(Q40749668)

English

Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines.

scientific article published on August 2000

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scholarly article

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9 November 2019

Altered expression of BRCA1, BRCA2, and a newly identified BRCA2 exon 12 deletion variant in malignant human ovarian, prostate, and breast cancer cell lines (English)

1 reference

Europe PubMed Central

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9 November 2019

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9 November 2019

author name string

C Rauh-Adelmann

1

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9 November 2019

N Sabeti

3

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9 November 2019

J P Long

4

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9 November 2019

S C Mok

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9 November 2019

S M Ho

6

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9 November 2019

publication date

1 August 2000

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9 November 2019

Molecular Carcinogenesis

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9 November 2019

28

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9 November 2019

236-246

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9 November 2019

4

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9 November 2019

describes a project that uses

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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Identification of the breast cancer susceptibility gene BRCA2

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Down-regulation of BRCA1 and BRCA2 in human ovarian cancer cells exposed to adriamycin and ultraviolet radiation.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Evidence for a transcriptional activation function of BRCA1 C-terminal region

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Human Rad51 protein promotes ATP-dependent homologous pairing and strand transfer reactions in vitro

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Transcriptional activation functions in BRCA2

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Changes in BRCA2 expression during progression of the cell cycle

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

BRCA1 regulates p53-dependent gene expression

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

In situ visualization of DNA double-strand break repair in human fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

The BRCA2 is a histone acetyltransferase

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Functional evidence for a breast cancer growth suppressor gene on chromosome 17.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

BRCA1 mutations in primary breast and ovarian carcinomas.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Low incidence of BRCA2 mutations in breast carcinoma and other cancers

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Clinical impact of detection of loss of heterozygosity of BRCA1 and BRCA2 markers in sporadic breast cancer

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Down-regulation of BRCA1 in human sporadic breast cancer; analysis of DNA methylation patterns of the putative promoter region

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Estrogen upregulation of BRCA1 expression with no effect on localization.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Inhibition of BRCA-1 expression by benzo[a]pyrene and its diol epoxide

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Preferential allelic expression can lead to reduced expression of BRCA1 in sporadic breast cancers.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Characterization of human ovarian surface epithelial cells immortalized by human papilloma viral oncogenes (HPV-E6E7 ORFs).

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Expression of human estrogen receptor-alpha and -beta, progesterone receptor, and androgen receptor mRNA in normal and malignant ovarian epithelial cells

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Overexpression of BRCA2 gene in sporadic breast tumours.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Immunohistochemical expression of BRCA2 protein and allelic loss at the BRCA2 locus in prostate cancer. CRC/BPG UK Familial Prostate Cancer Study Collaborators.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

BRCA1 expression is not directly responsive to estrogen.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

The developmental pattern of Brca1 expression implies a role in differentiation of the breast and other tissues

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Developmental expression of Brca2 colocalizes with Brca1 and is associated with proliferation and differentiation in multiple tissues.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Growth retardation and tumour inhibition by BRCA1.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Breast cancer susceptibility genes. BRCA1 and BRCA2.

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Differential subcellular localization, expression and biological toxicity of BRCA1 and the splice variant BRCA1-delta11b

1 reference

https://api.crossref.org/works/10.1002%2F1098-2744%28200008%2928%3A4%3C236%3A%3AAID-MC6%3E3.0.CO%3B2-H

21 January 2018

Identifiers

10.1002/1098-2744(200008)28:4<236::AID-MC6>3.0.CO;2-H

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10972993%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10972993%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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