(Q40832484)

24 September 2017

title

Identification of a mutated DNA ligase IV gene in the X-ray-hypersensitive mutant SX10 of mouse FM3A cells (English)

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24 September 2017

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K Sado

1

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24 September 2017

D Ayusawa

2

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24 September 2017

A Enomoto

3

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24 September 2017

T Suganuma

4

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24 September 2017

M Oshimura

5

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24 September 2017

K Sato

6

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24 September 2017

H Koyama

7

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24 September 2017

language of work or name

English

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publication date

22 December 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

276

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24 September 2017

issue

13

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24 September 2017

page(s)

9742-9748

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describes a project that uses

24 September 2017

FM3A SX10

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cites work

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Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease

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Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines

21 January 2018

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DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK.

21 January 2018

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The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination

21 January 2018

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Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV

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Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells

21 January 2018

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Ku80: product of the XRCC5 gene and its role in DNA repair and V(D)J recombination

21 January 2018

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Ku70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombination

21 January 2018

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Ku, a DNA repair protein with multiple cellular functions?

21 January 2018

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DNA-PK: at the cross-roads of biochemistry and genetics

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The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigen

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DNA-dependent kinase (p350) as a candidate gene for the murine SCID defect

21 January 2018

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Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

21 January 2018

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Defective DNA-dependent protein kinase activity is linked to V(D)J recombination and DNA repair defects associated with the murine scid mutation.

21 January 2018

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Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint

21 January 2018

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Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

21 January 2018

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Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes

21 January 2018

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DNA double-strand break repair in two radiation-sensitive mouse mammary carcinoma cell lines

21 January 2018

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Characterization of two DNA double-stranded break repair-deficient cell lines that express inactive DNA-dependent protein kinase catalytic subunits

21 January 2018

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Transfer of Genetic Information by Purified Metaphase Chromosomes

21 January 2018

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Gene targeting for somatic cell manipulation: rapid analysis of reduced chromosome hybrids by Alu-PCR fingerprinting and chromosome painting

21 January 2018

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Characterization of the 3' untranslated region of mouse DNA topoisomerase IIalpha mRNA.

21 January 2018

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DNA topoisomerase II inhibitors enhance random integration of transfected vectors into human chromosomes

21 January 2018

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Functional complementation of the radiation-sensitive mutant M10 cell line by human chromosome 5.

21 January 2018

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DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

21 January 2018

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Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange

21 January 2018

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Localization to chromosome 7q36.1 of the human XRCC2 gene, determining sensitivity to DNA-damaging agents

21 January 2018

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Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene

21 January 2018

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A CHO mutant, UV40, that is sensitive to diverse mutagens and represents a new complementation group of mitomycin C sensitivity.

21 January 2018

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The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells

21 January 2018

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Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination

21 January 2018

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Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

21 January 2018

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The human gene for xeroderma pigmentosum complementation group G (XPG) maps to 13q33 by fluorescence in situ hybridization

21 January 2018

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Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010530200

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

21 January 2018

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DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains

21 January 2018

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Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient

21 January 2018

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A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

21 January 2018

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Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice

21 January 2018

1 reference

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Structure and function of mammalian DNA ligases

21 January 2018

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Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction

21 January 2018

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High-frequency illegitimate integration of transfected DNA at preintegrated target sites in a mammalian genome

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M010530200

1 reference

release_w74s5amw7jfwjo7anwlajfdcty

24 September 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w74s5amw7jfwjo7anwlajfdcty

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference