(Q40771131)

23 September 2017

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title

Interleukin-6 in autoimmune disease. Role of IL-6 in physiology and pathology of the immune defense (English)

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23 September 2017

L Graeve

1

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PubMed ID

8219666

23 September 2017

M Baumann

series ordinal

2

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PubMed ID

8219666

23 September 2017

P C Heinrich

series ordinal

3

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23 September 2017

1 August 1993

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Journal of Molecular Medicine

23 September 2017

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23 September 2017

71

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23 September 2017

664-671

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23 September 2017

8

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https://scigraph.springernature.com/pub.10.1007/bf00184499

23 September 2017

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Interleukins 1, 4 and 6 induce the colony formation of human bone marrow B lineage cells

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Aggregated immunoglobulin and Fc fragment of IgG induce IL-6 release from human monocytes

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Independent induction of interleukin 6 and prostaglandin E2 by interleukin 1 in human articular chondrocytes

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A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family

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12 December 2020

IL-6 and IL-1 synergize to stimulate IL-2 production and proliferation of peripheral T cells.

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Constitutive production of interleukin-6 and immunologic features in cardiac myxomas

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Endogenous interleukin 6 plays an obligatory role in interleukin 4-dependent human IgE synthesis

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Production and modulation of interleukin 6 synthesis by synoviocytes derived from patients with arthritic disease

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12 December 2020

Correlation of synovial fluid interleukin 6 (IL-6) activities with IgG concentrations in patients with inflammatory joint disease and osteoarthritis

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12 December 2020

Interleukins and IgA synthesis. Human and murine interleukin 6 induce high rate IgA secretion in IgA-committed B cells

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Human recombinant IL-6/B cell stimulatory factor 2 augments murine antigen-specific antibody responses in vitro and in vivo.

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Role of interleukin 6 in fever in rats

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12 December 2020

Interleukin-6 production by tumor necrosis factor and lipopolysaccharide-stimulated rat renal cells

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12 December 2020

Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by human fibroblasts

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12 December 2020

Recombinant interleukin-6 inhibits the growth of rat mesangial cells in culture

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12 December 2020

A cell culture model for T lymphocyte clonal anergy

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Essential role for interferon-gamma and interleukin-6 in autoimmune insulin-dependent diabetes in NOD/Wehi mice

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Human polysaccharide-specific B cells are responsive to pokeweed mitogen and IL-6

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Receptors for B cell stimulatory factor 2. Quantitation, specificity, distribution, and regulation of their expression

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Regulation of BSF-2/IL-6 production by human mononuclear cells. Macrophage-dependent synthesis of BSF-2/IL-6 by T cells

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12 December 2020

Serial estimation of interleukin 6 as a measure of systemic disease in rheumatoid arthritis

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12 December 2020

Interleukin-1-induced interleukin-6 is required for the inhibition of proteoglycan synthesis by interleukin-1 in human articular cartilage

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12 December 2020

IgG1 plasmacytosis in interleukin 6 transgenic mice

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12 December 2020

Interleukin-6 in synovial fluid from patients with arthritis

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12 December 2020

In situ hybridization of IL-6 in rheumatoid arthritis

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12 December 2020

Interleukin-6 and its receptor: a paradigm for cytokines

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12 December 2020

Giant lymph node hyperplasia (Castleman's disease) with spontaneous production of high levels of B-cell differentiation factor activity

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12 December 2020

Evidence for IL-6 production by and effects on the pancreatic beta-cell

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12 December 2020

Interferon-beta 2/interleukin 6 is a co-stimulant for human T lymphocytes

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12 December 2020

Pathogenic significance of interleukin-6 (IL-6/BSF-2) in Castleman's disease

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12 December 2020

Interleukin-6 in synovial fluid and serum of patients with rheumatoid arthritis and other inflammatory arthritides

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12 December 2020

Interleukin-6 is constitutively produced by human CTL clones and is required to maintain their cytolytic function

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12 December 2020

The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells

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12 December 2020

Minimal growth requirements of mature T lymphocytes: interleukin (IL)-1 and IL-6 increase growth rate but not plating efficiency of CD4 cells stimulated with anti-CD3 and IL-2

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12 December 2020

Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor

1 reference

12 December 2020

Interleukin-6 induces the synthesis of tissue inhibitor of metalloproteinases-1/erythroid potentiating activity (TIMP-1/EPA)

1 reference

12 December 2020

Analysis of human IL-6 mutants expressed in Escherichia coli. Biologic activities are not affected by deletion of amino acids 1-28.

1 reference

12 December 2020

Interleukin-1 beta induces synthesis and secretion of interleukin-6 in human chondrocytes

1 reference

12 December 2020

Autostimulatory effects of IL-6 on excessive B cell differentiation in patients with systemic lupus erythematosus: analysis of IL-6 production and IL-6R expression

1 reference

12 December 2020

Acute-phase response factor, a nuclear factor binding to acute-phase response elements, is rapidly activated by interleukin-6 at the posttranslational level

1 reference

12 December 2020

Interleukin-6: an overview

1 reference

12 December 2020

Activation of neutrophils by recombinant interleukin 6

1 reference

12 December 2020

Recombinant interleukin (IL) 2-induced human B cell differentiation is mediated by autocrine IL6

1 reference

12 December 2020

Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells

1 reference

12 December 2020

Cytokine levels in the cerebrospinal fluid and serum of patients with multiple sclerosis

1 reference

12 December 2020

T cell derived IL-6 is differentially required for antigen-specific antibody secretion by primary and secondary B cells.

