(Q40781201)

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Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Structural and functional characterization of human CXCR4 as a chemokine receptor and HIV-1 co-receptor by mutagenesis and molecular modeling studies (English)

1 reference

Europe PubMed Central

23 September 2017

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author name string

Zhou N

1

1 reference

Europe PubMed Central

23 September 2017

Luo Z

2

1 reference

Europe PubMed Central

23 September 2017

Luo J

3

1 reference

Europe PubMed Central

23 September 2017

Liu D

4

1 reference

Europe PubMed Central

23 September 2017

Hall JW

5

1 reference

Europe PubMed Central

23 September 2017

Pomerantz RJ

6

1 reference

Europe PubMed Central

23 September 2017

Huang Z

7

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

10 September 2001

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Europe PubMed Central

23 September 2017

Journal of Biological Chemistry

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Europe PubMed Central

23 September 2017

276

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Europe PubMed Central

23 September 2017

46

1 reference

Europe PubMed Central

23 September 2017

42826-42833

1 reference

Europe PubMed Central

23 September 2017

Human chemokines: an update

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-line-adapted HIV-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Molecular mimicry of human cytokine and cytokine response pathway genes by KSHV.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Angiogenic and HIV-inhibitory functions of KSHV-encoded chemokines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

The molecular biology of leukocyte chemoattractant receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

CD4-independent infection by HIV-2 is mediated by fusin/CXCR4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Role of the amino-terminal extracellular domain of CXCR-4 in human immunodeficiency virus type 1 entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

CXCR4 sequences involved in coreceptor determination of human immunodeficiency virus type-1 tropism. Unmasking of activity with M-tropic Env glycoproteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Substitutions in a homologous region of extracellular loop 2 of CXCR4 and CCR5 alter coreceptor activities for HIV-1 membrane fusion and virus entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Entry of R5X4 and X4 human immunodeficiency virus type 1 strains is mediated by negatively charged and tyrosine residues in the amino-terminal domain and the second extracellular loop of CXCR4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Molecular modeling and site-directed mutagenesis of CCR5 reveal residues critical for chemokine binding and signal transduction.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Chemokine receptor trafficking and viral replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Structure of bacteriorhodopsin at 1.55 A resolution

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Solution structure and basis for functional activity of stromal cell-derived factor-1; dissociation of CXCR4 activation from binding and inhibition of HIV-1.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Comparison of the structure of vMIP-II with eotaxin-1, RANTES, and MCP-3 suggests a unique mechanism for CCR3 activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

The solution structure of the anti-HIV chemokine vMIP-II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Dissociation of the signalling and antiviral properties of SDF-1-derived small peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Antigen recognition by helper T cells elicits a sequence of distinct changes of their shape and intracellular calcium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

HIV coreceptor downregulation as antiviral principle: SDF-1alpha-dependent internalization of the chemokine receptor CXCR4 contributes to inhibition of HIV replication

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Visualization of G protein-coupled receptor trafficking with the aid of the green fluorescent protein. Endocytosis and recycling of cholecystokinin receptor type A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

N-terminal peptides of stromal cell-derived factor-1 with CXC chemokine receptor 4 agonist and antagonist activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

The role of positively charged residues in CXCR4 recognition probed with synthetic peptides

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Structure-function study and anti-HIV activity of synthetic peptide analogues derived from viral chemokine vMIP-II.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Structure/function of human herpesvirus-8 MIP-II (1-71) and the antagonist N-terminal segment (1-10)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Two-site binding of C5a by its receptor: an alternative binding paradigm for G protein-coupled receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A small region of the beta-adrenergic receptor is selectively involved in its rapid regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Effects of second intracellular loop mutations on signal transduction and internalization of the gonadotropin-releasing hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A small-molecule inhibitor directed against the chemokine receptor CXCR4 prevents its use as an HIV-1 coreceptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Inhibition of T-tropic HIV strains by selective antagonization of the chemokine receptor CXCR4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Expression and functional characterization of mutant human CXCR4 in insect cells: role of cysteinyl and negatively charged residues in ligand binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Molecular modeling of interleukin-8 receptor beta and analysis of the receptor-ligand interaction

1 reference

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21 January 2018

Attachment of C-terminus of SDF-1 enhances the biological activity of its N-terminal peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106582200

21 January 2018

Identifiers

10.1074/JBC.M106582200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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