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CD28 as a molecular amplifier extending TCR ligation and signaling capabilities.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
title
CD28 as a molecular amplifier extending TCR ligation and signaling capabilities
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author
Frédérique Michel
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
Giorgio Mangino
series ordinal
3
1 reference
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Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
author name string
G Attal-Bonnefoy
series ordinal
2
1 reference
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Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
S Mise-Omata
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
O Acuto
series ordinal
5
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
language of work or name
English
0 references
publication date
1 December 2001
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
number of pages
11
1 reference
based on heuristic
inferred from page(s)
published in
Immunity
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
volume
15
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
issue
6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
page(s)
935-945
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
cites work
CD28 is associated with and induces the immediate tyrosine phosphorylation and activation of the Tec family kinase ITK/EMT in the human Jurkat leukemic T-cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD2 sets quantitative thresholds in T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
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inferred from DOI database lookup
Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Rho-family GTP exchange factor Vav is a critical transducer of T cell receptor signals to the calcium, ERK, and NF-kappaB pathways
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structure and ligand interactions of CD2: implications for T-cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokines, virokines and the evolution of immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cyclosporin A specifically inhibits function of nuclear proteins involved in T cell activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Absence of B7-dependent responses in CD28-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Coordinate regulation of T cell activation by CD2 and CD28
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Characteristics of antigen-independent and antigen-dependent interaction of dendritic cells with CD4+ T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Major histocompatibility complex independent clonal T cell anergy by direct interaction of Staphylococcus aureus enterotoxin B with the T cell antigen receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of lipid rafts in T cell antigen receptor (TCR) signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Duration of TCR stimulation determines costimulatory requirement of T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28/B7 system of T cell costimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tec kinases: modulators of lymphocyte signaling and development
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The structural basis of T cell activation by superantigens.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell antigen CD28 mediates adhesion with B cells by interacting with activation antigen B7/BB-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fyn and ZAP-70 are required for Vav phosphorylation in T cells stimulated by antigen-presenting cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 utilizes Vav-1 to enhance TCR-proximal signaling and NF-AT activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of p21ras in CD28 signal transduction: triggering of CD28 with antibodies, but not the ligand B7-1, activates p21ras
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding of phosphatidylinositol-3-OH kinase to CD28 is required for T-cell signalling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct intracytoplasmic regions of the T-cell adhesion molecule CD28 participate in phosphatidylinositol 3-kinase association
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD3 stimulation causes phosphorylation of phospholipase C-gamma 1 on serine and tyrosine residues in a human T-cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p56Lck and p59Fyn regulate CD28 binding to phosphatidylinositol 3-kinase, growth factor receptor-bound protein GRB-2, and T cell-specific protein-tyrosine kinase ITK: implications for T-cell costimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Upstream-downstream: CD28 cosignaling pathways and T cell function
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Resting lymphocyte kinase (Rlk/Txk) targets lymphoid adaptor SLP-76 in the cooperative activation of interleukin-2 transcription in T-cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential T cell costimulatory requirements in CD28-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 ligation induces tyrosine phosphorylation of Pyk2 but not Fak in Jurkat T cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 affects the earliest signaling events generated by TCR engagement
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD80 (B7-1) binds both CD28 and CTLA-4 with a low affinity and very fast kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell antigen-receptor signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T cell activation determined by T cell receptor number and tunable thresholds.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T lymphocyte costimulation mediated by reorganization of membrane microdomains
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28: a signalling perspective.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a phospholipase C-gamma1 (PLC-gamma1) SH3 domain-binding site in SLP-76 required for T-cell receptor-mediated activation of PLC-gamma1 and NFAT
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of Tec protein-tyrosine kinase in T cell signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 co-stimulates TCR/CD3-induced phosphoinositide turnover in human T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1074-7613%2801%2900244-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1074-7613(01)00244-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
Fatcat ID
release_25qfnm2nybe75iyuydlzorbkea
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/25qfnm2nybe75iyuydlzorbkea
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PubMed publication ID
11754815
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11754815
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11754815%20AND%20SRC:MED&resulttype=core&format=json
retrieved
5 December 2019
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