(Q40878496)

24 September 2017

title

Grancalcin (GCA) modulates Toll-like receptor 9 (TLR9) mediated signaling through its direct interaction with TLR9. (English)

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24 September 2017

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Tae Whan Kim

1

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24 September 2017

Seunghee Hong

2

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24 September 2017

Amjad H Talukder

3

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24 September 2017

Virginia Pascual

4

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24 September 2017

Yong-Jun Liu

5

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24 September 2017

language of work or name

English

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publication date

9 December 2015

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European Journal of Immunology

24 September 2017

published in

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24 September 2017

volume

46

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24 September 2017

issue

3

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24 September 2017

page(s)

712-724

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Plasmacytoid dendritic cells: sensing nucleic acids in viral infection and autoimmune diseases.

24 September 2017

cites work

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A protein associated with Toll-like receptor (TLR) 4 (PRAT4A) is required for TLR-dependent immune responses

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The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

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UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

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Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

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Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.

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The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.

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Immune cell activation by bacterial CpG-DNA through myeloid differentiation marker 88 and tumor necrosis factor receptor-associated factor (TRAF)6.

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A Toll-like receptor recognizes bacterial DNA

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Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction

21 January 2018

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Phospholipid scramblase 1 regulates Toll-like receptor 9-mediated type I interferon production in plasmacytoid dendritic cells

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Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

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Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells

21 January 2018

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Biochemical characterization of the penta-EF-hand protein grancalcin and identification of L-plastin as a binding partner

21 January 2018

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Structures, functions and molecular evolution of the penta-EF-hand Ca2+-binding proteins

21 January 2018

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Isolation and characterization of grancalcin, a novel 28 kDa EF-hand calcium-binding protein from human neutrophils

21 January 2018

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Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes

21 January 2018

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The PEF family proteins sorcin and grancalcin interact in vivo and in vitro

21 January 2018

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Crystal structure of calcium-free human sorcin: a member of the penta-EF-hand protein family

21 January 2018

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Structure of apoptosis-linked protein ALG-2: insights into Ca2+-induced changes in penta-EF-hand proteins

21 January 2018

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Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner

21 January 2018

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Crystal structure of human grancalcin, a member of the penta-EF-hand protein family

21 January 2018

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The enigmatic plasmacytoid T cells develop into dendritic cells with interleukin (IL)-3 and CD40-ligand

21 January 2018

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The structure of calpain.

21 January 2018

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Granulocyte function in grancalcin-deficient mice

21 January 2018

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Characterization of murine grancalcin specifically expressed in leukocytes and its possible role in host defense against bacterial infection

21 January 2018

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Flow cytometric sorting and biochemical characterization of the late endosomal rab7-containing compartment.

21 January 2018

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Plasmacytoid monocytes migrate to inflamed lymph nodes and produce large amounts of type I interferon

21 January 2018

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Leukemic plasmacytoid dendritic cells share phenotypic and functional features with their normal counterparts

21 January 2018

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7 January 2021

An ELISA for grancalcin, a novel cytosolic calcium-binding protein present in leukocytes

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545567

7 January 2021

Modulation of intracellular Ca2+ levels in the heart by sorcin and FKBP12, two accessory proteins of ryanodine receptors

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545567

7 January 2021

The role of grancalcin in adhesion of neutrophils

1 reference

https://api.crossref.org/works/10.1002%2FEJI.201545567

7 January 2021

Identifiers

DOI

10.1002/EJI.201545567

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24 September 2017

1 reference