(Q40753323)

English

Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy

scientific article published on April 1999

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy (English)

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

author name string

Vajkoczy P

1

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Menger MD

2

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Vollmar B

3

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Schilling L

4

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Schmiedek P

5

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Hirth KP

6

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Ullrich A

7

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Fong TA

8

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

publication date

1 April 1999

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

1

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

31-41

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Flk-1 as a target for tumor growth inhibition.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Tyrosine kinase inhibition: an approach to drug development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

A pial window model for the intracranial study of human glioma microvascular function

1 reference

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24 September 2017

Vascularity and perfusion of human gliomas xenografted in the athymic nude mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Angiogenesis in cancer, vascular, rheumatoid and other disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

The vasculature of experimental brain tumours. Part 1. A sequential light and electron microscope study of angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Microcirculatory Basis of Fluid Exchange

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Angiogenic factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Signal transduction by receptors with tyrosine kinase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Isolation of a human placenta cDNA coding for a protein related to the vascular permeability factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

What Is the Evidence That Tumors Are Angiogenesis Dependent?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Molecular and biological properties of the vascular endothelial growth factor family of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

24 September 2017

Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

25 September 2017

Assessment of brain tumor cell motility in vivo and in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

25 September 2017

Invading C6 glioma cells maintaining tumorigenicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

25 September 2017

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Quantitative angiogenesis assays: progress and problems

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Prevention of pancreatic islet xenograft rejection by dietary vitamin E.

1 reference

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17 June 2018

Grafting of fast blue labeled glial cells into neonatal rat brain: differential survival and migration among cell types

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Histogenesis and ultrastructure of pancreatic islet graft microvasculature. Evidence for graft revascularization by endothelial cells of host origin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Tumor angiogenesis: a quantitative method for histologic grading.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

A quantitative assessment of microvessel ultrastructure in C6 astrocytoma spheroids transplanted to brain and to muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

The microvascular architecture of human malignant glioma. A scanning electron microscopic study of a vascular cast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

17 June 2018

Angiogenesis, microvascular architecture, microhemodynamics, and interstitial fluid pressure during early growth of human adenocarcinoma LS174T in SCID mice

1 reference

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17 June 2018

Inhibitors of nitric oxide synthase selectively reduce flow in tumor-associated neovasculature

1 reference

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17 June 2018

Nitric oxide synthase is expressed in experimental malignant glioma and influences tumour blood flow.

1 reference

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3 July 2018

Neovascularization induced growth of implanted C6 glioma multicellular spheroids: magnetic resonance microimaging.

1 reference

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27 July 2018

Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

27 July 2018

Characterization of angiogenesis and microcirculation of high-grade glioma: an intravital multifluorescence microscopic approach in the athymic nude mouse.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

19 August 2018

Up-regulation of vascular endothelial growth factor and its cognate receptors in a rat glioma model of tumor angiogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1716058

19 August 2018

Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative immunohistological analysis of the microvasculature in untreated human glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis and vascularization of murine pancreatic islet isografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor angiogenesis and interstitial hypertension

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

On-line volume flow rate and velocity profile measurement for blood in microvessels

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vascular permeability factor, an endothelial cell mitogen related to PDGF

1 reference

https://pubmed.ncbi.nlm.nih.gov/10935468

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.NEO.7900006

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

23 September 2017

ResearchGate publication ID

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