(Q40852448)

24 September 2017

title

A predicted alpha -helix mediates targeting of the proprotein convertase PC1 to the regulated secretory pathway (English)

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24 September 2017

2

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24 September 2017

I Jutras

1

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24 September 2017

T L Reudelhuber

series ordinal

3

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24 September 2017

language of work or name

English

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publication date

1 December 2000

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Journal of Biological Chemistry

24 September 2017

number of pages

7

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based on heuristic

inferred from page(s)

published in

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24 September 2017

volume

275

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24 September 2017

issue

51

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24 September 2017

page(s)

40337-40343

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Furin: a mammalian subtilisin/Kex2p-like endoprotease involved in processing of a wide variety of precursor proteins

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Eukaryotic protein processing: endoproteolysis of precursor proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

The proprotein convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Two activation states of the prohormone convertase PC1 in the secretory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Differences in pH optima and calcium requirements for maturation of the prohormone convertases PC2 and PC3 indicates different intracellular locations for these events

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

7B2 facilitates the maturation of proPC2 in neuroendocrine cells and is required for the expression of enzymatic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Regulatory roles of the P domain of the subtilisin-like prohormone convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Structural elements that direct specific processing of different mammalian subtilisin-like prohormone convertases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

A C-terminal signal prevents secretion of luminal ER proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Sorting and storage during secretory granule biogenesis: looking backward and looking forward

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Carboxypeptidase E is a regulated secretory pathway sorting receptor: genetic obliteration leads to endocrine disorders in Cpe(fat) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Beta-cell lines derived from transgenic Cpe(fat)/Cpe(fat) mice are defective in carboxypeptidase E and proinsulin processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Mannose 6-phosphate receptors are sorted from immature secretory granules via adaptor protein AP-1, clathrin, and syntaxin 6-positive vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Distinct molecular mechanisms for protein sorting within immature secretory granules of pancreatic beta-cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Milieu-induced, selective aggregation of regulated secretory proteins in the trans-Golgi network

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

A protease processing site is essential for prorenin sorting to the regulated secretory pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

The integrity of the RRGDL sequence of the proprotein convertase PC1 is critical for its zymogen and C-terminal processing and for its cellular trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

The RGD motif and the C-terminal segment of proprotein convertase 1 are critical for its cellular trafficking but not for its intracellular binding to integrin alpha5beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Chromogranin B (secretogranin I) promotes sorting to the regulated secretory pathway of processing intermediates derived from a peptide hormone precursor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

The C-terminal region of carboxypeptidase E involved in membrane binding is distinct from the region involved with intracellular routing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Secretory granule content proteins and the luminal domains of granule membrane proteins aggregate in vitro at mildly acidic pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Mechanism of acidification of the trans-Golgi network (TGN). In situ measurements of pH using retrieval of TGN38 and furin from the cell surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Mutational analysis of PC1 (SPC3) in PC12 cells. 66-kDa PC1 is fully functional.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

Comparison of the Molecular Forms of the Kex2/Subtilisin‐Like Serine Proteases SPC2, SPC3, and Furin in Neuroendocrine Secretory Vesicles Reveals Differences in Carboxyl‐Terminus Truncation and Membrane Association

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M004757200

21 January 2018

Identifiers

DOI

10.1074/JBC.M004757200

1 reference

24 September 2017

1 reference