(Q40858247)

24 September 2017

4 references

6 August 2019

19 September 2019

9 October 2019

18 November 2020

Nephrotoxicity testing in vitro--what we know and what we need to know (English)

1 reference

pharmaceutical preparation

24 September 2017

1 reference

biomedical investigative technique

6 August 2019

1 reference

19 September 2019

1 reference

9 October 2019

1 reference

18 November 2020

Pfaller W

1

1 reference

PMCID

1533421

24 September 2017

Gstraunthaler G

series ordinal

2

1 reference

24 September 2017

1 April 1998

5 references

24 September 2017

6 August 2019

19 September 2019

9 October 2019

18 November 2020

11

1 reference

Environmental Health Perspectives

inferred from page(s)

published in

5 references

24 September 2017

6 August 2019

19 September 2019

9 October 2019

18 November 2020

106 Suppl 2

1 reference

24 September 2017

559-569

1 reference

Activation of heat shock factor by alkylating agents is triggered by glutathione depletion and oxidation of protein thiols

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Barrier function of epithelia

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

The application of nuclear magnetic resonance to the study of cellular physiology

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Sites of hormone action in the mammalian nephron

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Immunodissection: use of monoclonal antibodies to isolate specific types of renal cells

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Mutant isolation and gene transfer as tools in study of transport proteins

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Renal metabolism during normoxia, hypoxia, and ischemic injury

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Metabolic fuels along the nephron: pathways and intracellular mechanisms of interaction

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Use of extracellular matrix components for cell culture

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Epithelial cells in tissue culture

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

ATP and the regulation of renal cell function

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Characteristics of renal collecting tubule cells in primary culture

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Functional properties of glomerular cells in culture.

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Renal substrate metabolism

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Hormonal control of kidney functions at the cell level

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Role of Ca2+ in toxic cell killing

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Overview of epithelial polarity

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Glutathione conjugate mediated toxicities

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Renal proximal tubular cells in suspension or in primary culture as in vitro models to study nephrotoxicity

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Renal enzymes in kidney cells selected by D-valine medium

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Immortalization of epithelial cells

24 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Cell lines with extended in vitro growth potential from human renal proximal tubule: characterization, response to inducers, and comparison with established cell lines

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Immortalization and characterization of proximal tubule cells derived from kidneys of spontaneously hypertensive and normotensive rats

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Primary cultures of rabbit renal proximal tubule cells: I. Growth and biochemical characteristics

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

LLC-PK1 epithelia as a model for in vitro assessment of proximal tubular nephrotoxicity

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

In vitro nephrotoxicity of Russell's viper venom

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Oxidants and conductance of cultured epithelial cell monolayers: inositol phospholipid hydrolysis

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Metabolism of amino-acids: The synthesis of glutamine from glutamic acid and ammonia, and the enzymic hydrolysis of glutamine in animal tissues

25 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

HK-2: an immortalized proximal tubule epithelial cell line from normal adult human kidney

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Establishment of renal proximal tubule cell lines by targeted oncogenesis in transgenic mice using the L-pyruvate kinase-SV40 (T) antigen hybrid gene

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Polarity and transport properties of rabbit kidney proximal tubule cells on collagen IV-coated porous membranes

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Clinical value of fructose 1,6 bisphosphatase in monitoring renal proximal tubular injury

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Factors affecting the differentiation of epithelial transport and responsiveness to hormones

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Properties of a pure metabolically active glomerular preparation from rat kidneys. I. Isolation.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Occluding junctions in a renal cell line (LLC-PK1) with characteristics of proximal tubular cells.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Oxygen radicals alter the cell membrane potential in a renal cell line (LLC-PK1) with differentiated characteristics of proximal tubular cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Nephron segment and calcium as determinants of anoxic cell death in renal cultures

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences (IUPS).

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Gentamicin-induced increases in cytosolic calcium in pig kidney cells (LLC-PK1).

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Effects of diacylglycerols on LLC-PK1 renal epithelia: similarity to phorbol ester tumor promoters

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Cysteine conjugate beta-lyase of rat kidney cytosol: characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Neoplastic transformation of human epidermal keratinocytes by AD12-SV40 and Kirsten sarcoma viruses

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Identification of P-glycoprotein in renal brush border membranes.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Rat kidney proximal tubule cells in defined medium: the roles of cholera toxin, extracellular calcium and serum in cell growth and expression of gamma-glutamyltransferase.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Maintenance of proximal and distal cell functions in SV40-transformed tubular cell lines derived from rabbit kidney cortex.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Transepithelial transport of vinblastine by kidney-derived cell lines. Application of a new kinetic model to estimate in situ Km of the pump

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Transport of organic cations by kidney epithelial cell line LLC-PK1.

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Tissue culture of established renal cell lines

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Cadmium (Cd2+) disrupts intercellular junctions and actin filaments in LLC-PK1 cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Morphological and Biochemical Changes of LLC-PK<sub>1</sub>Cells during Adaptation to Glucose-Free Culture Conditions

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Increase in membrane fluidity modulates sodium-coupled uptakes and cyclic AMP synthesis by renal proximal tubular cells in primary culture

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Construction of an apparatus for perfusion cell cultures which enables in vitro experiments under organotypic conditions

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Activation of the growth arrest and DNA damage-inducible gene gadd 153 by nephrotoxic cysteine conjugates and dithiothreitol

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Mechanism of the nephrogenic repair response. Studies on proliferation and vimentin expression after 35S-1,2-dichlorovinyl-L-cysteine nephrotoxicity in vivo and in cultured proximal tubule epithelial cells

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Development and characterization of rabbit proximal tubular epithelial cell lines

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Isolation of a pure suspension of rat proximal tubules

15 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Retinoic acid modulates dome formation by MDCK cells in defined medium.

