(Q40809420)

English

Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains

scientific article published on April 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Introducing endogenous antigens into the major histocompatibility complex (MHC) class II presentation pathway. Both Ii mediated inhibition and enhancement of endogenous peptide/MHC class II presentation require the same Ii domains (English)

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

author name string

Frauwirth K

1

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

Shastri N

2

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

publication date

1 April 2001

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

102

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

405-415

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

A role for the transmembrane domain in the trimerization of the MHC class II-associated invariant chain.

1 reference

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14 September 2018

Cloning genes encoding MHC class II-restricted antigens: mutated CDC27 as a tumor antigen

1 reference

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14 September 2018

Evidence that binding site occupancy is necessary and sufficient for effective major histocompatibility complex (MHC) class II transport through the secretory pathway redefines the primary function of class II-associated invariant chain peptides (CL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Predominant HLA-class II bound self-peptides of a hematopoietic progenitor cell line are derived from intracellular proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Antigen presentation and T cell development in H2-M-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Medullary thymic epithelial cells induce tolerance to intracellular proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Endogenous generation and presentation of the ovalbumin peptide/Kb complex to T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Relationship between invariant chain expression and major histocompatibility complex class II transport into early and late endocytic compartments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Characterization of endogenous peptides bound to purified HLA-DR molecules and their absence from invariant chain-associated alpha beta dimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The segment of invariant chain that is critical for association with major histocompatibility complex class II molecules contains the sequence of a peptide eluted from class II polypeptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Structural analysis of proteolytic products of MHC class II-invariant chain complexes generated in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The invariant chain is required for intracellular transport and function of major histocompatibility complex class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Major histocompatibility complex class II-restricted presentation of secreted and endoplasmic reticulum resident antigens requires the invariant chains and is sensitive to lysosomotropic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

LacZ inducible, antigen/MHC-specific T cell hybrids

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Defective major histocompatibility complex class II assembly, transport, peptide acquisition, and CD4+ T cell selection in mice lacking invariant chain expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The CLIP region of invariant chain plays a critical role in regulating major histocompatibility complex class II folding, transport, and peptide occupancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The invariant chain inhibits presentation of endogenous antigens by a human fibroblast cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Deletion of a C-terminal sequence of the class II-associated invariant chain abrogates invariant chains oligomer formation and class II antigen presentation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain cleavage and peptide loading in major histocompatibility complex class II vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Epitope-specific enhancement of antigen presentation by invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Mice lacking the MHC class II-associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

DM enhances peptide binding to class II MHC by release of invariant chain-derived peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Expression of endogenous peptide-major histocompatibility complex class II complexes derived from invariant chain-antigen fusion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Mapping functional regions in the lumenal domain of the class II-associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Diversity of endogenous epitopes bound to MHC class II molecules limited by invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

The expressed T cell repertoire is hierarchical: the precise focus of lysozyme-specific T cell clones is dependent upon the structure of the immunogen.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Efficient cell surface expression of class II MHC molecules in the absence of associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

A role of Ia-associated invariant chains in antigen processing and presentation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Ia molecule-associated selectivity in T cell recognition of a 23-amino-acid peptide of lysozyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Intracellular transport of class II MHC molecules directed by invariant chain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain distinguishes between the exogenous and endogenous antigen presentation pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain association with HLA-DR molecules inhibits immunogenic peptide binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

MHC class II-associated invariant chain contains a sorting signal for endosomal compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Antigen presentation of hen egg-white lysozyme but not of ribonuclease A is augmented by the major histocompatibility complex class II-associated invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Formation of a nine-subunit complex by HLA class II glycoproteins and the invariant chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain promotes egress of poorly expressed, haplotype-mismatched class II major histocompatibility complex A alpha A beta dimers from the endoplasmic reticulum/cis-Golgi compartment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain influences the immunological recognition of MHC class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Sequence analysis of peptides bound to MHC class II molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Correlation between invariant chain expression level and capability to present antigen to MHC class II-restricted T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Antigen presentation enhanced by the alternatively spliced invariant chain gene product p41.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Assembly and transport properties of invariant chain trimers and HLA-DR-invariant chain complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Characterization of peptides bound to the class I MHC molecule HLA-A2.1 by mass spectrometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Invariant chain peptides in most HLA-DR molecules of an antigen-processing mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

HLA-DR molecules from an antigen-processing mutant cell line are associated with invariant chain peptides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Peptides presented to the immune system by the murine class II major histocompatibility complex molecule I-Ad

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1783207

14 September 2018

Dendritic cells permit identification of genes encoding MHC class II-restricted epitopes of transplantation antigens

1 reference

https://pubmed.ncbi.nlm.nih.gov/11328374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Invariant chain prevents the HLA-DR-restricted presentation of a cytosolic peptide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11328374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunological significances of invariant chain from the aspect of its structural homology with the cystatin family

1 reference

https://pubmed.ncbi.nlm.nih.gov/11328374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Positive selection of T cells induced by viral delivery of neopeptides to the thymus

1 reference

https://pubmed.ncbi.nlm.nih.gov/11328374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ia invariant chain detected on lymphocyte surfaces by monoclonal antibody

1 reference

https://pubmed.ncbi.nlm.nih.gov/11328374

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2567.2001.01208.X

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

23 September 2017

ResearchGate publication ID

0 references

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