(Q40768240)

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Two clusters of residues at the docking groove of mitogen-activated protein kinases differentially mediate their functional interaction with the tyrosine phosphatases PTP-SL and STEP.

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3 December 2019

Two clusters of residues at the docking groove of mitogen-activated protein kinases differentially mediate their functional interaction with the tyrosine phosphatases PTP-SL and STEP (English)

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11711538%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Carmen Blanco-Aparicio

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3 December 2019

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3 December 2019

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Céline Tárrega

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3 December 2019

Juan José Muñoz

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3 December 2019

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15 November 2001

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3 December 2019

Journal of Biological Chemistry

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3 December 2019

277

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3 December 2019

2629-2636

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3 December 2019

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3 December 2019

New insights into the control of MAP kinase pathways

1 reference

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21 January 2018

Organization and regulation of mitogen-activated protein kinase signaling pathways

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21 January 2018

Mitogen-activated protein kinases: specific messages from ubiquitous messengers

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Signaling specificity: the RTK/RAS/MAP kinase pathway in metazoans

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21 January 2018

The Ras signaling pathway in Drosophila

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21 January 2018

p38 MAP kinases: beyond the stress response

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21 January 2018

A role for autophosphorylation revealed by activated alleles of FUS3, the yeast MAP kinase homolog

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21 January 2018

A gain-of-function mutation in Drosophila MAP kinase activates multiple receptor tyrosine kinase signaling pathways.

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21 January 2018

The osmoregulatory pathway represses mating pathway activity in Saccharomyces cerevisiae: isolation of a FUS3 mutant that is insensitive to the repression mechanism

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21 January 2018

The sevenmaker gain-of-function mutation in p42 MAP kinase leads to enhanced signalling and reduced sensitivity to dual specificity phosphatase action

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21 January 2018

The mitogen-activated protein kinase phosphatases PAC1, MKP-1, and MKP-2 have unique substrate specificities and reduced activity in vivo toward the ERK2 sevenmaker mutation

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21 January 2018

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

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21 January 2018

Interaction of MAP kinase with MAP kinase kinase: its possible role in the control of nucleocytoplasmic transport of MAP kinase

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21 January 2018

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

1 reference

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21 January 2018

Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation

1 reference

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21 January 2018

Growth factor-induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins

1 reference

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21 January 2018

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

1 reference

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21 January 2018

Extracellular signals and scores of phosphatases: all roads lead to MAP kinase

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21 January 2018

A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase

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21 January 2018

Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry

1 reference

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21 January 2018

Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1

1 reference

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21 January 2018

Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase

1 reference

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21 January 2018

Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm

1 reference

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21 January 2018

A conserved docking motif in MAP kinases common to substrates, activators and regulators

1 reference

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21 January 2018

Identification of a docking groove on ERK and p38 MAP kinases that regulates the specificity of docking interactions

1 reference

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21 January 2018

Hydrophobic as well as charged residues in both MEK1 and ERK2 are important for their proper docking

1 reference

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21 January 2018

Biochemical and biological functions of the N-terminal, noncatalytic domain of extracellular signal-regulated kinase 2.

1 reference

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21 January 2018

PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108874200

21 January 2018

Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP)

1 reference

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21 January 2018

A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission

1 reference

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21 January 2018

Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

1 reference

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21 January 2018

How MAP kinases are regulated

1 reference

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21 January 2018

Sequence of pp42/MAP kinase, a serine/threonine kinase regulated by tyrosine phosphorylation

1 reference

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21 January 2018

FUS3 encodes a cdc2+/CDC28-related kinase required for the transition from mitosis into conjugation.

1 reference

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21 January 2018

Primary structure, expression, and signal-dependent tyrosine phosphorylation of a Drosophila homolog of extracellular signal-regulated kinase

1 reference

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21 January 2018

Atomic structure of the MAP kinase ERK2 at 2.3 A resolution

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21 January 2018

A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

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21 January 2018

Biochemical characterization of rolledSem, an activated form of Drosophila mitogen-activated protein kinase.

1 reference

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21 January 2018

An osmosensing signal transduction pathway in mammalian cells.

1 reference

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21 January 2018

Isolation of hyperactive mutants of the MAPK p38/Hog1 that are independent of MAPK kinase activation

1 reference

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21 January 2018

Discordance between the binding affinity of mitogen-activated protein kinase subfamily members for MAP kinase phosphatase-2 and their ability to activate the phosphatase catalytically

1 reference

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21 January 2018

Crystal structure of PTP-SL/PTPBR7 catalytic domain: implications for MAP kinase regulation

1 reference

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21 January 2018

ERK1b, a 46-kDa ERK isoform that is differentially regulated by MEK

1 reference

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21 January 2018

Altered regulation of ERK1b by MEK1 and PTP-SL and modified Elk1 phosphorylation by ERK1b are caused by abrogation of the regulatory C-terminal sequence of ERKs

1 reference

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21 January 2018

Activation mechanism of the MAP kinase ERK2 by dual phosphorylation

1 reference

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21 January 2018

The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP

1 reference

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21 January 2018

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain

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21 January 2018

Transient compartmental expression of a family of protein tyrosine phosphatases in the developing striatum

1 reference

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21 January 2018

The mouse Ptprr gene encodes two protein tyrosine phosphatases, PTP-SL and PTPBR7, that display distinct patterns of expression during neural development.

1 reference

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21 January 2018

Cloning of PCPTP1-Ce encoding protein tyrosine phosphatase from the rat cerebellum and its restricted expression in Purkinje cells

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21 January 2018

Protein tyrosine phosphatase (PC12, Br7,S1) family: expression characterization in the adult human and mouse

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21 January 2018

Molecular cloning and chromosomal mapping of a human protein-tyrosine phosphatase LC-PTP

1 reference

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21 January 2018

Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase)

1 reference

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21 January 2018

PTP-ER, a novel tyrosine phosphatase, functions downstream of Ras1 to downregulate MAP kinase during Drosophila eye development

1 reference

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The influence of the MAPK pathway on T cell lineage commitment

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21 January 2018

Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1.

1 reference

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21 January 2018

Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases

1 reference

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21 January 2018

Differential regulation of FUS3 MAP kinase by tyrosine-specific phosphatases PTP2/PTP3 and dual-specificity phosphatase MSG5 in Saccharomyces cerevisiae

1 reference

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21 January 2018

A specific protein-protein interaction accounts for the in vivo substrate selectivity of Ptp3 towards the Fus3 MAP kinase

1 reference

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21 January 2018

Catalytic activation of mitogen-activated protein (MAP) kinase phosphatase-1 by binding to p38 MAP kinase: critical role of the p38 C-terminal domain in its negative regulation

1 reference

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21 January 2018

The riddle of MAP kinase signaling specificity

1 reference

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21 January 2018

Isolation and characterization of mutants of human mitogen-activated protein kinase (ERK2)

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Catalytic Activation of the Phosphatase MKP-3 by ERK2 Mitogen-Activated Protein Kinase

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21 January 2018

Identifiers

10.1074/JBC.M108874200

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11711538%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11711538%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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