(Q40763797)

23 September 2017

title

The binding site for channel blockers that rescue misprocessed human long QT syndrome type 2 ether-a-gogo-related gene (HERG) mutations (English)

1 reference

23 September 2017

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Eckhard Ficker

1

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23 September 2017

Carlos A Obejero-Paz

series ordinal

2

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23 September 2017

Shuxia Zhao

series ordinal

3

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23 September 2017

Arthur M Brown

series ordinal

4

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23 September 2017

language of work or name

English

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publication date

10 December 2001

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Journal of Biological Chemistry

23 September 2017

published in

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23 September 2017

volume

277

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23 September 2017

issue

7

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23 September 2017

page(s)

4989-4998

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

23 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Novel gain-of-function mechanism in K(+) channel-related long-QT syndrome: altered gating and selectivity in the HERG1 N629D mutant.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

HERG channel dysfunction in human long QT syndrome. Intracellular transport and functional defects

21 January 2018

1 reference

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Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Defective aquaporin-2 trafficking in nephrogenic diabetes insipidus and correction by chemical chaperones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Processing of mutant cystic fibrosis transmembrane conductance regulator is temperature-sensitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Glycerol reverses the misfolding phenotype of the most common cystic fibrosis mutation.

21 January 2018

1 reference

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Chemical chaperones correct the mutant phenotype of the delta F508 cystic fibrosis transmembrane conductance regulator protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Pharmacological chaperones rescue cell-surface expression and function of misfolded V2 vasopressin receptor mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Correction of defective protein trafficking of a mutant HERG potassium channel in human long QT syndrome. Pharmacological and temperature effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.

21 January 2018

1 reference

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A structural basis for drug-induced long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

The selectivity of different external binding sites for quaternary ammonium ions in cloned potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

MiRP1 forms IKr potassium channels with HERG and is associated with cardiac arrhythmia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

A mechanism for the proarrhythmic effects of cisapride (Propulsid): high affinity blockade of the human cardiac potassium channel HERG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Modulation of HERG potassium channels by extracellular magnesium and quinidine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Interaction of Tetraethylammonium Ion Derivatives with the Potassium Channels of Giant Axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Inactivation of potassium current in squid axon by a variety of quaternary ammonium ions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

The inward rectification mechanism of the HERG cardiac potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Probing the interaction between inactivation gating and Dd-sotalol block of HERG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

The internal quaternary ammonium receptor site of Shaker potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Mutations affecting internal TEA blockade identify the probable pore-forming region of a K+ channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Recombination of protein domains facilitated by co-translational folding in eukaryotes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

Correction of Defective Protein Kinesis of Human P-glycoprotein Mutants by Substrates and Modulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M107345200

21 January 2018

Identifiers

DOI

10.1074/JBC.M107345200

1 reference

23 September 2017

1 reference