(Q40758291)

English

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase.

scientific article published on December 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781820%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Phosphorylation and structure-based functional studies reveal a positive and a negative role for the activation loop of the c-Abl tyrosine kinase (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781820%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

phosphorylation

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inferred from title

1

1 reference

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5 December 2019

Giulio Superti-Furga

7

1 reference

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5 December 2019

2

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5 December 2019

4

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5 December 2019

author name string

Kretzschmar J

3

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5 December 2019

Neubauer G

5

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5 December 2019

Schindler T

6

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5 December 2019

language of work or name

0 references

publication date

1 December 2001

1 reference

Europe PubMed Central

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5 December 2019

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781820%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

20

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5 December 2019

56

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5 December 2019

8075-8084

1 reference

Europe PubMed Central

PubMed publication ID

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5 December 2019

https://scigraph.springernature.com/pub.10.1038/sj.onc.1205017

0 references

Coordinate activation of c-Src by SH3- and SH2-binding sites on a novel p130Cas-related protein, Sin.

1 reference

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7 January 2021

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An activating mutation in the ATP binding site of the ABL kinase domain.

1 reference

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7 January 2021

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A nuclear tyrosine phosphorylation circuit: c-Jun as an activator and substrate of c-Abl and JNK.

1 reference

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7 January 2021

based on heuristic

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An intramolecular SH3-domain interaction regulates c-Abl activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Abl has high intrinsic tyrosine kinase activity that is stimulated by mutation of the Src homology 3 domain and by autophosphorylation at two distinct regulatory tyrosines

1 reference

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7 January 2021

based on heuristic

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Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation

1 reference

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7 January 2021

based on heuristic

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Characterization of a novel member of the DOK family that binds and modulates Abl signaling

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

p140/c-Abl that binds DNA is preferentially phosphorylated at tyrosine residues

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Mutational analysis of the Src SH3 domain: the same residues of the ligand binding surface are important for intra- and intermolecular interactions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Crosstalk between the catalytic and regulatory domains allows bidirectional regulation of Src.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

The protein kinase family: conserved features and deduced phylogeny of the catalytic domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Src autoinhibition: let us count the ways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Structural analysis of receptor tyrosine kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

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Crystal structure of the tyrosine kinase domain of the human insulin receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Active and inactive protein kinases: structural basis for regulation

1 reference

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7 January 2021

based on heuristic

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Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

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Structure of a peptide inhibitor bound to the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

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Essential roles for the Abl and Arg tyrosine kinases in neurulation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Detection of c-abl tyrosine kinase activity in vitro permits direct comparison of normal and altered abl gene products

1 reference

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7 January 2021

based on heuristic

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An alteration of the human c-abl protein in K562 leukemia cells unmasks associated tyrosine kinase activity.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

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MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Vertebrate non-receptor protein-tyrosine kinase families

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

SH1 domain autophosphorylation of P210 BCR/ABL is required for transformation but not growth factor independence

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

c-Abl is activated by growth factors and Src family kinases and has a role in the cellular response to PDGF

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Signal transduction by wild-type and leukemogenic Abl proteins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

The nuclear tyrosine kinase c-Abl negatively regulates cell growth

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

The catalytic subunit of cAMP-dependent protein kinase: prototype for an extended network of communication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the Abl tyrosine kinase in vivo by Src homology 3 domains from the Src homology 2/Src homology 3 adaptor Nck.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205017

7 January 2021

based on heuristic

inferred from DOI database lookup

Cycling, stressed-out and nervous: cellular functions of c-Abl

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

WHAT IF: a molecular modeling and drug design program

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphorylation of the Abelson murine leukemia virus transforming protein

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Structural basis for activation of human lymphocyte kinase Lck upon tyrosine phosphorylation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Signaling pathways activated by oncogenic forms of Abl tyrosine kinase

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.ONC.1205017

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781820%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11781820%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

ResearchGate publication ID

0 references

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