(Q40768808)

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Repression of glucagon gene transcription by peroxisome proliferator-activated receptor gamma through inhibition of Pax6 transcriptional activity

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Europe PubMed Central

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23 September 2017

Repression of glucagon gene transcription by peroxisome proliferator-activated receptor gamma through inhibition of Pax6 transcriptional activity (English)

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Europe PubMed Central

PubMed publication ID

23 September 2017

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Sven Schinner

1

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Europe PubMed Central

PubMed publication ID

23 September 2017

Claudia Dellas

2

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Europe PubMed Central

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23 September 2017

Margit Schroder

3

1 reference

Europe PubMed Central

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23 September 2017

Cynthia A Heinlein

4

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Europe PubMed Central

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23 September 2017

Chawnshang Chang

5

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Europe PubMed Central

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23 September 2017

Janina Fischer

6

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23 September 2017

Willhart Knepel

7

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23 September 2017

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13 November 2001

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Europe PubMed Central

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23 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

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23 September 2017

277

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Europe PubMed Central

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23 September 2017

3

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Europe PubMed Central

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23 September 2017

1941-1948

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Europe PubMed Central

PubMed publication ID

23 September 2017

Peroxisome proliferator-activated receptors: nuclear control of metabolism

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Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma

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p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers

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21 January 2018

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Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene

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PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines

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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator-activated receptor gamma

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Activation of human T lymphocytes is inhibited by peroxisome proliferator-activated receptor gamma (PPARgamma) agonists. PPARgamma co-association with transcription factor NFAT.

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Suppression of rat thromboxane synthase gene transcription by peroxisome proliferator-activated receptor gamma in macrophages via an interaction with NRF2.

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21 January 2018

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21 January 2018

Medical significance of peroxisome proliferator-activated receptors.

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The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

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Thiazolidinediones: an update.

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Treatment of insulin resistance with peroxisome proliferator-activated receptor gamma agonists

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The hormone resistin links obesity to diabetes

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21 January 2018

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

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21 January 2018

Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes

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21 January 2018

Insulinlike activity of new antidiabetic agent CP 68722 in 3T3-L1 adipocytes

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21 January 2018

Actions of novel antidiabetic agent englitazone in hyperglycemic hyperinsulinemic ob/ob mice

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Possibility of distinct insulin-signaling pathways beyond phosphatidylinositol 3-kinase-mediating glucose transport and lipogenesis

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21 January 2018

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones

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21 January 2018

Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat

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21 January 2018

Role of peroxisome proliferator-activated receptor alpha in disease of pancreatic beta cells

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21 January 2018

Glucagon and the A cell: physiology and pathophysiology (first two parts).

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21 January 2018

Glucagon and its family revisited

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21 January 2018

Blood glucose lowering and glucagonostatic effects of glucagon-like peptide I in insulin-deprived diabetic dogs.

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21 January 2018

Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients.

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21 January 2018

Glucagon-like peptides

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21 January 2018

Characterization of a novel protein kinase C response element in the glucagon gene

1 reference

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21 January 2018

Insulin responsiveness of the glucagon gene conferred by interactions between proximal promoter and more distal enhancer-like elements involving the paired-domain transcription factor Pax6.

1 reference

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21 January 2018

Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma

1 reference

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21 January 2018

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

1 reference

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21 January 2018

Isolation of glucagon-secreting cell lines by cloning insulinoma cells

1 reference

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21 January 2018

Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins

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Involvement of the Ca(2+)-dependent phosphatase calcineurin in gene transcription that is stimulated by cAMP through cAMP response elements

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Transcriptional activation of the rat glucagon gene by the cyclic AMP-responsive element in pancreatic islet cells

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Characterization of a novel calcium response element in the glucagon gene

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The Pancreatic Islet-Specific Glucagon G3 Transcription Factors Recognize Control Elements in the Rat Somatostatin and Insulin-I Genes

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Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

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Pax6 and Cdx2/3 form a functional complex on the rat glucagon gene promoter G1-element

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POU domain transcription factor brain 4 confers pancreatic alpha-cell-specific expression of the proglucagon gene through interaction with a novel proximal promoter G1 element

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Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3.

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N-(2-Benzoylphenyl)-L-tyrosine PPARgamma agonists. 1. Discovery of a novel series of potent antihyperglycemic and antihyperlipidemic agents

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Pax genes and their roles in cell differentiation and development

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Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells

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Heterodimeric Pbx-Prep1 homeodomain protein binding to the glucagon gene restricting transcription in a cell type-dependent manner.

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Peroxisome proliferator-activated receptor γ activators inhibit interleukin-12 production in murine dendritic cells

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Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

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Repression of TNF-alpha-induced E-selectin expression by PPAR activators: involvement of transcriptional repressor LRF-1/ATF3

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Expression of peroxisome proliferator-activated receptor γ (PPARγ) in normal human pancreatic islet cells

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15 July 2023

Identifiers

10.1074/JBC.M109718200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

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