transferase

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7 January 2021

Formation and export of the glutathione conjugate of 4-hydroxy-2, 3-E-nonenal (4-HNE) in hepatoma cells

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7 January 2021

HNE interacts directly with JNK isoforms in human hepatic stellate cells

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7 January 2021

Regulation of rat hepatocyte protein kinase C ? isoenzymes by the lipid peroxidation product 4-hydroxy-2,3-nonenal: A signaling pathway to modulate vesicular transport of glycoproteins

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7 January 2021

Regulation of gamma-glutamylcysteine synthetase subunit gene expression: insights into transcriptional control of antioxidant defenses

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7 January 2021

Multi-faceted regulation of gamma-glutamylcysteine synthetase

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7 January 2021

Cell-type specific differences in glutamate cysteine ligase transcriptional regulation demonstrate independent subunit control

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7 January 2021

Biogenic 4‐hydroxy‐2‐nonenal activates transcription factor AP‐1 but not NF‐κB in cells of the macrophage lineage

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7 January 2021

Activation of stress signaling pathways by the end product of lipid peroxidation. 4-hydroxy-2-nonenal is a potential inducer of intracellular peroxide production

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7 January 2021

Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death

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7 January 2021

A549 subclones demonstrate heterogeneity in toxicological sensitivity and antioxidant profile

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7 January 2021

AP-1 activation through endogenous H(2)O(2) generation by alveolar macrophages

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7 January 2021

Papilloma virus immortalized tracheal epithelial cells retain a well-differentiated phenotype

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7 January 2021

High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivatives

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7 January 2021

Role of protein kinase C in basal and hydrogen peroxide-stimulated NF-kappa B activation in the murine macrophage J774A.1 cell line

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7 January 2021

Reduced activation of transcriptional factor AP-1 among peripheral blood T cells from elderly humans after PHA stimulation: restorative effect of phorbol diesters

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7 January 2021

Selectivity of antibodies to estrogen receptors α and β (ERα and ERβ) for detecting DNA-bound ERα and ERβ in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

4-Hydroxy-2-nonenal increases gamma-glutamylcysteine synthetase gene expression in alveolar epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Identification of a putative antioxidant response element in the 5'-flanking region of the human gamma-glutamylcysteine synthetase heavy subunit gene

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Cloning and analysis of the rat glutamate-cysteine ligase modifier subunit promoter

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

An electrophile responsive element (EpRE) regulates beta-naphthoflavone induction of the human gamma-glutamylcysteine synthetase regulatory subunit gene. Constitutive expression is mediated by an adjacent AP-1 site

1 reference

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7 January 2021

Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73

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7 January 2021

Activation of several MAP kinases upon stimulation of rat alveolar macrophages: role of the NADPH oxidase

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7 January 2021

Identification of 4-hydroxynonenal as a cytotoxic product originating from the peroxidation of liver microsomal lipids

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes

1 reference

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7 January 2021

4-Hydroxynonenal as a biological signal: molecular basis and pathophysiological implications

1 reference

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7 January 2021

The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons.

1 reference

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7 January 2021

Metabolism of 4-hydroxynonenal by rat Kupffer cells

1 reference

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7 January 2021

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

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7 January 2021

Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells

1 reference

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7 January 2021

The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Expression of glutathione and gamma-glutamylcysteine synthetase mRNA is Jun dependent

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Direct inhibition of c-Jun N-terminal kinase in sympathetic neurones prevents c-jun promoter activation and NGF withdrawal-induced death

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

NO2 reactive absorption substrates in rat pulmonary surface lining fluids.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Nitrogen dioxide depletes uric acid and ascorbic acid but not glutathione from lung lining fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

4-hydroxy-2,3-trans-nonenal induces transcription and expression of aldose reductase.

1 reference

https://api.crossref.org/works/10.1016%2FS0891-5849%2802%2900991-7

7 January 2021

10.1016/S0891-5849(02)00991-7

Identifiers

DOI

1 reference

22 September 2017

1 reference