(Q40723348)

23 September 2017

The neural cell adhesion molecule L1 potentiates integrin-dependent cell migration to extracellular matrix proteins (English)

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12 May 2020

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Karsten Thelen

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757736&resulttype=core&format=json

12 May 2020

Vishram Kedar

2

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12 May 2020

Anitha K Panicker

3

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12 May 2020

Ralf-Steffen Schmid

4

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12 May 2020

Bentley R Midkiff

5

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12 May 2020

Patricia F Maness

6

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12 May 2020

language of work or name

English

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publication date

1 June 2002

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23 September 2017

Journal of Neuroscience

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757736&resulttype=core&format=json

12 May 2020

volume

22

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12 May 2020

page(s)

4918-4931

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12 May 2020

issue

12

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L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellum.

12 May 2020

cites work

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12 December 2020

Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes

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12 December 2020

Immunolocalization of the neural cell adhesion molecule L1 in epithelia of rodents

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12 December 2020

Immunocytological localization of cell adhesion molecules L1 and N-CAM and the shared carbohydrate epitope L2 during development of the mouse neocortex.

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12 December 2020

Ectodomain shedding of L1 adhesion molecule promotes cell migration by autocrine binding to integrins

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12 December 2020

Neuronal production of fibronectin in the cerebral cortex during migration and layer formation is unique to specific cortical domains

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12 December 2020

Altered distribution of dopaminergic neurons in the brain of L1 null mice

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12 December 2020

The third fibronectin type III repeat is required for L1 to serve as an optimal substratum for neurite extension

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12 December 2020

Mode and tempo of tangential cell migration in the cerebellar external granular layer.

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12 December 2020

TAG-1 can mediate homophilic binding, but neurite outgrowth on TAG-1 requires an L1-like molecule and beta 1 integrins

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12 December 2020

A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration

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12 December 2020

Beta1-class integrins regulate the development of laminae and folia in the cerebral and cerebellar cortex

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12 December 2020

Molecular structure and functional testing of human L1CAM: an interspecies comparison

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12 December 2020

EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake.

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12 December 2020

Differential effects of two hydrocephalus/MASA syndrome-related mutations on the homophilic binding and neuritogenic activities of the cell adhesion molecule L1.

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12 December 2020

Integrin-mediated signals regulated by members of the rho family of GTPases

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12 December 2020

A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone.

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12 December 2020

Pathological missense mutations of neural cell adhesion molecule L1 affect homophilic and heterophilic binding activities.

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12 December 2020

Tenascin promotes cerebellar granule cell migration and neurite outgrowth by different domains in the fibronectin type III repeats

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12 December 2020

The L1 adhesion molecule is a cellular ligand for VLA-5

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12 December 2020

Functional cooperation of beta1-integrins and members of the Ig superfamily in neurite outgrowth induction

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12 December 2020

PC12 cells utilize the homophilic binding site of L1 for cell-cell adhesion but L1-alphavbeta3 interaction for neurite outgrowth

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12 December 2020

Ligation of CD31 (PECAM-1) on endothelial cells increases adhesive function of alphavbeta3 integrin and enhances beta1 integrin-mediated adhesion of eosinophils to endothelial cells

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12 December 2020

Regulation of signal transduction by endocytosis

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12 December 2020

Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis

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12 December 2020

A molecular mechanism of integrin crosstalk: alphavbeta3 suppression of calcium/calmodulin-dependent protein kinase II regulates alpha5beta1 function

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12 December 2020

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.

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12 December 2020

Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin

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12 December 2020

Reelin binds alpha3beta1 integrin and inhibits neuronal migration.

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12 December 2020

Plasmin-sensitive dibasic sequences in the third fibronectin-like domain of L1-cell adhesion molecule (CAM) facilitate homomultimerization and concomitant integrin recruitment

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12 December 2020

The role of endocytosis in regulating L1-mediated adhesion

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12 December 2020

Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization

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12 December 2020

A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis.

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12 December 2020

Neurite outgrowth on immobilized axonin-1 is mediated by a heterophilic interaction with L1(G4)

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12 December 2020

Fine mapping of inhibitory anti-alpha5 monoclonal antibody epitopes that differentially affect integrin-ligand binding.

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12 December 2020

Cytoplasmic domain mutations of the L1 cell adhesion molecule reduce L1-ankyrin interactions.

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12 December 2020

Experimental modification of postnatal cerebellar granule cell migration in vitro.