1 reference

12 December 2020

IL-6 is a potent cofactor of IL-1 in IgM synthesis and of IL-5 in IgA synthesis

1 reference

12 December 2020

IL-2 dependence of the promotion of human B cell differentiation by IL-6 (BSF-2).

1 reference

12 December 2020

Antigen presentation by keratinocytes induces tolerance in human T cells

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12 December 2020

The prognostic significance of urinary interleukin 6 in IgA nephropathy

1 reference

12 December 2020

IL-4-supported induction of cytolytic T lymphocytes requires IL-2 and IL-6.

1 reference

12 December 2020

Castleman's disease in POEMS syndrome with elevated interleukin-6

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12 December 2020

Biological and clinical aspects of interleukin 6.

1 reference

12 December 2020

Synergistic interactions of IL-1 and IL-6 in T cell activation. Mitogen but not antigen receptor-induced proliferation of a cloned T helper cell line is enhanced by exogenous IL-6.

1 reference

12 December 2020

Elevated levels of endogenous IL-6 in systemic lupus erythematosus. A putative role in pathogenesis.

1 reference

12 December 2020

Induction of human B cell differentiation by Fc region activators. II. Stimulation of IL-6 production

1 reference

12 December 2020

Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes

1 reference

12 December 2020

Interleukin-6 and the acute phase response

1 reference

12 December 2020

Constitutive production of inflammatory and mitogenic cytokines by rheumatoid synovial fibroblasts

1 reference

12 December 2020

IL-6/BSF-2 functions as a killer helper factor in the in vitro induction of cytotoxic T cells

1 reference

12 December 2020

IL-6 production by human articular chondrocytes. Modulation of its synthesis by cytokines, growth factors, and hormones in vitro

1 reference

12 December 2020

Cross-linking Fc receptors on monocytes triggers IL-6 production. Role in anti-CD3-induced T cell activation

1 reference

12 December 2020

IFN-beta 2/IL-6 augments the activity of human natural killer cells

1 reference

12 December 2020

B-cell-stimulatory factor 2 (beta 2 interferon) functions as a second signal for interleukin 2 production by mature murine T cells

1 reference

12 December 2020

The three carboxy-terminal amino acids of human interleukin-6 are essential for its biological activity

1 reference

12 December 2020

Tissue destruction by neutrophils

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12 December 2020

Correlation between rheumatoid factor and IL-6 activity in synovial fluids from patients with rheumatoid arthritis

1 reference

12 December 2020

Interleukin-6 is pyrogenic but not somnogenic

1 reference

12 December 2020

Mitogenic effect of platelet-derived growth factor in human glomerular mesangial cells: modulation and/or suppression by inflammatory cytokines

1 reference

12 December 2020

IL-2 and IL-6 synergize to augment the pore-forming protein gene expression and cytotoxic potential of human peripheral blood T cells

1 reference

12 December 2020

Molecular cloning, characterization and functional expression of the rat liver interleukin 6 receptor

1 reference

12 December 2020

Cytokine gene expression in the islets of the diabetic Biobreeding/Worcester rat

1 reference

12 December 2020

Dysregulated interleukin 6 expression produces a syndrome resembling Castleman's disease in mice.

1 reference

12 December 2020

Recombinant human interleukin 6 (rhIL-6) promotes the terminal differentiation of in vivo-activated human B cells into antibody-secreting cells

1 reference

12 December 2020

Age-associated increase in interleukin 6 in MRL/lpr mice

1 reference

12 December 2020

Structure-function analysis of human IL-6. Epitope mapping of neutralizing monoclonal antibodies with amino- and carboxyl-terminal deletion mutants

1 reference

12 December 2020

Interleukin 6 production in the central nervous system during experimental autoimmune encephalomyelitis

1 reference

12 December 2020

Human T cell activation with phytohemagglutinin. The function of IL-6 as an accessory signal

1 reference

12 December 2020

Cooperation between an anti-T cell (anti-CD28) monoclonal antibody and monocyte-produced IL-6 in the induction of T cell responsiveness to IL-2

1 reference

12 December 2020

Autoimmune diseases: the failure of self tolerance

1 reference

12 December 2020

Excessive production of interleukin 6/B cell stimulatory factor-2 in rheumatoid arthritis

1 reference

12 December 2020

Synergistic activation of human T cells by interleukin 1 and interleukin 6

1 reference

12 December 2020

Monoclonal IgGs from an autoimmune MRL/Mp-lpr/lpr mouse induce an interleukin-3-dependent myeloid cell line to produce tumor necrosis factor alpha and interleukin-6.

1 reference

12 December 2020

Synovium as a source of interleukin 6 in vitro. Contribution to local and systemic manifestations of arthritis

1 reference

12 December 2020

The role of human interleukin-6 in B-cell isotype regulation and differentiation

1 reference

12 December 2020

Enhanced production of interleukin-6 in mice with type II collagen-induced arthritis

1 reference

12 December 2020

Interleukin 1 and tumor necrosis factor-alpha synergistically increase the production of interleukin 6 in human synovial fibroblast

1 reference

12 December 2020

Glucocorticosteroid-dependent synergy between interleukin 1 and interleukin 6 for human B lymphocyte differentiation

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF00184499

1 reference

23 September 2017

1 reference

PubMed ID

8219666