(Q40845701)

24 September 2017

1 reference

title

Human ether-a-gogo related gene (HERG) K+ channels as pharmacological targets: present and future implications (English)

1 reference

24 September 2017

M Taglialatela

1

1 reference

24 September 2017

P Castaldo

2

1 reference

24 September 2017

A Pannaccione

3

1 reference

24 September 2017

G Giorgio

4

1 reference

24 September 2017

L Annunziato

5

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24 September 2017

language of work or name

English

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publication date

1 June 1998

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24 September 2017

published in

Biochemical Pharmacology

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24 September 2017

volume

55

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24 September 2017

issue

11

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24 September 2017

page(s)

1741-1746

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Mechanisms and control of repolarization

24 September 2017

cites work

1 reference

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7 January 2021

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Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

7 January 2021

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A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome

7 January 2021

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SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

7 January 2021

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7 January 2021

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Structural motifs underlying voltage-dependent K+ channel function

7 January 2021

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The human delta1261 mutation of the HERG potassium channel results in a truncated protein that contains a subunit interaction domain and decreases the channel expression

7 January 2021

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Spectrum of HERG K+-channel dysfunction in an inherited cardiac arrhythmia

7 January 2021

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Four novel KVLQT1 and four novel HERG mutations in familial long-QT syndrome

7 January 2021

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A mutation in HERG associated with notched T waves in long QT syndrome.

7 January 2021

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Missense mutation in the pore region of HERG causes familial long QT syndrome

7 January 2021

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A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

7 January 2021

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The inward rectification mechanism of the HERG cardiac potassium channel

7 January 2021

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Molecular determinants for activation and inactivation of HERG, a human inward rectifier potassium channel.

7 January 2021

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Tissue and species distribution of mRNA for the IKr-like K+ channel, erg.

7 January 2021

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A novel inward-rectifying K+ current with a cell-cycle dependence governs the resting potential of mammalian neuroblastoma cells

7 January 2021

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A HERG-like K+ channel in rat F-11 DRG cell line: pharmacological identification and biophysical characterization

7 January 2021

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A novel role for HERG K+ channels: spike-frequency adaptation

7 January 2021

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The Drosophila erg K+ channel polypeptide is encoded by the seizure locus

7 January 2021

1 reference

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The seizure locus encodes the Drosophila homolog of the HERG potassium channel

7 January 2021

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Preliminary report: effect of encainide and flecainide on mortality in a randomized trial of arrhythmia suppression after myocardial infarction

7 January 2021

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Arrhythmia control by prolonging repolarization: the concept and its potential therapeutic impact

7 January 2021

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Effect of d-sotalol on mortality in patients with left ventricular dysfunction after recent and remote myocardial infarction. The SWORD Investigators. Survival With Oral d-Sotalol.

7 January 2021

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Temporal relation between long-lasting aftercontractions and action potentials in cat papillary muscles

7 January 2021

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K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

7 January 2021

1 reference

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Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

7 January 2021

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Molecular physiology and pharmacology of HERG. Single-channel currents and block by dofetilide.

7 January 2021

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

7 January 2021

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Ibutilide, a methanesulfonanilide antiarrhythmic, is a potent blocker of the rapidly activating delayed rectifier K+ current (IKr) in AT-1 cells. Concentration-, time-, voltage-, and use-dependent effects.

7 January 2021

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Mechanism of action potential prolongation by RP 58866 and its active enantiomer, terikalant. Block of the rapidly activating delayed rectifier K+ current, IKr.

7 January 2021

1 reference

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Cloned Human Inward Rectifier K + Channel as a Target for Class III Methanesulfonanilides

7 January 2021

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Specific IK1 blockade: a new antiarrhythmic mechanism? Effect of RP58866 on ventricular arrhythmias in rat, rabbit, and primate

7 January 2021

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Role of the ISK protein in the IminK channel complex

7 January 2021

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Terfenadine. A review of its pharmacodynamic properties and therapeutic efficacy

7 January 2021

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Cardiac actions of antihistamines

7 January 2021

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The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis

7 January 2021

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Cardiotoxic effect with convulsions in terfenadine overdose

7 January 2021

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Torsade de pointes after astemizole overdose.

7 January 2021

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Regulation of potassium channels by nonsedating antihistamines

7 January 2021

1 reference

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Cardiac electrophysiological actions of the histamine H1-receptor antagonists astemizole and terfenadine compared with chlorpheniramine and pyrilamine

7 January 2021

1 reference

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HERG, a primary human ventricular target of the nonsedating antihistamine terfenadine

7 January 2021

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Blockade of HERG channels expressed in Xenopus oocytes by the histamine receptor antagonists terfenadine and astemizole

7 January 2021

1 reference

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Loratadine. A reappraisal of its pharmacological properties and therapeutic use in allergic disorders

7 January 2021

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The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes

7 January 2021

1 reference

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Oxygen free radicals and calcium homeostasis in the heart

7 January 2021

1 reference

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Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species

7 January 2021

1 reference

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Myocardial consequences of reperfusion

7 January 2021

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Oxidative stress, glutamate, and neurodegenerative disorders

7 January 2021

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21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures

7 January 2021

1 reference

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Role of superoxide dismutase in ischemic brain injury: reduction of edema and infarction in transgenic mice following focal cerebral ischemia.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900002-1

The early events of oxygen and glucose deprivation: setting the scene for neuronal death?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900002-1

Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs

7 January 2021

1 reference

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17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900002-1

Long QT syndrome patients with mutations of the SCN5A and HERG genes have differential responses to Na+ channel blockade and to increases in heart rate. Implications for gene-specific therapy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900002-1

Ether-à-go-go encodes a voltage-gated channel permeable to K+ and Ca2+ and modulated by cAMP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2898%2900002-1

10.1016/S0006-2952(98)00002-1

7 January 2021

Identifiers

DOI

1 reference

24 September 2017

1 reference