(Q40758149)

23 September 2017

title

Apoptosis stimulated by the 91-kDa caspase cleavage MEKK1 fragment requires translocation to soluble cellular compartments (English)

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23 September 2017

7

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23 September 2017

Thomas K Schlesinger

1

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23 September 2017

Christelle Bonvin

2

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23 September 2017

Matthew B Jarpe

3

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23 September 2017

Gary R Fanger

4

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23 September 2017

Jean-Rene Cardinaux

5

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23 September 2017

Gary L Johnson

6

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23 September 2017

language of work or name

English

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publication date

8 January 2002

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

issue

12

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23 September 2017

page(s)

10283-10291

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Programmed cell death in animal development

23 September 2017

cites work

1 reference

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21 January 2018

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21 January 2018

Caspases: enemies within

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Caspase-dependent cleavage of signaling proteins during apoptosis. A turn-off mechanism for anti-apoptotic signals

21 January 2018

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Mammalian caspases: structure, activation, substrates, and functions during apoptosis

21 January 2018

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Stimulation of p300-mediated transcription by the kinase MEKK1.

21 January 2018

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Signal transduction pathways regulated by mitogen-activated/extracellular response kinase kinase kinase induce cell death

21 January 2018

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

21 January 2018

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The regulation of anoikis: MEKK-1 activation requires cleavage by caspases

21 January 2018

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MEK kinase 1, a substrate for DEVD-directed caspases, is involved in genotoxin-induced apoptosis

21 January 2018

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Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter

21 January 2018

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

21 January 2018

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Sortilin/neurotensin receptor-3: a new tool to investigate neurotensin signaling and cellular trafficking?

21 January 2018

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Potentiation of apoptosis by low dose stress stimuli in cells expressing activated MEK kinase 1.

21 January 2018

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Membrane-targeted green fluorescent protein reliably and uniquely marks cells through apoptotic death.

21 January 2018

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Derived protein sequence, oligosaccharides, and membrane insertion of the 120-kDa lysosomal membrane glycoprotein (lgp120): identification of a highly conserved family of lysosomal membrane glycoproteins

21 January 2018

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Cas mediates transcriptional activation of the serum response element by Src.

21 January 2018

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Antiapoptotic signaling generated by caspase-induced cleavage of RasGAP.

21 January 2018

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MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

21 January 2018

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Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain

21 January 2018

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A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106885200

14-3-3 proteins interact with specific MEK kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Direct interaction between Ras and the kinase domain of mitogen-activated protein kinase kinase kinase (MEKK1).

21 January 2018

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All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

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A polybasic domain or palmitoylation is required in addition to the CAAX motif to localize p21ras to the plasma membrane

21 January 2018

1 reference

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Caspases: killer proteases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106885200

Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

21 January 2018

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Anti-apoptotic versus pro-apoptotic signal transduction: checkpoints and stop signs along the road to death.

21 January 2018

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The Jnk1 and Jnk2 protein kinases are required for regional specific apoptosis during early brain development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

A role for Jun-N-terminal kinase in anoikis; suppression by bcl-2 and crmA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Lack of correlation between activation of Jun-NH2-terminal kinase and induction of apoptosis after detachment of epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Stress-signalling kinase Sek1 protects thymocytes from apoptosis mediated by CD95 and CD3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106885200

NF-kappaB to the rescue: RELs, apoptosis and cellular transformation

21 January 2018

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Control of apoptosis by Rel/NF-kappaB transcription factors

21 January 2018

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M106885200

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

21 January 2018

Bcl-2 family proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Differential involvement of MEK kinase 1 (MEKK1) in the induction of apoptosis in response to microtubule-targeted drugs versus DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Cisplatin induces the proapoptotic conformation of Bak in a deltaMEKK1-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Caspase structure, proteolytic substrates, and function during apoptotic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Role of NF-κB in p53-mediated programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106885200

21 January 2018

Identifiers

DOI

10.1074/JBC.M106885200

1 reference

23 September 2017

1 reference