(Q40815132)

English

Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression

scientific article published on April 2001

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

Effects of genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21(waf/cip1), p27(kip1), and Cdc25C expression (English)

1 reference

Europe PubMed Central

24 September 2017

author name string

Frey RS

1

1 reference

Europe PubMed Central

24 September 2017

Li J

2

1 reference

Europe PubMed Central

24 September 2017

Singletary KW

3

1 reference

Europe PubMed Central

24 September 2017

language of work or name

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publication date

1 April 2001

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Europe PubMed Central

24 September 2017

number of pages

11

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Biochemical Pharmacology

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Europe PubMed Central

24 September 2017

61

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Europe PubMed Central

24 September 2017

8

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Europe PubMed Central

24 September 2017

979-989

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Europe PubMed Central

24 September 2017

Eating to beat breast cancer: potential role for soy supplements

1 reference

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Antioxidant and antipromotional effects of the soybean isoflavone genistein.

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Biochemical targets of the isoflavone genistein in tumor cell lines

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Molecular effects of genistein on estrogen receptor mediated pathways

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Dietary Estrogens Act through Estrogen Receptor-Mediated Processes and Show No Antiestrogenicity in Cultured Breast Cancer Cells

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Effects of tyrosine kinase inhibitors on the proliferation of human breast cancer cell lines and proteins important in the ras signaling pathway

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Genistein modulates neuroblastoma cell proliferation and differentiation through induction of apoptosis and regulation of tyrosine kinase activity and N-myc expression.

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Inhibition of ultraviolet B (UVB)-induced c-fos and c-jun expression in vivo by a tyrosine kinase inhibitor genistein.

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7 January 2021

Genistein inhibits proliferation similarly in estrogen receptor-positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2/M arrest, and apoptosis

1 reference

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7 January 2021

The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes

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Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin

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Growth inhibition with reversible cell cycle arrest of carcinoma cells by flavone L86-8275

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Dietary genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats

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7 January 2021

The role of metabolism in mammary epithelial cell growth inhibition by the isoflavones genistein and biochanin A.

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Mitosis in transition

1 reference

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Cyclin activation of p34cdc2.

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Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

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7 January 2021

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport

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Sodium butyrate induces G2 arrest in the human breast cancer cells MDA-MB-231 and renders them competent for DNA rereplication

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7 January 2021

Involvement of p21 in the PKC-induced regulation of the G2/M cell cycle transition

1 reference

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7 January 2021

Assessment of antineoplastic agents by MTT assay: partial underestimation of antiproliferative properties

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Altered transforming growth factor signaling in epithelial cells when ras activation is blocked

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7 January 2021

A novel inhibitor of cyclin-Cdk activity detected in transforming growth factor beta-arrested epithelial cells

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7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

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7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

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7 January 2021

Genistein and erbstatin inhibition of normal mammary epithelial cell proliferation is associated with EGF-receptor down-regulation.

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7 January 2021

Growth-inhibitory effects of the natural phyto-oestrogen genistein in MCF-7 human breast cancer cells

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7 January 2021

p53-independent apoptosis induced by genistein in lung cancer cells

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Induction of apoptosis in breast cancer cells MDA-MB-231 by genistein

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p53-independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone genistein in human prostate carcinoma cells.

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7 January 2021

Animal cell cycles and their control

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Blockade of TGFbeta3 up-regulation of p27Kip1 and p21Cip1 by expression of RasN17 in epithelial cells.

1 reference

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7 January 2021

Differential expression of cyclin D2 and cdc2 genes in proliferating and nonproliferating alveolar epithelial cells

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7 January 2021

Inhibition of proliferation and modulation of estradiol metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol.

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7 January 2021

Inhibition of aberrant proliferation and induction of apoptosis in HER-2/neu oncogene transformed human mammary epithelial cells by N-(4-hydroxyphenyl)retinamide

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Negative growth regulation of oncogene-transformed human breast epithelial cells by phytochemicals. Role of apoptosis

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Potent inhibition of CDC2 kinase activity by the flavonoid L86-8275.

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Xenograft model of progressive human proliferative breast disease

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7 January 2021

Identifiers

10.1016/S0006-2952(01)00572-X

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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