(Q40856888)

24 September 2017

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title

Lomefloxacin clinical pharmacokinetics (English)

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24 September 2017

C D Freeman

1

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24 September 2017

D P Nicolau

series ordinal

2

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24 September 2017

P P Belliveau

series ordinal

3

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24 September 2017

C H Nightingale

series ordinal

4

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24 September 2017

1 July 1993

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Clinical Pharmacokinetics

24 September 2017

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24 September 2017

25

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24 September 2017

6-19

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24 September 2017

1

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https://scigraph.springernature.com/pub.10.2165/00003088-199325010-00002

24 September 2017

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cites work

Usual and unusual antibacterial effects of quinolones

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12 December 2020

Mechanisms of quinolone resistance in Escherichia coli: characterization of nfxB and cfxB, two mutant resistance loci decreasing norfloxacin accumulation

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12 December 2020

In vitro and in vivo activity of NY-198, a new difluorinated quinolone

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12 December 2020

Investigations into the mechanism of action of the antibacterial agent norfloxacin

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12 December 2020

Selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes.

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12 December 2020

Comparative study with enoxacin and netilmicin in a pharmacodynamic model to determine importance of ratio of antibiotic peak concentration to MIC for bactericidal activity and emergence of resistance

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12 December 2020

Tissue penetration and pharmacokinetics of lomefloxacin following multiple doses

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12 December 2020

In-vitro activity of lomefloxacin in comparison with pefloxacin and ofloxacin

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12 December 2020

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents

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12 December 2020

Steady-state pharmacokinetics and sputum penetration of lomefloxacin in patients with chronic obstructive pulmonary disease and acute respiratory tract infections

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12 December 2020

In vitro activity of Bay 09867, a new quinoline derivative, compared with those of other antimicrobial agents

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12 December 2020

Lomefloxacin-induced modification of the kinetics of growth of gram-negative bacteria and susceptibility to phagocytic killing by human neutrophils.

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12 December 2020

Pharmacodynamics of a fluoroquinolone antimicrobial agent in a neutropenic rat model of Pseudomonas sepsis

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12 December 2020

Structure-epileptogenicity relationship of quinolones with special reference to their interaction with gamma-aminobutyric acid receptor sites

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12 December 2020

Structure-activity relationships of the fluoroquinolones

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12 December 2020

Comparative pharmacokinetic disposition of fluoroquinolones in the lung

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12 December 2020

Pharmacokinetics and safety of lomefloxacin following multiple doses

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12 December 2020

Comparative penetration of lomefloxacin and other quinolones into human phagocytes

1 reference

12 December 2020

Structure-activity relationships of antibacterial 6,7- and 7,8-disubstituted 1-alkyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acids

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12 December 2020

Influence of renal function on the pharmacokinetics of lomefloxacin compared with other fluoroquinolones

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12 December 2020

Mechanism of action of lomefloxacin

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12 December 2020

Kinetic interaction between theophylline and a newly developed quinolone, NY-198

1 reference

12 December 2020

In vitro activity of lomefloxacin, a new quinolone antimicrobial agent, in comparison with those of other agents

1 reference

12 December 2020

Lomefloxacin pharmacokinetics in subjects with normal and impaired renal function

1 reference

12 December 2020

Inhibition of Micrococcus luteus DNA gyrase by norfloxacin and 10 other quinolone carboxylic acids

1 reference

12 December 2020

Interaction of quinolones with the theophylline metabolism in man: investigations with lomefloxacin and pipemidic acid

1 reference

12 December 2020

Uptake of 3H-norfloxacin in methicillin-resistant Staphylococcus aureus

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12 December 2020

In vitro antimicrobial activity and postantibiotic effect of lomefloxacin, a new difluoroquinolone.

1 reference

12 December 2020

In vitro assessment of the postantibiotic effect of lomefloxacin against gram-positive and gram-negative pathogens

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12 December 2020

The crisis in antibiotic resistance

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12 December 2020

New structure-activity relationships of the quinolone antibacterials using the target enzyme. The development and application of a DNA gyrase assay

1 reference

12 December 2020

Multiple-dose pharmacokinetics of lomefloxacin: Rationale for once-a-day dosing

1 reference

12 December 2020

Penetration of lomefloxacin into human prostatic tissue

1 reference

12 December 2020

Emergence of ciprofloxacin-resistant coagulase-negative staphylococcal skin flora in immunocompromised patients receiving ciprofloxacin.

1 reference

12 December 2020

Bactericidal activity of lomefloxacin SC 47111 (NY-198) and ciprofloxacin against selected pathogens.

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12 December 2020

The emergence of resistance to ciprofloxacin during treatment of experimental Staphylococcus aureus endocarditis

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12 December 2020

Penetration of lomefloxacin into bronchial secretions following single and multiple oral administration

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12 December 2020

The fluoroquinolones: structures, mechanisms of action and resistance, and spectra of activity in vitro

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12 December 2020

In-vitro studies with ciprofloxacin, a new 4-quinolone compound.

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12 December 2020

Effect of antacid on absorption of the quinolone lomefloxacin

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12 December 2020

Killing and regrowth of bacteria in vitro: a review.

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12 December 2020

groEL and dnaK genes of Escherichia coli are induced by UV irradiation and nalidixic acid in an htpR+-dependent fashion

1 reference

12 December 2020

Intraprostatic distribution of lomefloxacin following multiple-dose administration

1 reference

12 December 2020

The pharmacokinetics of lomefloxacin in elderly patients with urinary tract infection following daily dosing with 400 mg.

