(Q40795310)

23 September 2017

title

Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain (English)

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23 September 2017

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4

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23 September 2017

Vaux EC

1

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23 September 2017

Metzen E

series ordinal

2

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23 September 2017

Yeates KM

series ordinal

3

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23 September 2017

language of work or name

English

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publication date

1 July 2001

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23 September 2017

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23 September 2017

volume

98

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23 September 2017

issue

2

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23 September 2017

page(s)

296-302

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The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

23 September 2017

cites work

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24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1038/20459

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

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24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1126/SCIENCE.2814477

Role of hydrogen peroxide in hypoxia-induced erythropoietin production

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Titrating the effects of mitochondrial complex I impairment in the cell physiology

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Inducible operation of the erythropoietin 3' enhancer in multiple cell lines: evidence for a widespread oxygen-sensing mechanism

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Hypoxia-inducible factor 1 levels vary exponentially over a physiologically relevant range of O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Different cellular backgrounds confer a marked advantage to either mutant or wild-type mitochondrial genomes.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Unresponsiveness of erythropoietin-producing cells to cyanide

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

The selection of Chinese hamster cells deficient in oxidative energy metabolism

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

The role of mitochondria in the regulation of hypoxia-inducible factor 1 expression during hypoxia

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

An essential role for p300/CBP in the cellular response to hypoxia

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12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

General involvement of hypoxia-inducible factor 1 in transcriptional response to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Conditionally lethal mutations in Chinese hamster cells. Characterization of a cell line with a possible defect in the krebs cycle

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Characterization of an oxygen/redox-dependent degradation domain of hypoxia-inducible factor alpha (HIF-alpha) proteins

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Respiration-deficient Chinese hamster cell mutants: Biochemical characterization

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Mitochondria and apoptosis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Chinese hamster cell mutant with defective mitochondrial protein synthesis

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1alpha during hypoxia: a mechanism of O2 sensing

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Hydroperoxide metabolism in mammalian organs

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Mammalian cells with defective mitochondrial functions: a Chinese hamster mutant cell line lacking succinate dehydrogenase activity

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Oxygen sensing and molecular adaptation to hypoxia

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1182/BLOOD.V98.2.296

Identifiers

DOI

10.1182/BLOOD.V98.2.296

1 reference

23 September 2017

1 reference