(Q40870320)

English

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase.

scientific article published on September 2000

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

author name string

Annerén C

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Reedquist KA

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

Bos JL

3

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8 November 2019

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publication date

1 September 2000

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8 November 2019

Journal of Biological Chemistry

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

275

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8 November 2019

37

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8 November 2019

29153-29161

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PubMed publication ID

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8 November 2019

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Nerve growth factor prevents the death and stimulates the neuronal differentiation of clonal PC12 pheochromocytoma cells in serum-free medium

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Rap1 mediates sustained MAP kinase activation induced by nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

A ras-related gene with transformation suppressor activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Cloning of BSK, a murine FRK homologue with a specific pattern of tissue distribution.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

iyk, a novel intracellular protein tyrosine kinase differentially expressed in the mouse mammary gland and intestine

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Cloning of FRK, a novel human intracellular SRC-like tyrosine kinase-encoding gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

A newly identified tyrosine kinase is preferentially expressed in the gastrointestinal tract

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Mutation of C-terminal tyrosine residues Y497/Y504 of the Src-family member Bsk/Iyk decreases NIH3T3 cell proliferation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

TrkA cross-linking mimics neuronal responses to nerve growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Two species of human CRK cDNA encode proteins with distinct biological activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Rapid Ca2+-mediated activation of Rap1 in human platelets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Integrin signalling and tyrosine phosphorylation: just the FAKs?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Role of Crk oncogene product in physiologic signaling.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Overexpression of the trk tyrosine kinase rapidly accelerates nerve growth factor-induced differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

The cytoplasmic raf oncogene induces a neuronal phenotype in PC12 cells: a potential role for cellular raf kinases in neuronal growth factor signal transduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

GTPase-deficient G alpha 16 and G alpha q induce PC12 cell differentiation and persistent activation of cJun NH2-terminal kinases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Mitogen-activated protein kinase activation is insufficient for growth factor receptor-mediated PC12 cell differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Biochemical characterization of C3G: an exchange factor that discriminates between Rap1 and Rap2 and is not inhibited by Rap1A(S17N).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

SH2 domains recognize specific phosphopeptide sequences

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Focal adhesion kinase in integrin signaling

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Activation of Rho-dependent cell spreading and focal adhesion biogenesis by the v-Crk adaptor protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Thermodynamic and kinetic characterization of the interaction between the Ras binding domain of AF6 and members of the Ras subfamily

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Association of Krev-1/rap1a with Krit1, a novel ankyrin repeat-containing protein encoded by a gene mapping to 7q21-22

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Identification of Nore1 as a potential Ras effector

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Activation of the small GTPase Ral in platelets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Nerve growth factor-induced process formation by cultured rat pheochromocytoma cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Differentiation of PC12 phaeochromocytoma cells induced by v-src oncogene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M003926200

21 January 2018

Identifiers

10.1074/JBC.M003926200

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10878015%20AND%20SRC:MED&resulttype=core&format=json

8 November 2019

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