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12 December 2020

Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb

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12 December 2020

The integrin beta 1 subunit associates with the vitronectin receptor alpha v subunit to form a novel vitronectin receptor in a human embryonic kidney cell line

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12 December 2020

Src-mediated tyrosine phosphorylation of dynamin is required for beta2-adrenergic receptor internalization and mitogen-activated protein kinase signaling

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12 December 2020

Disease-associated mutations in L1 CAM interfere with ligand interactions and cell-surface expression

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12 December 2020

Abnormalities in neuronal process extension, hippocampal development, and the ventricular system of L1 knockout mice.

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12 December 2020

Structural analysis of the murine cell adhesion molecule L1 by electron microscopy and computer-assisted modelling

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12 December 2020

Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation

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12 December 2020

Neural cell recognition molecule L1: relating biological complexity to human disease mutations

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12 December 2020

L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to alpha v beta 3 integrin.

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12 December 2020

Moving membrane up to the front of migrating cells

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12 December 2020

The alphavbeta3 integrin regulates alpha5beta1-mediated cell migration toward fibronectin

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12 December 2020

The Arg-Gly-Asp motif in the cell adhesion molecule L1 promotes neurite outgrowth via interaction with the alphavbeta3 integrin

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12 December 2020

The nerve growth factor-inducible large external (NILE) glycoprotein and neural cell adhesion molecule (N-CAM) have distinct patterns of expression in the developing rat central nervous system

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12 December 2020

L1 makes immunological progress by expanding its relations

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12 December 2020

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

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12 December 2020

Distinct functions of alpha3 and alpha(v) integrin receptors in neuronal migration and laminar organization of the cerebral cortex.

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12 December 2020

CD9 of mouse brain is implicated in neurite outgrowth and cell migration in vitro and is associated with the alpha 6/beta 1 integrin and the neural adhesion molecule L1

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12 December 2020

Human neural cell adhesion molecule L1 and rat homologue NILE are ligands for integrin alpha v beta 3

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12 December 2020

Regulation of cell motility by mitogen-activated protein kinase

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12 December 2020

Role of neuron-glial junctional domain proteins in the maintenance and termination of neuronal migration across the embryonic cerebral wall.

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12 December 2020

Cell migration: a physically integrated molecular process

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12 December 2020

A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis

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12 December 2020

Disruption of the mouse L1 gene leads to malformations of the nervous system

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12 December 2020

L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns.

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12 December 2020

Expression of adhesion molecules and the establishment of boundaries during embryonic and neural development

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12 December 2020

The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway

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12 December 2020

Extracellular matrix molecules and their receptors: functions in neural development

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12 December 2020

Oriented endocytic recycling of alpha5beta1 in motile neutrophils

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12 December 2020

Deposition and role of thrombospondin in the histogenesis of the cerebellar cortex

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12 December 2020

Differential expression of cell adhesion molecules in variants of K1735 melanoma cells differing in metastatic capacity

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12 December 2020

Multiple receptor systems promote CNS neural migration.

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12 December 2020

Ankyrins and cellular targeting of diverse membrane proteins to physiological sites

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12 December 2020

Sequential expression and differential function of multiple adhesion molecules during the formation of cerebellar cortical layers

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12 December 2020

The neural cell adhesion molecule N-CAM enhances L1-dependent cell-cell interactions

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12 December 2020

Mutational analysis of the L1 neuronal cell adhesion molecule identifies membrane-proximal amino acids of the cytoplasmic domain that are required for cytoskeletal anchorage

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12 December 2020

The axonal recognition molecule F11 is a multifunctional protein: specific domains mediate interactions with Ng-CAM and restrictin

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12 December 2020

Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice

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12 December 2020

Superactivation of integrin alphavbeta3 by low antagonist concentrations

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12 December 2020

Expression and regulation of the neural cell adhesion molecule L1 on human cells of myelomonocytic and lymphoid origin

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12 December 2020

PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic

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12 December 2020

Variants of human L1 cell adhesion molecule arise through alternate splicing of RNA.

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12 December 2020

Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.

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12 December 2020

Synergistic activation of dynamin GTPase by Grb2 and phosphoinositides

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12 December 2020

Distinct modes of neuronal migration in different domains of developing cerebellar cortex.

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12 December 2020

The EGF receptor: a nexus for trafficking and signaling

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12 December 2020

Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells

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12 December 2020

Neuronal migration in cerebellar microcultures is inhibited by antibodies against a neurite outgrowth domain of laminin

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12 December 2020

Immunoelectron microscopic localization of the neural cell adhesion molecules L1 and N-CAM during postnatal development of the mouse cerebellum

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12 December 2020

A single immunoglobulin-like domain of the human neural cell adhesion molecule L1 supports adhesion by multiple vascular and platelet integrins

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12 December 2020

Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth.

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12 December 2020

10.1523/JNEUROSCI.22-12-04918.2002

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757736&resulttype=core&format=json

12 May 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6757736&resulttype=core&format=json

12 May 2020

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