(Q40864137)

English

Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002).

scientific article published on September 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

24 September 2017

Suppression of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated aryl hydrocarbon receptor transformation and CYP1A1 induction by the phosphatidylinositol 3-kinase inhibitor 2-(4-morpholinyl)-8-phenyl-4H-1- benzopyran-4-one (LY294002). (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

M Guo

1

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

A Joiakim

2

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Europe PubMed Central

PubMed publication ID

24 September 2017

J J Reiners

3

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Europe PubMed Central

PubMed publication ID

24 September 2017

language of work or name

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publication date

1 September 2000

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Europe PubMed Central

PubMed publication ID

24 September 2017

Biochemical Pharmacology

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Europe PubMed Central

PubMed publication ID

24 September 2017

60

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Europe PubMed Central

PubMed publication ID

24 September 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

635-642

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

The aryl hydrocarbon receptor complex

1 reference

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Ah receptor signaling pathways

1 reference

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Drug-metabolizing enzymes in ligand-modulated transcription

1 reference

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Substituted flavones as aryl hydrocarbon (Ah) receptor agonists and antagonists

1 reference

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Analysis of structural requirements for Ah receptor antagonist activity: ellipticines, flavones, and related compounds

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Identification of 3'-methoxy-4'-nitroflavone as a pure aryl hydrocarbon (Ah) receptor antagonist and evidence for more than one form of the nuclear Ah receptor in MCF-7 human breast cancer cells

1 reference

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Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling

1 reference

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Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B

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Thrombospondin signaling of focal adhesion disassembly requires activation of phosphoinositide 3-kinase

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Mitogenic signaling of insulin-like growth factor I in MCF-7 human breast cancer cells requires phosphatidylinositol 3-kinase and is independent of mitogen-activated protein kinase.

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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A synthetic inhibitor of the mitogen-activated protein kinase cascade

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Phosphatidylinositol-3 kinase is necessary for 12-O-tetradecanoylphorbol-13-acetate-induced cell transformation and activated protein 1 activation

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Transformation of human breast epithelial cells by c-Ha-ras oncogene

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Downregulation of aryl hydrocarbon receptor function and cytochrome P450 1A1 induction by expression of Ha-ras oncogenes

1 reference

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Regulation of surface-differentiation molecules by epidermal growth factor, transforming growth factor alpha, and hydrocortisone in human mammary epithelial cells transformed by an activated c-Ha-ras proto-oncogene

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

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Use of gel retardation to analyze protein-DNA interactions upstream of CYPIA1 gene

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Suppression of cell cycle progression by flavonoids: dependence on the aryl hydrocarbon receptor

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Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor

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7 January 2021

Growth inhibitory and antimitogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in T47D human breast cancer cells

1 reference

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7 January 2021

Mechanism of inhibition of MDA-MB-468 breast cancer cell growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin

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7 January 2021

Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on growth factor expression in the human breast cancer cell line MCF-7.

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The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes

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PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase

1 reference

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7 January 2021

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10.1016/S0006-2952(00)00379-8

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

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