(Q40753521)

23 September 2017

A co-culture-based model of human blood-brain barrier: application to active transport of indinavir and in vivo-in vitro correlation (English)

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23 September 2017

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Isabelle Megard

1

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23 September 2017

Alexia Garrigues

2

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23 September 2017

Stéphane Orlowski

3

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23 September 2017

Sylvie Jorajuria

4

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23 September 2017

Pascal Clayette

5

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23 September 2017

Eric Ezan

6

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23 September 2017

Aloïse Mabondzo

7

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23 September 2017

1 February 2002

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23 September 2017

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23 September 2017

927

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23 September 2017

2

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23 September 2017

153-167

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Characterization of an in vitro blood-brain barrier model system for studying drug transport and metabolism.

23 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Comparative interleukin (IL-2)/interferon IFN-gamma and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated nef-truncated or pathogenic SICmac251 virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Polarity of the blood-brain barrier: Distribution of enzymes between the luminal and antiluminal membranes of brain capillary endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

HTLV-III, AIDS, and the brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Cytokine mRNA expression in mononuclear cells from different tissues during acute SIVmac251 infection of macaques

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

An easier, reproducible, and mass-production method to study the blood-brain barrier in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Amino acid substitutions in the sixth transmembrane domain of P-glycoprotein alter multidrug resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Inhibition of P-glycoprotein: rapid assessment of its implication in blood-brain barrier integrity and drug transport to the brain by an in vitro model of the blood-brain barrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Astrocytes increase the functional expression of P-glycoprotein in an in vitro model of the blood-brain barrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Absence of cooperativity for MgATP and verapamil effects on the ATPase activity of P-glycoprotein containing membrane vesicles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Competitive and non-competitive inhibition of the multidrug-resistance-associated P-glycoprotein ATPase--further experimental evidence for a multisite model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Correlation between n-octanol/water partition coefficient and liquid chromatographic retention for caffeine and its metabolites, and some structure-pharmacokinetic considerations

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

P-Glycoprotein on astrocyte foot processes of unfixed isolated human brain capillaries.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

In vitro blood-brain barrier permeability of nevirapine compared to other HIV antiretroviral agents.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Expression of multidrug resistance-associated protein (MRP) in brain microvessel endothelial cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Properties of an immortalised vascular endothelial/glioma cell co-culture model of the blood-brain barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Bispecific antibody targeting of human immunodeficiency virus type 1 (HIV-1) glycoprotein 41 to human macrophages through the Fc IgG receptor I mediates neutralizing effects in HIV-1 infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Indinavir-based treatment of HIV-1 infected patients: efficacy in the central nervous system.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long-term culture.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

ATP-dependent transport of amphiphilic cations across the hepatocyte canalicular membrane mediated by mdr1 P-glycoprotein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Central nervous system as a sanctuary for HIV-1 infection despite treatment with zidovudine, lamivudine and indinavir

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Preliminary characterization of glial-secreted factors responsible for the induction of high electrical resistances across endothelial monolayers in a blood-brain barrier model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Effects of cardiovascular drugs on ATPase activity of P-glycoprotein in plasma membranes and in purified reconstituted form

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Early penetration of the blood-brain-barrier by HIV.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

A cell culture model of the blood-brain barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Protease inhibitors may reverse AIDS dementia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Human immunodeficiency virus protease inhibitors serve as substrates for multidrug transporter proteins MDR1 and MRP1 but retain antiviral efficacy in cell lines expressing these transporters

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Indinavir in cerebrospinal fluid of HIV-1-infected patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

A new model of the blood--brain barrier: co-culture of neuronal, endothelial and glial cells under dynamic conditions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Establishment of the permanent microvascular endothelial cell line PBMEC/C1-2 from porcine brains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Assessment of active transport of HIV protease inhibitors in various cell lines and the in vitro blood--brain barrier.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Effect of the p-glycoprotein inhibitor, cyclosporin A, on the distribution of rhodamine-123 to the brain: an in vivo microdialysis study in freely moving rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

Interaction of anti-HIV protease inhibitors with the multidrug transporter P-glycoprotein (P-gp) in human cultured cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-8993%2801%2903337-6

10.1016/S0006-8993(01)03337-6

7 January 2021

Identifiers

DOI

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23 September 2017

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