(Q40731680)

English

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions.

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Structure-activity relationships at human and rat A2B adenosine receptors of xanthine derivatives substituted at the 1-, 3-, 7-, and 8-positions (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Christa E Müller

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Kenneth A. Jacobson

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

author name string

Soon-Ai Kim

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Melissa A Marshall

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Neli Melman

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Hak Sung Kim

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Joel Linden

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

language of work or name

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publication date

1 May 2002

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Journal of Medicinal Chemistry

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

45

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

2131-2138

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

Effects of 8-phenyl and 8-cycloalkyl substituents on the activity of mono-, di-, and trisubstituted alkylxanthines with substitution at the 1-, 3-, and 7-positions

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of the triazolotriazine [3H]ZM 241385 as a radioligand at recombinant human A2B adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogs of caffeine: antagonists with selectivity for A2 adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Psychomotor-stimulant effects of 3-isobutyl-1-methylxanthine: comparison with caffeine and 7-(2-chloroethyl) theophylline.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine receptor activation induces vascular endothelial growth factor in human retinal endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8-Aryl-and 8-cycloalkyl-1,3-dipropylxanthines: further potent and selective antagonists for A1-adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subclasses of adenosine receptors in the central nervous system: Interaction with caffeine and related methylxanthines

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine receptor ligands: potential as therapeutic agents in asthma and COPD.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP and protein kinase A stimulate Cdc42: role of A(2) adenosine receptors in human mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Canine mast cell adenosine receptors: cloning and expression of the A3 receptor and evidence that degranulation is mediated by the A2B receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The A2b adenosine receptor mediates cAMP responses to adenosine receptor agonists in human intestinal epithelia

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogues of 1,3-dipropyl-8-phenylxanthine: enhancement of selectivity at A1-adenosine receptors by aryl substituents

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caffeine analogs: structure-activity relationships at adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

2-Alkynyl-8-aryl-9-methyladenines as novel adenosine receptor antagonists: their synthesis and structure-activity relationships toward hepatic glucose production induced via agonism of the A(2B) receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analogues of caffeine and theophylline: effect of structural alterations on affinity at adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A2A adenosine receptors from rat striatum and rat pheochromocytoma PC12 cells: characterization with radioligand binding and by activation of adenylate cyclase

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of adenosine receptors in rat brain by (?)[3H]N6-phenylisopropyladenosine

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of P1-(A2b subtype) and P2-purinoceptors to the control of vascular tone in the rat isolated mesenteric arterial bed.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive modulation of intracellular Ca2+ levels by adenosine A2b receptors, prostacyclin, and prostaglandin E1 via a cholera toxin-sensitive mechanism in human erythroleukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calculating the dissociation constant of an unlabeled compound from the concentration required to displace radiolabel binding by 50%

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

8-Substituted xanthines as antagonists at A1- and A2-adenosine receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine A2B receptors: a novel therapeutic target in asthma?

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adenosine A2B receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,3-Dialkyl-8-(p-sulfophenyl)xanthines: potent water-soluble antagonists for A1- and A2-adenosine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/12014951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/JM0104318

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6927247&resulttype=core&format=json

13 May 2020

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