(Q40706812)

22 September 2017

title

Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function (English)

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22 September 2017

R Bruce Montgomery

1

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22 September 2017

language of work or name

English

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publication date

1 September 2002

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International Journal of Cancer

22 September 2017

published in

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22 September 2017

volume

101

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22 September 2017

issue

2

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22 September 2017

page(s)

111-117

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

22 September 2017

cites work

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Enhanced tumorigenic behavior of glioblastoma cells expressing a truncated epidermal growth factor receptor is mediated through the Ras-Shc-Grb2 pathway

21 January 2018

1 reference

Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

21 January 2018

1 reference

Growth factors and cancer

21 January 2018

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RETRACTED: 4,5-Dianilinophthalimide: a protein-tyrosine kinase inhibitor with selectivity for the epidermal growth factor receptor signal transduction pathway and potent in vivo antitumor activity

21 January 2018

1 reference

A specific inhibitor of the epidermal growth factor receptor tyrosine kinase

21 January 2018

1 reference

Tyrosine kinase inhibition: an approach to drug development

21 January 2018

1 reference

Differential modulation of mitogen-activated protein (MAP) kinase/extracellular signal-related kinase kinase and MAP kinase activities by a mutant epidermal growth factor receptor

21 January 2018

1 reference

Epidermal growth factor receptor stimulation of diacylglycerol kinase

21 January 2018

1 reference

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

21 January 2018

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

21 January 2018

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Activation of the Ras/mitogen-activated protein kinase pathway by kinase-defective epidermal growth factor receptors results in cell survival but not proliferation

21 January 2018

1 reference

An incomplete program of cellular tyrosine phosphorylations induced by kinase-defective epidermal growth factor receptors

21 January 2018

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A kinase-negative epidermal growth factor receptor that retains the capacity to stimulate DNA synthesis

21 January 2018

1 reference

Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

21 January 2018

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Unliganded epidermal growth factor receptor dimerization induced by direct interaction of quinazolines with the ATP binding site.

21 January 2018

1 reference

Suppression of invasion and MMP-9 expression in NIH 3T3 and v-H-Ras 3T3 fibroblasts by lovastatin through inhibition of ras isoprenylation

21 January 2018

1 reference

Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines.

21 January 2018

1 reference

BE-23372M, a novel and specific inhibitor for epidermal growth factor receptor kinase

21 January 2018

1 reference

Receptor blockade with monoclonal antibodies as anti-cancer therapy

21 January 2018

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Switching signals on or off by receptor dimerization

21 January 2018

1 reference

EGF induced SOS phosphorylation in PC12 cells involves P90 RSK-2

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/IJC.10560

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22 September 2017

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