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

A 13C-NMR study on metabolic changes in proximal convoluted tubule cells induced by cadmium

19 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1533421

Retention of differentiated characteristics by cultures of defined rabbit kidney epithelia

19 August 2018

1 reference

12 December 2020

The role of glutathione conjugate metabolism and cysteine conjugate beta-lyase in the mechanism of S-cysteine conjugate toxicity in LLC-PK1 cells

1 reference

12 December 2020

Isolation and culture of HCO3- -secreting intercalated cells

1 reference

12 December 2020

Primary culture of rabbit proximal tubules as a cellular model to study nephrotoxicity of xenobiotics

1 reference

12 December 2020

Characterization of monoclonal antibodies to rabbit renal cortical cells

1 reference

12 December 2020

Characterization of primar cell cultures derived from rat renal proximal tubules

1 reference

12 December 2020

Hormonal regulation of gluconeogenesis in cultured proximal tubular cells: role of cytosolic calcium

1 reference

12 December 2020

Free radical-mediated membrane depolarization in renal and cardiac cells

1 reference

12 December 2020

Immunodissection of cortical and medullary thick ascending limb cells from rabbit kidney

1 reference

12 December 2020

Electrophysiology of proximal and distal tubules in the autoperfused dog kidney

1 reference

12 December 2020

Normal rat kidney proximal tubule cells in primary and multiple subcultures

1 reference

12 December 2020

Mercapturic acid formation in cultured opossum kidney cells

1 reference

12 December 2020

Regeneration of renal proximal tubule cells in primary culture following toxicant injury: response to growth factors

1 reference

12 December 2020

Metabolism of drugs by the kidney

1 reference

12 December 2020

Evaluation of nephrotoxicity in vitro using a suspension of highly purified porcine proximal tubular cells and characterization of the cells in primary culture

1 reference

12 December 2020

Cisplatin nephrotoxicity: in vitro studies with precision-cut rabbit renal cortical slices

1 reference

12 December 2020

Growth of functional primary cultures of kidney epithelial cells in defined medium

1 reference

12 December 2020

Cultures as epithelial models: porous-bottom culture dishes for studying transport and differentiation

1 reference

12 December 2020

Effect of albumin on the function of perfused rat kidney

1 reference

12 December 2020

Preparation and study of fragments of single rabbit nephrons

1 reference

12 December 2020

Consecutive use of hormonally defined serum-free media to establish highly differentiated human renal proximal tubule cells in primary culture

1 reference

12 December 2020

1 reference

12 December 2020

Serum-free cell culture: a unifying approach

1 reference

12 December 2020

Enzyme distribution along the nephron

1 reference

12 December 2020

Two types of K+ channels in the apical membrane of rabbit proximal tubule in primary culture

1 reference

12 December 2020

Distribution and characteristics of the occluding junctions in a monolayer of a cell line (MDCK) derived from canine kidney

1 reference

12 December 2020

Regulation of expression of the sodium-coupled hexose transporter in cultured LLC-PK1 epithelia

1 reference

12 December 2020

Porous-bottom dishes for culture of polarized cells

1 reference

12 December 2020

16 Preparation and characteristics of isolated kidney cells

1 reference

12 December 2020

Structure function correlation on rat kidney. Quantitative correlation of structure and function in the normal and injured rat kidney

1 reference

12 December 2020

Nephrotoxicant inhibition of renal proximal tubule cell regeneration

1 reference

12 December 2020

A role for fibroblast growth factor type-1 in nephrogenic repair. Autocrine expression in rat kidney proximal tubule epithelial cells in vitro and in the regenerating epithelium following nephrotoxic damage by S-(1,1,2,2-tetrafluoroethyl)-L-cysteine

1 reference

12 December 2020

Differential patterns of injury to the proximal tubule of renal cortical slices following in vitro exposure to mercuric chloride, potassium dichromate, or hypoxic conditions

1 reference

12 December 2020

Substrate utilization in the isolated perfused cortical thick ascending limb of rabbit nephron

1 reference

12 December 2020

Role of mitochondrial Ca2+ in the oxidative stress-induced dissipation of the mitochondrial membrane potential. Studies in isolated proximal tubular cells using the nephrotoxin 1,2-dichlorovinyl-L-cysteine

1 reference

12 December 2020

Differential inhibitory action of the fungal toxin orellanine on alkaline phosphatase isoenzymes

1 reference

12 December 2020

Primary culture of isolated tubule cells of defined segmental origin

1 reference

12 December 2020

Immunodissection of the human proximal nephron: flow sorting of S1S2S3, S1S2 and S3 proximal tubular cells.

1 reference

12 December 2020

Defined human renal tubular epithelia in culture: growth, characterization, and hormonal response

1 reference

12 December 2020

Monoclonal antibodies to rat renal tissue: an approach to the immunohistological analysis of the nephron-collecting duct system, and ultra-structural localization of antigens

1 reference

12 December 2020

Toxicity of the cysteine-S-conjugates and mercapturic acids of four structurally related difluoroethylenes in isolated proximal tubular cells from rat kidney. Uptake of the conjugates and activation to toxic metabolites

1 reference

12 December 2020

Signalling the molecular stress response to nephrotoxic and mutagenic cysteine conjugates: differential roles for protein synthesis and calcium in the induction of c-fos and c-myc mRNA in LLC-PK1 cells

1 reference

12 December 2020

Fusion of cultured dog kidney (MDCK) cells: I. Technique, fate of plasma membranes and of cell nuclei

1 reference

12 December 2020

Identifiers

0 references

1 reference

24 September 2017

1 reference

PMCID

1533421