(Q40862150)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Topoisomerase II is required for mitoxantrone to signal nuclear factor kappa B activation in HL60 cells (English)

1 reference

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9 November 2019

3

1 reference

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9 November 2019

author name string

M P Boland

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

K A Fitzgerald

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 August 2000

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

9 November 2019

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

275

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

25231-25238

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10940316%20AND%20SRC:MED&resulttype=core&format=json

Lipid peroxidation is involved in the activation of NF-kappaB by tumor necrosis factor but not interleukin-1 in the human endothelial cell line ECV304. Lack of involvement of H2O2 in NF-kappaB activation by either cytokine in both primary and transf

9 November 2019

cites work

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Ionizing radiation induces expression and binding activity of the nuclear factor kappa B

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Function and activation of NF-kappa B in the immune system

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NF-kappa B: ten years after

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Ceramide activates NFkappaB by inducing the processing of p105.

21 January 2018

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NF-kappa B subunit regulation in nontransformed CD4+ T lymphocytes

21 January 2018

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I kappa B proteins: structure, function and regulation

21 January 2018

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Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

21 January 2018

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Identification of the receptor component of the IkappaBalpha-ubiquitin ligase

21 January 2018

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NF-kappaB activation: the I kappaB kinase revealed?

21 January 2018

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IKAP is a scaffold protein of the IkappaB kinase complex

21 January 2018

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

21 January 2018

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Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

21 January 2018

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Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?

21 January 2018

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

21 January 2018

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Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

21 January 2018

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Redox regulation of NF-kappa B activation

21 January 2018

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Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals

21 January 2018

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A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

21 January 2018

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Lack of involvement of reactive oxygen in the cytotoxicity of mitoxantrone, CI941 and ametantrone in MCF-7 cells: comparison with doxorubicin

21 January 2018

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21 January 2018

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Biochemical and pharmacological properties of p170 and p180 forms of topoisomerase II.

21 January 2018

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Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

21 January 2018

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Human topoisomerase II alpha is phosphorylated in a cell-cycle phase-dependent manner by a proline-directed kinase.

21 January 2018

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DNA sequence selectivity of topoisomerases and topoisomerase poisons.

21 January 2018

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Reduced activity of topoisomerase II in an Adriamycin-resistant human stomach-adenocarcinoma cell line

21 January 2018

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Murine transgenic cells lacking DNA topoisomerase IIbeta are resistant to acridines and mitoxantrone: analysis of cytotoxicity and cleavable complex formation.

21 January 2018

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Mitoxantrone resistance in HL-60 leukemia cells: reduced nuclear topoisomerase II catalytic activity and drug-induced DNA cleavage in association with reduced expression of the topoisomerase II beta isoform

21 January 2018

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Association of human DNA topoisomerase IIalpha with mitotic chromosomes in mammalian cells is independent of its catalytic activity

21 January 2018

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21 January 2018

Caspases: enemies within

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Cellular pharmacology of mitoxantrone in p-glycoprotein-positive and -negative human myeloid leukemic cell lines.

21 January 2018

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21 January 2018

Dexrazoxane (ICRF-187).

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DNA topoisomerase II rescue by catalytic inhibitors: a new strategy to improve the antitumor selectivity of etoposide

21 January 2018

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Merbarone inhibits the catalytic activity of human topoisomerase IIalpha by blocking DNA cleavage

21 January 2018

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DNA damage signals induction of fas ligand in tumor cells.

21 January 2018

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Activate NF-kappa B or die?

21 January 2018

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

21 January 2018

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Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB.

21 January 2018

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Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells

21 January 2018

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Transcription factor NF-kappa B is activated by photosensitization generating oxidative DNA damages

21 January 2018

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Microsomal lipid peroxidation induced by adriamycin, epirubicin, daunorubicin and mitoxantrone: a comparative study

21 January 2018

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Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

21 January 2018

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Physiological regulation of eukaryotic topoisomerase II

21 January 2018

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Casein kinase II stabilizes the activity of human topoisomerase IIalpha in a phosphorylation-independent manner

21 January 2018

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Increased camptothecin toxicity induced in mammalian cells expressing Saccharomyces cerevisiae DNA topoisomerase I

21 January 2018

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Antagonistic effect of the cardioprotector (+)-1,2-bis(3,5-dioxopiperazinyl-1-yl)propane (ICRF-187) on DNA breaks and cytotoxicity induced by the topoisomerase II directed drugs daunorubicin and etoposide (VP-16)

21 January 2018

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Complementation of temperature-sensitive topoisomerase II mutations in Saccharomyces cerevisiae by a human TOP2 beta construct allows the study of topoisomerase II beta inhibitors in yeast

21 January 2018

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The inhibitors of apoptosis (IAPs) and their emerging role in cancer

21 January 2018

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