(Q40844112)

24 September 2017

Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line (English)

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24 September 2017

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A L Gartel

1

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24 September 2017

E Goufman

series ordinal

2

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24 September 2017

F Najmabadi

series ordinal

3

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24 September 2017

A L Tyner

series ordinal

4

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24 September 2017

language of work or name

English

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publication date

1 October 2000

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24 September 2017

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24 September 2017

19

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24 September 2017

5182-5188

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24 September 2017

45

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1203900

24 September 2017

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cites work

Sp1 and Sp3 regulate expression of the neuronal nicotinic acetylcholine receptor beta4 subunit gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

The role of the transcription factor Sp1 in regulating the expression of the WAF1/CIP1 gene in U937 leukemic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Cooperation of Sp1 and p300 in the induction of the CDK inhibitor p21WAF1/CIP1 during NGF-mediated neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Growth/cell cycle regulation of Sp1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Radiation-induced cell cycle arrest compromised by p21 deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Mice lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Members of the Sp transcription factor family control transcription from the uteroglobin promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Repeated CT elements bound by zinc finger proteins control the absolute and relative activities of the two principal human c-myc promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco-2 cells. Status of the pRb1 and pRb2 tumor suppressor gene products.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Histone deacetylase 1 can repress transcription by binding to Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

p21 (WAF1/CIP1) expression is induced in newly nondividing cells in diverse epithelia and during differentiation of the Caco-2 intestinal cell line.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Correlation of terminal cell cycle arrest of skeletal muscle with induction of p21 by MyoD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Transcription factors Sp1 and Sp3 alter vascular endothelial growth factor receptor expression through a novel recognition sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Characterization of the human endothelial nitric-oxide synthase promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

c-Jun transactivates the promoter of the human p21(WAF1/Cip1) gene by acting as a superactivator of the ubiquitous transcription factor Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Inhibition of the 3-hydroxy-3-methylglutaryl-coenzyme A reductase pathway induces p53-independent transcriptional regulation of p21(WAF1/CIP1) in human prostate carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp1, but not Sp3, functions to mediate promoter activation by TGF-beta through canonical Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp1 phosphorylation by Erk 2 stimulates DNA binding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

A novel substrate for assays of gene expression using chloramphenicol acetyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Different Sp1 family members differentially affect transcription from the human elongation factor 1 A-1 gene promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

A role for Sp and helix-loop-helix transcription factors in the regulation of the human Id4 gene promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Involvement of the Sp3 transcription factor in induction of p21Cip1/WAF1 in keratinocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Sp1 and Sp3 regulate transcriptional activity of the facilitative glucose transporter isoform-3 gene in mammalian neuroblasts and trophoblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Activation of Sp1 and its functional co-operation with serum amyloid A-activating sequence binding factor in synoviocyte cells trigger synergistic action of interleukin-1 and interleukin-6 in serum amyloid A gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Glucose regulates the promoter activity of aldolase A and pyruvate kinase M2 via dephosphorylation of Sp1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Histone deacetylase inhibitor activates the WAF1/Cip1 gene promoter through the Sp1 sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Gene expression of the human glucagon-like peptide-1 receptor is regulated by Sp1 and Sp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

p21 is a universal inhibitor of cyclin kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

The mycotoxin fumonisin B1 transcriptionally activates the p21 promoter through a cis-acting element containing two Sp1 binding sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

The human POLD1 gene. Identification of an upstream activator sequence, activation by Sp1 and Sp3, and cell cycle regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

Protein kinase C alpha modulates growth and differentiation in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Cell cycle protein suppression and p21 induction in differentiating Caco-2 cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

p21--negative regulator of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Sp1-mediated transcriptional activation is repressed by Sp3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

p53-dependent and independent expression of p21 during cell growth, differentiation, and DNA damage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Nerve growth factor induces transcription of the p21 WAF1/CIP1 and cyclin D1 genes in PC12 cells by activating the Sp1 transcription factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1203900

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203900

1 reference

Dimensions Publication ID

24 September 2017

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1 reference