(Q40806753)

23 September 2017

title

Antitumor efficacy of SarCNU in a human glioma xenograft model expressing both MGMT and extraneuronal monoamine transporter (English)

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23 September 2017

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Chen ZP

1

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23 September 2017

Pan J

2

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23 September 2017

Huang Q

3

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23 September 2017

Sun ZF

4

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23 September 2017

Zhou LY

5

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23 September 2017

Wang AD

6

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23 September 2017

publication date

1 January 2001

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Journal of Neuro-Oncology

23 September 2017

published in

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23 September 2017

volume

51

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23 September 2017

issue

1

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23 September 2017

page(s)

19-24

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Evidence for nucleotide excision repair as a modifying factor of O6-methylguanine-DNA methyltransferase-mediated innate chloroethylnitrosourea resistance in human tumor cell lines

23 September 2017

cites work

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12 December 2020

1,3-Bis(2-Chloroethyl)-1-Nitrosourea (Bcnu) And Other Nitrosoureas In Cancer Treatment: A Review

1 reference

12 December 2020

Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study

1 reference

12 December 2020

Retrospective study of the correlation between the DNA repair protein alkyltransferase and survival of brain tumor patients treated with carmustine

1 reference

12 December 2020

O6-Alkylguanine-DNA alkyltransferase activity correlates with the therapeutic response of human rhabdomyosarcoma xenografts to 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea

1 reference

12 December 2020

Transport of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in the human glioma cell line SK-MG-1 is mediated by an epinephrine-sensitive carrier system

1 reference

12 December 2020

Excision repair cross-complementing rodent repair deficiency gene 2 expression and chloroethylnitrosourea resistance in human glioma cell lines

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12 December 2020

Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents

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12 December 2020

The extraneuronal transporter for monoamine transmitters exists in cells derived from human central nervous system glia.

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12 December 2020

Utilization of the HTSCA and CFU-C assay to identify two new 2-chloroethylnitrosourea congeners of amino acid amides with increased in vitro activity against human glioma compared with BCNU.

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12 December 2020

Mammalian O6-alkylguanine-DNA alkyltransferase: regulation and importance in response to alkylating carcinogenic and therapeutic agents

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12 December 2020

Drug resistance in brain tumors

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12 December 2020

Quantitation of ERCC-2 gene expression in human tumor cell lines by reverse transcription-polymerase chain reaction in comparison to northern blot analysis

1 reference

12 December 2020

(2-Chloroethyl)nitrosourea congeners of amino acid amides

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12 December 2020

Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents

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12 December 2020

Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter

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12 December 2020

Characterization of the catecholamine extraneuronal uptake2 carrier in human glioma cell lines SK-MG-1 and SKI-1 in relation to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) selective cytotoxicity

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12 December 2020

Altered cytotoxicity of (2-chloroethyl)-3-sarcosinamide-1-nitrosourea in human glioma cell lines SK-MG-1 and SKI-1 correlates with differential transport kinetics.

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12 December 2020

Extraneuronal monoamine transporter expression and DNA repair vis-à-vis 2-chloroethyl-3-sarcosinamide-1-nitrosourea cytotoxicity in human tumor cell lines.

1 reference

12 December 2020

Quantification of O6-methylguanine-DNA methyltransferase mRNA in human brain tumors

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12 December 2020

Determination of subcutaneous tumor size in athymic (nude) mice

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12 December 2020

Expression of the extraneuronal monoamine transporter (uptake2) in human glioma cells

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12 December 2020

SarCNU (2-chloroethyl-3-sarcosinamide-1-nitrosourea): a novel analogue of chloroethylnitrosourea that is transported by the catecholamine uptake2 carrier, which mediates increased cytotoxicity

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12 December 2020

Enhanced antitumor activity of sarCNU in comparison to BCNU in an extraneuronal monoamine transporter positive human glioma xenograft model

1 reference

12 December 2020

2-Chloroethyl-3-sarcosinamide-1-nitrosourea, a novel chloroethylnitrosourea analogue with enhanced antitumor activity against human glioma xenografts

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12 December 2020

Relationship between O6-methylguanine-DNA methyltransferase levels and clinical response induced by chloroethylnitrosourea therapy in glioma patients

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12 December 2020

Mechanisms of resistance to (2-chloroethyl)-3-sarcosinamide-1-nitrosourea (SarCNU) in sensitive and resistant human glioma cells.

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12 December 2020

Identifiers

DOI

10.1023/A:1006480818373

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Dimensions Publication ID

23 September 2017

1023199173

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