1 reference

12 December 2020

Characterization of mechanisms of quinolone resistance in Pseudomonas aeruginosa strains isolated in vitro and in vivo during experimental endocarditis

1 reference

12 December 2020

Antimicrobial effects of lomefloxacin in vitro

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12 December 2020

Influence of lomefloxacin on the pharmacokinetics of theophylline

1 reference

12 December 2020

Enoxacin: a new fluoroquinolone.

1 reference

12 December 2020

A simple isocratic high-pressure liquid chromatographic assay of quinolones in serum.

1 reference

12 December 2020

Mechanisms of Fluoroquinolone Resistance in Staphylococcus aureus

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12 December 2020

The effect of multiple-dose oral lomefloxacin on theophylline metabolism in man

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12 December 2020

Pharmacokinetic disposition of quinolones in human body fluids and tissues

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12 December 2020

Pharmacokinetic study of lomefloxacin and its effect on the faecal flora of volunteers.

1 reference

12 December 2020

Determination of lomefloxacin in biological fluids by high-performance liquid chromatography and a microbiological method.

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12 December 2020

In vitro activity of lomefloxacin (SC-47111; NY-198), a difluoroquinolone 3-carboxylic acid, compared with those of other quinolones

1 reference

12 December 2020

The effects of quinolones on xanthine pharmacokinetics

1 reference

12 December 2020

Effect of lomefloxacin on theophylline pharmacokinetics

1 reference

12 December 2020

The mode of action of 4-quinolones and possible mechanisms of resistance

1 reference

12 December 2020

Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones

1 reference

12 December 2020

Bactericidal effect against Escherichia coli of nalidixic acid and four structurally related compounds

1 reference

12 December 2020

Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: the target of the drugs is DNA.

1 reference

12 December 2020

Pharmacokinetics of lomefloxacin in healthy volunteers: comparison of 400 milligrams once daily and 200 milligrams twice daily given orally for 5 days

1 reference

12 December 2020

Endogenous active efflux of norfloxacin in susceptible Escherichia coli

1 reference

12 December 2020

Nalidixic Acid: an Antibacterial Paradox

1 reference

12 December 2020

Development of resistance to nalidixic acid and the fluoroquinolones after the introduction of norfloxacin and ofloxacin

1 reference

12 December 2020

Antibacterial activity of lomefloxacin in a pharmacokinetic in vitro model

1 reference

12 December 2020

Postantibiotic Effect of Ciprofloxacin Compared with that of Five Other Quinolones

1 reference

12 December 2020

Inhibitory effects of quinolone antibacterial agents on gamma-aminobutyric acid binding to receptor sites in rat brain membranes

1 reference

12 December 2020

Comparative dose-effect relations at several dosing intervals for beta-lactam, aminoglycoside and quinolone antibiotics against gram-negative bacilli in murine thigh-infection and pneumonitis models.

1 reference

12 December 2020

Alterations in outer membrane proteins of Pseudomonas aeruginosa associated with selective resistance to quinolones

1 reference

12 December 2020

Pharmacokinetics and safety of single oral doses of lomefloxacin

1 reference

12 December 2020

Single-dose pharmacokinetics of lomefloxacin in patients with normal and impaired renal function

1 reference

12 December 2020

Pharmacokinetics of lomefloxacin in renally compromised patients

1 reference

12 December 2020

Plasmid-mediated 4-quinolone resistance: a real or apparent absence?

1 reference

12 December 2020

Comparative effects of ciprofloxacin and lomefloxacin on the oxidative metabolism of theophylline

1 reference

12 December 2020

Lomefloxacin: Microbiologic assessment and unique properties

1 reference

12 December 2020

In vitro activity of lomefloxacin (NY-198 or SC 47111).

1 reference

12 December 2020

Quinolone resistance-determining region in the DNA gyrase gyrA gene of Escherichia coli

1 reference

12 December 2020

Effect of food on absorption of lomefloxacin

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12 December 2020

Quinolone pharmacokinetics in the elderly

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12 December 2020

Methicillin-resistant strains of Staphylococcus aureus resistant to quinolones.

1 reference

12 December 2020

Lack of interaction between lomefloxacin and caffeine in normal volunteers

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12 December 2020

Genetic and physiological characterization of ciprofloxacin resistance in Pseudomonas aeruginosa PAO.

1 reference

12 December 2020

Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes

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12 December 2020

Concentrations of oral lomefloxacin in serum and bronchial mucosa

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12 December 2020

gyrA mutations in ciprofloxacin-resistant, methicillin-resistant Staphylococcus aureus from Indiana, Minnesota, and Tennessee

1 reference

12 December 2020

Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.

1 reference

12 December 2020

Pharmacokinetics of lomefloxacin in patients with cirrhosis

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12 December 2020

Pharmacokinetics and tissue penetration of orally administered lomefloxacin

1 reference

12 December 2020

Ciprofloxacin and the fluoroquinolones. New concepts on the mechanism of action and resistance.

1 reference

12 December 2020

Effect of schedule of administration on the therapeutic efficacy of penicillin; importance of the aggregate time penicillin remains at effectively bactericidal levels

1 reference

12 December 2020

Pharmacokinetics and tolerance of lomefloxacin after sequentially increasing oral doses

1 reference

12 December 2020

Drug interactions with fluoroquinolones

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12 December 2020

Impact of chemical structure on quinolone potency, spectrum and side effects

1 reference

12 December 2020

10.2165/00003088-199325010-00002

Identifiers

DOI

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Dimensions Publication ID

24 September 2017

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