(Q40785589)

23 September 2017

Disrupted bile acid homeostasis reveals an unexpected interaction among nuclear hormone receptors, transporters, and cytochrome P450. (English)

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23 September 2017

E G Schuetz

1

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23 September 2017

S Strom

2

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23 September 2017

K Yasuda

3

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23 September 2017

V Lecureur

4

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23 September 2017

M Assem

5

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23 September 2017

C Brimer

6

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23 September 2017

J Lamba

7

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23 September 2017

R B Kim

8

1 reference

23 September 2017

V Ramachandran

9

1 reference

23 September 2017

B J Komoroski

10

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23 September 2017

R Venkataramanan

11

1 reference

23 September 2017

H Cai

12

1 reference

23 September 2017

C J Sinal

13

1 reference

23 September 2017

F J Gonzalez

14

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23 September 2017

J D Schuetz

15

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23 September 2017

language of work or name

English

0 references

publication date

16 August 2001

1 reference

Journal of Biological Chemistry

23 September 2017

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23 September 2017

276

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23 September 2017

39411-39418

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23 September 2017

42

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Identification of a nuclear receptor for bile acids

23 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Identification of a locus for progressive familial intrahepatic cholestasis PFIC2 on chromosome 2q24

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Immunochemical evidence for multiple steroid-inducible hepatic cytochromes P-450 in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Regulation of gene expression in adult rat hepatocytes cultured on a basement membrane matrix

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Fallen arches, or how the vertebrate got its head

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Sp1 and egr-1 have opposing effects on the regulation of the rat Pgp2/mdr1b gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Nuclear receptor regulation of cholesterol and bile acid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Regulation of multidrug resistance 2 P-glycoprotein expression by bile salts in rats and in primary cultures of rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Cholestatic potential of troglitazone as a possible factor contributing to troglitazone-induced hepatotoxicity: in vivo and in vitro interaction at the canalicular bile salt export pump (Bsep) in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Lith1, a major gene affecting cholesterol gallstone formation among inbred strains of mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

MRP4: A previously unidentified factor in resistance to nucleoside-based antiviral drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Gallstone dissolution with ursodeoxycholic acid in patients with chronic active hepatitis and two years follow-up. A pilot study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The continuing importance of bile acids in liver and intestinal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

Bile acid structure and selective modulation of murine hepatic cytochrome P450-linked enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106340200

21 January 2018

Identifiers

DOI

10.1074/JBC.M106340200

1 reference

23 September 2017

1 reference