(Q40732356)

English

Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cancer cells: enhanced intracellular stability of novel sFv-F(c) intrabodies

scientific article

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Characterization of anti-cyclin E single-chain Fv antibodies and intrabodies in breast cancer cells: enhanced intracellular stability of novel sFv-F(c) intrabodies (English)

1 reference

Europe PubMed Central

23 September 2017

author name string

Randall W Strube

1

1 reference

Europe PubMed Central

23 September 2017

Si-Yi Chen

2

1 reference

Europe PubMed Central

23 September 2017

publication date

1 May 2002

1 reference

Europe PubMed Central

23 September 2017

Journal of Immunological Methods

1 reference

Europe PubMed Central

23 September 2017

263

1 reference

Europe PubMed Central

23 September 2017

1-2

1 reference

Europe PubMed Central

23 September 2017

149-167

1 reference

Europe PubMed Central

23 September 2017

Apoptosis induced in mammalian cells by small peptides that functionally antagonize the Rb-regulated E2F transcription factor

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Intracellular immunization with cytosolic recombinant antibodies.

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Single-chain antigen-binding proteins

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Inhibition of HIV-1 infection by down-regulation of the CXCR4 co-receptor using an intracellular single chain variable fragment against CXCR4.

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Decreased levels of the cell-cycle inhibitor p27Kip1 protein: prognostic implications in primary breast cancer

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7 January 2021

Intracellular antibodies as a new class of therapeutic molecules for gene therapy

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Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists

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Ras and p53 intracellular targeting with recombinant single-chain Fv (scFv) fragments: a novel approach for cancer therapy?

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Targeted tumor killing via an intracellular antibody against erbB-2.

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Potent inhibition of human immunodeficiency virus type 1 replication by an intracellular anti-Rev single-chain antibody

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Molecular and virological effects of intracellular anti-Rev single-chain variable fragments on the expression of various human immunodeficiency virus-1 strains

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Cell cycle control of DNA replication by a homologue from human cells of the p34cdc2 protein kinase

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Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

1 reference

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7 January 2021

Cyclin E uses Cdc6 as a chromatin-associated receptor required for DNA replication

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Rapid and reliable cloning of antibody variable regions and generation of recombinant single chain antibody fragments

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

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Recombinant antibody constructs in cancer therapy

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Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli

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3 Protein engineering of single-chain Fv analogs and fusion proteins

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Sequence requirements for nuclear location of simian virus 40 large-T antigen

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Tetracycline-induced expression of an anti-c-Myb single-chain antibody and its inhibitory effect on proliferation of the human leukemia cell line K562.

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7 January 2021

Redundant cyclin overexpression and gene amplification in breast cancer cells

1 reference

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7 January 2021

Cyclin E controls S phase progression and its down-regulation during Drosophila embryogenesis is required for the arrest of cell proliferation.

1 reference

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7 January 2021

Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

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7 January 2021

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

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Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner

1 reference

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7 January 2021

Intracellular expression of antibody fragments directed against HIV reverse transcriptase prevents HIV infection in vitro

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Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

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Human anti-HIV-1 tat sFv intrabodies for gene therapy of advanced HIV-1-infection and AIDS.

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7 January 2021

A C-terminal signal prevents secretion of luminal ER proteins

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Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

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Deregulation of cyclin E and D1 in breast cancer is associated with inactivation of the retinoblastoma protein

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G1-S transition defects occur in most breast cancers and predict outcome

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Cyclin-dependent regulation of G1 in mammalian fibroblasts.

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Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

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Targeting vectors for intracellular immunisation.

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Phenotypic knock-out of the latent membrane protein 1 of Epstein-Barr virus by an intracellular single-chain antibody

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Expression of cell-cycle regulators p27Kip1 and cyclin E, alone and in combination, correlate with survival in young breast cancer patients

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Tumor-specific proteolytic processing of cyclin E generates hyperactive lower-molecular-weight forms

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Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

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DNA sequencing with chain-terminating inhibitors

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Phase II study of the cyclin-dependent kinase inhibitor flavopiridol administered to patients with advanced gastric carcinoma.

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Lack of cyclin E immunoreactivity in non-malignant breast and association with proliferation in breast cancer

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Deregulated cyclin E induces chromosome instability

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Functional deletion of the CCR5 receptor by intracellular immunization produces cells that are refractory to CCR5-dependent HIV-1 infection and cell fusion

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Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry

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Extended half-life and elevated steady-state level of a single-chain Fv intrabody are critical for specific intracellular retargeting of its antigen, caspase-7.

1 reference

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The adenovirus E1A-associated kinase consists of cyclin E-p33cdk2 and cyclin A-p33cdk2.

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10.1016/S0022-1759(02)00035-2

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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