(Q40800354)

23 September 2017

title

Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms (English)

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23 September 2017

L Recio

1

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23 September 2017

A M Steen

2

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23 September 2017

L J Pluta

3

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23 September 2017

K G Meyer

4

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23 September 2017

C J Saranko

5

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23 September 2017

publication date

1 June 2001

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Chemico-biological Interactions

23 September 2017

published in

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23 September 2017

volume

135-136

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23 September 2017

page(s)

325-341

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The industrial production and use of 1,3-butadiene

23 September 2017

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Toxicology and epidemiology of 1,3-butadiene

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Comparison of the disposition of butadiene epoxides in Sprague-Dawley rats and B6C3F1 mice following a single and repeated exposures to 1,3-butadiene via inhalation

7 January 2021

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Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts

7 January 2021

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7 January 2021

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In vitro and in vivo mutagenicity of the butadiene metabolites butadiene diolepoxide, butadiene monoepoxide and diepoxybutane.

7 January 2021

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Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene

7 January 2021

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The in vivo mutagenicity and mutational spectrum at the lacI transgene recovered from the spleens of B6C3F1 lacI transgenic mice following a 4-week inhalation exposure to 1,3-butadiene

7 January 2021

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Comparison of the mutagenic potency of 1,3-butadiene at the hprt locus of T-lymphocytes following inhalation exposure of female B6C3F1 mice and F344 rats

7 January 2021

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Comparison of induction of hprt mutations by 1,3-butadiene and/or its metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane in lymphocytes from spleen of adult male mice and rats in vivo

7 January 2021

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New approaches to understanding p53 gene tumor mutation spectra

7 January 2021

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Characterization of hprt mutations following 1,2-epoxy-3-butene exposure of human TK6 cells

7 January 2021

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Analysis of hprt mutations occurring in human TK6 lymphoblastoid cells following exposure to 1,2,3,4-diepoxybutane

7 January 2021

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Molecular analysis of lacI mutants from transgenic fibroblasts exposed to 1,2-epoxybutene

7 January 2021

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The butadiene metabolite, 1,2:3,4-diepoxybutane, induces micronuclei but is only weakly mutagenic at lacI in the Big Blue Rat2 lacI transgenic cell line

7 January 2021

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Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene

7 January 2021

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Molecular analysis of lacI mutants from bone marrow of B6C3F1 transgenic mice following inhalation exposure to 1,3-butadiene.

7 January 2021

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Spontaneous and X-ray-induced deletion mutations in a LacZ plasmid-based transgenic mouse model

7 January 2021

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Allelotyping of butadiene-induced lung and mammary adenocarcinomas of B6C3F1 mice: frequent losses of heterozygosity in regions homologous to human tumor-suppressor genes

7 January 2021

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Hydroquinone, a benzene metabolite, increases the level of aneusomy of chromosomes 7 and 8 in human CD34-positive blood progenitor cells

7 January 2021

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Butadiene diolepoxide- and diepoxybutane-derived DNA adducts at N7-guanine: a high occurrence of diolepoxide-derived adducts in mouse lung after 1,3-butadiene exposure

7 January 2021

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Human DNA adducts of 1,3-butadiene, an important environmental carcinogen

7 January 2021

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Mutagenic potential of guanine N2 adducts of butadiene mono- and diolepoxide

7 January 2021

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Mutagenic potential of adenine N(6) adducts of monoepoxide and diolepoxide derivatives of butadiene

7 January 2021

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Butadiene-induced intrastrand DNA cross-links: a possible role in deletion mutagenesis

7 January 2021

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Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2',3'-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas

7 January 2021

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Mutations of ras protooncogenes and p53 tumor suppressor gene in cardiac hemangiosarcomas from B6C3F1 mice exposed to 1,3-butadiene for 2 years

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0009-2797%2801%2900220-4

10.1016/S0009-2797(01)00220-4

7 January 2021

Identifiers

DOI

1 reference

23 September 2017

1 reference