(Q40860075)

24 September 2017

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title

Behavior in mice with targeted disruption of single genes (English)

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24 September 2017

1

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24 September 2017

Young KA

2

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24 September 2017

1 May 1998

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Neuroscience & Biobehavioral Reviews

24 September 2017

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24 September 2017

22

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24 September 2017

453-462

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24 September 2017

3

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Targeted gene modification for gene therapy of stem cells

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mammalian learning and memory studied by gene targeting.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

PKC gamma mutant mice exhibit mild deficits in spatial and contextual learning.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Modified hippocampal long-term potentiation in PKCγ-mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Reduced hippocampal long-term potentiation and context-specific deficit in associative learning in mGluR1 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Deletion of a DNA polymerase beta gene segment in T cells using cell type-specific gene targeting

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

The use of genetic "knockout" mice in behavioral endocrinology research

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Enhanced aggressive behavior in mice lacking 5-HT1B receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

A proposed test battery and constellations of specific behavioral paradigms to investigate the behavioral phenotypes of transgenic and knockout mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Effects on blood pressure and exploratory behaviour of mice lacking angiotensin II type-2 receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Atm-deficient mice: a paradigm of ataxia telangiectasia

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Sensory but not motor neuron deficits in mice lacking NT4 and BDNF

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired suckling

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Behavioral assessment of c-fos mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Effect of a null mutation of the c-fos proto-oncogene on sexual behavior of male mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Impaired spatial learning in alpha-calcium-calmodulin kinase II mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Deficient hippocampal long-term potentiation in alpha-calcium-calmodulin kinase II mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Reduction of morphine abstinence in mice with a mutation in the gene encoding CREB.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Severe impairment of spermatogenesis in mice lacking the CREM gene

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Parkinsonian-like locomotor impairment in mice lacking dopamine D2 receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

A targeted mutation of the D3 dopamine receptor gene is associated with hyperactivity in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Aggressive Behaviors of Transgenic Estrogen-receptor Knockout Male Mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Estrogen receptors are essential for female sexual receptivity

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Estrogen receptor function as revealed by knockout studies: neuroendocrine and behavioral aspects

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Fmr1 knockout mice: A model to study fragile X mental retardation

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

A defect in nurturing in mice lacking the immediate early gene fosB.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

A role for Fyn tyrosine kinase in the suckling behaviour of neonatal mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Increased fearfulness of Fyn tyrosine kinase deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Targeted deletion in astrocyte intermediate filament (Gfap) alters neuronal physiology

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Targeted disruption of the Hexa gene results in mice with biochemical and pathologic features of Tay-Sachs disease

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mice lacking both subunits of lysosomal beta-hexosaminidase display gangliosidosis and mucopolysaccharidosis

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mouse models of Tay-Sachs and Sandhoff diseases differ in neurologic phenotype and ganglioside metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Hippocampal long-term potentiation is normal in heme oxygenase-2 mutant mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Effects of an Igf1 gene null mutation on mouse reproduction

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Ataxia and epileptic seizures in mice lacking type 1 inositol 1,4,5-trisphosphate receptor.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Aggressive behavior and altered amounts of brain serotonin and norepinephrine in mice lacking MAOA

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Impairment of hippocampal mossy fiber LTD in mice lacking mGluR2.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Abnormal avoidance learning in mice lacking functional high-affinity nicotine receptor in the brain

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Forward and reverse genetic approaches to behavior in the mouse

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Life without neuropeptide Y

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Disruption of the neurotrophin-3 receptor gene trkC eliminates la muscle afferents and results in abnormal movements

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Luteinizing hormone deficiency and female infertility in mice lacking the transcription factor NGFI-A (Egr-1)

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Reduced hippocampal LTP and spatial learning in mice lacking NMDA receptor epsilon 1 subunit

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Severe sensory and sympathetic deficits in mice lacking neurotrophin-3.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Oxytocin is required for nursing but is not essential for parturition or reproductive behavior

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Pleiotropy in microdeletion syndromes: neurologic and spermatogenic abnormalities in mice homozygous for the p6H deletion are likely due to dysfunction of a single gene

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mutant mice lacking the gamma isoform of protein kinase C show decreased behavioral actions of ethanol and altered function of gamma-aminobutyrate type A receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Disruption of the compacted myelin sheath of axons of the central nervous system in proteolipid protein-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Generation and characterization of mutant mice lacking ryanodine receptor type 3.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Normal spatial learning despite regional inhibition of LTP in mice lacking Thy-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Abnormal behavior and neurotransmissions of tenascin gene knockout mouse.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Dopamine-deficient mice are severely hypoactive, adipsic, and aphagic

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Transgenic and knock-out mice: models of neurological disease.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Gene Targeting in ES Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Positive genetic selection for gene disruption in mammalian cells by homologous recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Targeted replacement of the homeobox gene Hox-3.1 by the Escherichia coli lacZ in mouse chimeric embryos

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Gene knock-out technology: a methodological overview for the interested novice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Inducible gene targeting in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Control of memory formation through regulated expression of a CaMKII transgene

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Neural systems and the inhibitory modulation of agonistic behavior: A comparison of mammalian species

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Reduced aggressive behaviour in mice with targeted disruption of the oxytocin gene.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Inhibition of neuronal nitric oxide synthase increases aggressive behavior in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Aggressive behavior in male mice lacking the gene for neuronal nitric oxide synthase requires testosterone.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

The role of calcium-calmodulin kinase II in three forms of synaptic plasticity

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Nitric oxide, a novel neuronal messenger

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Transient nitric oxide synthase neurons in embryonic cerebral cortical plate, sensory ganglia, and olfactory epithelium.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Endothelial NOS and the blockade of LTP by NOS inhibitors in mice lacking neuronal NOS.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obese

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Thermoregulatory and metabolic phenotypes of mice lacking noradrenaline and adrenaline

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Cellular responses to psychomotor stimulant and neuroleptic drugs are abnormal in mice lacking the D1 dopamine receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Behavioral effects of estrogen receptor gene disruption in male mice

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

An evaluation of the nitric oxide/cGMP/cGMP-dependent protein kinase cascade in the induction of cerebellar long-term depression in culture.

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Mice deficient in ubiquitous mitochondrial creatine kinase are viable and fertile

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Carbon monoxide: a putative neural messenger

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

Rescue of neurophysiological phenotype seen in PrP null mice by transgene encoding human prion protein

1 reference

https://api.crossref.org/works/10.1016%2FS0149-7634%2897%2900053-5

7 January 2021

10.1016/S0149-7634(97)00053-5

Identifiers

DOI

1 reference

24 September 2017

1 reference

PubMed ID

9579332