(Q40726752)

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Mutagenesis and peptide analysis of the DRY motif in the alpha2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors.

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scholarly article

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9 November 2019

Mutagenesis and peptide analysis of the DRY motif in the alpha2A adrenergic receptor: evidence for alternate mechanisms in G protein-coupled receptors (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12054508%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

G protein-coupled receptor

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7

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9 November 2019

author name string

Duane A Chung

1

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9 November 2019

Susan M Wade

2

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9 November 2019

Carol B Fowler

3

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9 November 2019

Danielle D Woods

4

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9 November 2019

Paolo B Abada

5

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9 November 2019

Henry I Mosberg

6

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9 November 2019

publication date

1 May 2002

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9 November 2019

Biochemical and Biophysical Research Communications

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9 November 2019

293

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9 November 2019

4

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9 November 2019

1233-1241

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9 November 2019

Structure and function of G protein-coupled receptors

1 reference

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Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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How receptors talk to trimeric G proteins

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The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

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7 January 2021

The role of the aspartate-arginine-tyrosine triad in the m1 muscarinic receptor: mutations of aspartate 122 and tyrosine 124 decrease receptor expression but do not abolish signaling

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7 January 2021

Modulation of GDP release from transducin by the conserved Glu134-Arg135 sequence in rhodopsin

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The function of a highly-conserved arginine residue in activation of the muscarinic M1 receptor

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Crystal structure of rhodopsin: A G protein-coupled receptor

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Advances in Determination of a High-Resolution Three-Dimensional Structure of Rhodopsin, a Model of G-Protein-Coupled Receptors (GPCRs)

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The second intracellular loop of the m5 muscarinic receptor is the switch which enables G-protein coupling

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G(i) activator region of alpha(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation

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Inverse agonist activity at the alpha(2A)-adrenergic receptor.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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Secondary structure of bacteriorhodopsin fragments. External sequence constraints specify the conformation of transmembrane helices

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A self-consistent method for the analysis of protein secondary structure from circular dichroism.

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Rhodopsin arginine-135 mutants are phosphorylated by rhodopsin kinase and bind arrestin in the absence of 11-cis-retinal

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7 January 2021

Constitutive activation of opsin: influence of charge at position 134 and size at position 296.

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7 January 2021

Three cytoplasmic loops of rhodopsin interact with transducin

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7 January 2021

Multisite contacts involved in coupling of the beta-adrenergic receptor with the stimulatory guanine-nucleotide-binding regulatory protein. Structural and functional studies by beta-receptor-site-specific synthetic peptides

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7 January 2021

An alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptors

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Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis

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NMR structure of the second intracellular loop of the alpha 2A adrenergic receptor: evidence for a novel cytoplasmic helix

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7 January 2021

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7 January 2021

based on heuristic

inferred from DOI database lookup

Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine.

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7 January 2021

Identifiers

10.1016/S0006-291X(02)00357-1

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12054508%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12054508%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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