(Q40816848)

24 September 2017

title

Biochemical and biological characterization of a human Rac2 GTPase mutant associated with phagocytic immunodeficiency (English)

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24 September 2017

Gu Y

1

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24 September 2017

Jia B

2

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24 September 2017

Yang FC

3

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24 September 2017

D'Souza M

4

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24 September 2017

Harris CE

5

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24 September 2017

Derrow CW

6

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24 September 2017

Zheng Y

7

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24 September 2017

Williams DA

8

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24 September 2017

language of work or name

English

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publication date

22 February 2001

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

276

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24 September 2017

issue

19

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24 September 2017

page(s)

15929-15938

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Human neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutation

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Involvement of GTP-binding proteins in actin polymerization in human neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rho effectors and reorganization of actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rho GTPases and signaling networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rho GTPases and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

rac1 regulates a cytokine-stimulated, redox-dependent pathway necessary for NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Characterization of RAC3, a novel member of the Rho family

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M010445200

The biochemical basis of the NADPH oxidase of phagocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Regulation of phagocyte oxygen radical production by the GTP-binding protein Rac 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Deficiency of the hematopoietic cell-specific Rho family GTPase Rac2 is characterized by abnormalities in neutrophil function and host defense

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Guanine nucleotide binding properties of Rac2 mutant proteins and analysis of the responsiveness to guanine nucleotide dissociation stimulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rac1, a low-molecular-mass GTP-binding-protein with high intrinsic GTPase activity and distinct biochemical properties

21 January 2018

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Progress in the use of gene transfer methods to treat genetic blood diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

SmgGDS stabilizes nucleotide-bound and -free forms of the Rac1 GTP-binding protein and stimulates GTP/GDP exchange through a substituted enzyme mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Identification of Rho GTPase-dependent sites in the Dbl homology domain of oncogenic Dbl that are required for transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Role of kit-ligand in proliferation and suppression of apoptosis in mast cells: basis for radiosensitivity of white spotting and steel mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Two types of RAS mutants that dominantly interfere with activators of RAS.

21 January 2018

1 reference

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Colocalization of retrovirus and target cells on specific fibronectin fragments increases genetic transduction of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Rac and Cdc42 induce actin polymerization and G1 cell cycle progression independently of p65PAK and the JNK/SAPK MAP kinase cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Signaling from Ras to Rac and beyond: not just a matter of GEFs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

The GTPase superfamily: conserved structure and molecular mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Structure of the guanine-nucleotide-binding domain of the Ha-ras oncogene product p21 in the triphosphate conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010445200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010445200

1 reference

24 September 2017

1 reference