(Q40701382)

English

Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.

scientific article published on 24 September 2002

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12324473%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12324473%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Ioannis Zaganas

1

1 reference

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3 December 2019

author name string

Cleanthe Spanaki

2

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3 December 2019

Michael Karpusas

3

1 reference

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3 December 2019

Andreas Plaitakis

4

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3 December 2019

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publication date

24 September 2002

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3 December 2019

Journal of Biological Chemistry

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3 December 2019

277

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3 December 2019

48

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3 December 2019

46552-46558

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3 December 2019

L-leucine and a nonmetabolized analogue activate pancreatic islet glutamate dehydrogenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Glial glutamate dehydrogenase: ultrastructural localization and regional distribution in relation to the mitochondrial enzyme, cytochrome oxidase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Nerve tissue-specific human glutamate dehydrogenase that is thermolabile and highly regulated by ADP.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

The structure of bovine glutamate dehydrogenase provides insights into the mechanism of allostery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

The structure of apo human glutamate dehydrogenase details subunit communication and allostery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Conformational flexibility in glutamate dehydrogenase. Role of water in substrate recognition and catalysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

The glial cell glutamate uptake carrier countertransports pH-changing anions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M208596200

21 January 2018

Identifiers

10.1074/JBC.M208596200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12324473%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12324473%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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