(Q40838005)

24 September 2017

title

Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT(2C) receptor (English)

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24 September 2017

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A Rosendorff

1

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24 September 2017

B J Ebersole

series ordinal

2

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24 September 2017

S C Sealfon

series ordinal

3

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24 September 2017

language of work or name

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1 December 2000

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24 September 2017

published in

Molecular Brain Research

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24 September 2017

volume

84

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24 September 2017

issue

1-2

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24 September 2017

page(s)

90-96

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Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin

24 September 2017

cites work

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Mapping the binding site pocket of the serotonin 5-Hydroxytryptamine2A receptor. Ser3.36(159) provides a second interaction site for the protonated amine of serotonin but not of lysergic acid diethylamide or bufotenin

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Functional Microdomains in G-protein-coupled Receptors

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The conserved seven-transmembrane sequence NP(X)2,3Y of the G-protein-coupled receptor superfamily regulates multiple properties of the beta 2-adrenergic receptor

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Single-cysteine substitution mutants at amino acid positions 306-321 in rhodopsin, the sequence between the cytoplasmic end of helix VII and the palmitoylation sites: sulfhydryl reactivity and transducin activation reveal a tertiary structure

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Activation mechanism of human oxytocin receptor: a combined study of experimental and computer-simulated mutagenesis

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7 January 2021

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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Mutations of Tyr326 in the beta 2-adrenoceptor disrupt multiple receptor functions.

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Agonists induce conformational changes in transmembrane domains III and VI of the beta2 adrenoceptor

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The cytoplasmic tail of the human somatostatin receptor type 5 is crucial for interaction with adenylyl cyclase and in mediating desensitization and internalization

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A Conserved NPLFY Sequence Contributes to Agonist Binding and Signal Transduction but Is Not an Internalization Signal for the Type 1 Angiotensin II Receptor

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Constitutive activation of the beta2 adrenergic receptor alters the orientation of its sixth membrane-spanning segment

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A proposed structure for transmembrane segment 7 of G protein-coupled receptors incorporating an asn-Pro/Asp-Pro motif

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7 January 2021

Molecular modeling of serotonin, ketanserin, ritanserin and their 5-HT2C receptor interactions

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Structural and functional requirements for agonist-induced internalization of the human platelet-activating factor receptor

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7 January 2021

A network of conserved intramolecular contacts defines the off-state of the transmembrane switch mechanism in a seven-transmembrane receptor

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7 January 2021

Identification of Putative Sites of Interaction between the Human Formyl Peptide Receptor and G Protein

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Rhodopsin-family receptors associate with small G proteins to activate phospholipase D.

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7 January 2021

Cloning of the human serotonin 5-HT2 and 5-HT1C receptor subtypes

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The activation process of the alpha1B-adrenergic receptor: potential role of protonation and hydrophobicity of a highly conserved aspartate

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7 January 2021

Projection structure of frog rhodopsin in two crystal forms

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7 January 2021

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7 January 2021

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

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7 January 2021

Angiotensin II receptor endocytosis involves two distinct regions of the cytoplasmic tail. A role for residues on the hydrophobic face of a putative amphipathic helix

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7 January 2021

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Identifiers

DOI

1 reference

24 September 2017

1 reference