(Q40785864)

English

Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation

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scholarly article

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Europe PubMed Central

PubMed publication ID

23 September 2017

Probing conformational changes in the I-like domain and the cysteine-rich repeat of human beta 3 integrins following disulfide bond disruption by cysteine mutations: identification of cysteine 598 involved in alphaIIbbeta3 activation (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Chen P

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Melchior C

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Brons NH

3

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Schlegel N

4

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Caen J

5

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Kieffer N

6

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Europe PubMed Central

PubMed publication ID

23 September 2017

language of work or name

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publication date

15 August 2001

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Europe PubMed Central

PubMed publication ID

23 September 2017

number of pages

8

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Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

23 September 2017

276

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

42

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

38628-38635

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Integrins: emerging paradigms of signal transduction

1 reference

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

1 reference

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Integrin transmembrane signaling and cytoskeletal control

1 reference

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Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3).

1 reference

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Human neutrophil elastase proteolytically activates the platelet integrin alphaIIbbeta3 through cleavage of the carboxyl terminus of the alphaIIb subunit heavy chain. Involvement in the potentiation of platelet aggregation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

An isolated, surface-expressed I domain of the integrin alphaLbeta2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Locking in alternate conformations of the integrin alphaLbeta2 I domain with disulfide bonds reveals functional relationships among integrin domains

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

The platelet integrin alpha IIbbeta 3 has an endogenous thiol isomerase activity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Assignment of disulphide bonds in human platelet GPIIIa. A disulphide pattern for the beta-subunits of the integrin family

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

A novel activating anti-beta1 integrin monoclonal antibody binds to the cysteine-rich repeats in the beta1 chain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Topography of ligand-induced binding sites, including a novel cation-sensitive epitope (AP5) at the amino terminus, of the human integrin beta 3 subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

A structure prediction for the ligand-binding region of the integrin beta subunit: evidence for the presence of a von Willebrand factor A domain.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Molecular requirements for assembly and function of a minimized human integrin alphaIIbbeta3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

A variant of Glanzmann's thrombasthenia with abnormal glycoprotein IIb-IIIa complexes in the platelet membrane

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Divalent cation regulation of the surface orientation of platelet membrane glycoprotein IIb. Correlation with fibrinogen binding function and definition of a novel variant of Glanzmann's thrombasthenia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

A beta 3 integrin mutation abolishes ligand binding and alters divalent cation-dependent conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Platelet integrin GPIIb/IIIa: structure-function correlations. An update and lessons from other integrins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Protein disulfide isomerase mediates integrin-dependent adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Regulation of endothelial cell morphogenesis by integrins, mechanical forces, and matrix guidance pathways

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Affinity modulation in platelet alpha 2 beta 1 following ligand binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Protein disulphide isomerase mediates platelet aggregation and secretion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Distinct involvement of beta3 integrin cytoplasmic domain tyrosine residues 747 and 759 in integrin-mediated cytoskeletal assembly and phosphotyrosine signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Monoclonal Antibody 9EG7 Defines a Novel β1 Integrin Epitope Induced by Soluble Ligand and Manganese, but Inhibited by Calcium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

The top of the inserted-like domain of the integrin lymphocyte function-associated antigen-1 beta subunit contacts the alpha subunit beta -propeller domain near beta-sheet 3

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Homozygous Cys542-->Arg substitution in GPIIIa in a Swiss patient with type I Glanzmann's thrombasthenia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

A second case of variant of Glanzmann's thrombasthenia due to substitution of platelet GPIIIa (integrin beta 3) Arg214 by Trp

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M105737200

21 January 2018

Identifiers

10.1074/JBC.M105737200

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

ResearchGate publication ID

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