(Q40857636)

English

The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist

scientific article published on January 2000

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scholarly article

1 reference

Europe PubMed Central

24 September 2017

The discovery of 4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1 ,5-a]-pyrimidine: a corticotropin-releasing factor (hCRF1) antagonist (English)

1 reference

Europe PubMed Central

24 September 2017

author name string

Gilligan PJ

1

1 reference

Europe PubMed Central

24 September 2017

Baldauf C

2

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Europe PubMed Central

24 September 2017

Cocuzza A

3

1 reference

Europe PubMed Central

24 September 2017

Chidester D

4

1 reference

Europe PubMed Central

24 September 2017

Zaczek R

5

1 reference

Europe PubMed Central

24 September 2017

Fitzgerald LW

6

1 reference

Europe PubMed Central

24 September 2017

McElroy J

7

1 reference

Europe PubMed Central

24 September 2017

Smith MA

8

1 reference

Europe PubMed Central

24 September 2017

Shen HS

9

1 reference

Europe PubMed Central

24 September 2017

Saye JA

10

1 reference

Europe PubMed Central

24 September 2017

Christ D

11

1 reference

Europe PubMed Central

24 September 2017

Trainor G

12

1 reference

Europe PubMed Central

24 September 2017

Robertson DW

13

1 reference

Europe PubMed Central

24 September 2017

Hartig P

14

1 reference

Europe PubMed Central

24 September 2017

language of work or name

0 references

publication date

1 January 2000

1 reference

Europe PubMed Central

24 September 2017

Bioorganic & Medicinal Chemistry

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Europe PubMed Central

24 September 2017

8

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Europe PubMed Central

24 September 2017

1

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24 September 2017

181-189

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24 September 2017

Characterization of rat hypothalamic corticotropin-releasing factor

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Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

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Corticotropin-releasing factor receptors are widely distributed within the rat central nervous system: an autoradiographic study

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Corticotropin-releasing hormone and inflammation.

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7 January 2021

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The hypothalamic-pituitary-adrenal axis and immune-mediated inflammation

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CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia

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CSF corticotropin-releasing factor-like immunoactivity in chronic pain patients with and without major depression

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Elevated CSF CRF in suicide victims

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Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients

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Psychiatric implications of basic and clinical studies with corticotropin-releasing factor

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ACTH and multisteroid responses to corticotropin-releasing factor in depressive illness: Relationship to multisteroid responses after ACTH stimulation and dexamethasone suppression☆

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Responses to corticotropin-releasing hormone in the hypercortisolism of depression and Cushing's disease. Pathophysiologic and diagnostic implications

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Hypercortisolism among socially subordinate wild baboons originates at the CNS level

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Synthesis and oral efficacy of a 4-(butylethylamino)pyrrolo[2,3-d]pyrimidine: a centrally active corticotropin-releasing factor1 receptor antagonist.

1 reference

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CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors.

1 reference

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Antidepressant-like effects of CP-154,526, a selective CRF1 receptor antagonist.

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Characterization of the behavioral profile of the non-peptide CRF receptor antagonist CP-154,526 in anxiety models in rodents. Comparison with diazepam and buspirone.

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Non-peptide corticotropin-releasing hormone antagonists: syntheses and structure-activity relationships of 2-anilinopyrimidines and -triazines

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7 January 2021

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Corticotropin-releasing hormone receptor antagonists: framework design and synthesis guided by ligand conformational studies

1 reference

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7 January 2021

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Synthesis, corticotropin-releasing factor receptor binding affinity, and pharmacokinetic properties of triazolo-, imidazo-, and pyrrolopyrimidines and -pyridines

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7 January 2021

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Some observations on the nutritional requirements of Eikenella corrodens ATCC 23834T grown in continuous culture

1 reference

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7 January 2021

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Pyrazolo[1,5-a]pyrimidine CRF-1 receptor antagonists.

1 reference

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7 January 2021

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Physiological and behavioral responses to corticotropin-releasing factor administration: is CRF a mediator of anxiety or stress responses?

1 reference

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7 January 2021

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Characterization of corticotropin-releasing factor receptor-mediated adenylate cyclase activity in the rat central nervous system

1 reference

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7 January 2021

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The contribution of behavioural studies to the neuropharmacology of anxiety

1 reference

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Corticotropin-releasing factor modulates defensive-withdrawal and exploratory behavior in rats

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Identifiers

10.1016/S0968-0896(99)00271-0

1 reference

Europe PubMed Central

24 September 2017

1 reference

Europe PubMed Central

24 September 2017

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