(Q40879522)

English

Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188.

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Europe PubMed Central

PubMed publication ID

24 September 2017

Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel alpha1A subunit. Role of L-type Met1188. (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

author name string

Sinnegger MJ

1

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Europe PubMed Central

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24 September 2017

Wang Z

2

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Europe PubMed Central

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24 September 2017

Grabner M

3

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Europe PubMed Central

PubMed publication ID

24 September 2017

Hering S

4

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Striessnig J

5

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Europe PubMed Central

PubMed publication ID

24 September 2017

Glossmann H

6

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24 September 2017

Mitterdorfer J

7

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24 September 2017

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publication date

1 October 1997

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24 September 2017

Journal of Biological Chemistry

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24 September 2017

272

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24 September 2017

44

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Europe PubMed Central

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24 September 2017

27686-27693

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

Structure and function of voltage-gated ion channels

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Exocytotic Ca2+ channels in mammalian central neurons

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Molecular basis for Ca2+ channel diversity

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Primary structure and functional expression of the cardiac dihydropyridine-sensitive calcium channel

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Cloning of the alpha 1 subunit of a voltage-dependent calcium channel expressed in pancreatic beta cells

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Receptor sites for Ca2+ channel antagonists

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Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state

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Calcium channels in vertebrate cells

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Dihydropyridine receptor of L-type Ca2+ channels: identification of binding domains for [3H](+)-PN200-110 and [3H]azidopine within the alpha 1 subunit.

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Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

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Coordination of Ca2+ by the pore region glutamates is essential for high-affinity dihydropyridine binding to the cardiac Ca2+ channel alpha 1 subunit.

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Molecular localization of regions in the L-type calcium channel critical for dihydropyridine action

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Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4-dihydropyridine sensitivity

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Primary structure and functional expression from complementary DNA of a brain calcium channel

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Distinctive biophysical and pharmacological properties of class A (BI) calcium channel alpha 1 subunits

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Transfer of high sensitivity for benzothiazepines from L-type to class A (BI) calcium channels

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DNA sequencing with chain-terminating inhibitors

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Primary structure of the beta subunit of the DHP-sensitive calcium channel from skeletal muscle

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Sequence and expression of mRNAs encoding the alpha 1 and alpha 2 subunits of a DHP-sensitive calcium channel

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Calcium channels from Cyprinus carpio skeletal muscle.

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Voltage-dependent modulation of Ca channel current in heart cells by Bay K8644.

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Molecular Determinants of High Affinity Phenylalkylamine Block of L-type Calcium Channels

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Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.

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Pursuing the structure and function of voltage-gated channels

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Antagonists of neuronal calcium channels: structure, function, and therapeutic implications

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Familial hemiplegic migraine and episodic ataxia type-2 are caused by mutations in the Ca2+ channel gene CACNL1A4

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Autosomal dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the alpha 1A-voltage-dependent calcium channel

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The naming of voltage-gated calcium channels

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Calcium binding in the pore of L-type calcium channels modulates high affinity dihydropyridine binding

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Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels

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Molecular determinants of high affinity dihydropyridine binding in L-type calcium channels

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Depolarization-stimulated 42K+ efflux in rat aorta is calcium- and cellular volume-dependent

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Voltage- and use-dependent modulation of cardiac calcium channels by the dihydropyridine (+)-202-791

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Identification of benz(othi)azepine-binding regions within L-type calcium channel alpha1 subunits

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L-type calcium channels: binding domains for dihydropyridines and benzothiazepines are located in close proximity to each other

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Structural model of the outer vestibule and selectivity filter of the Shaker voltage-gated K+ channel

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Identifiers

10.1074/JBC.272.44.27686

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 September 2017

ResearchGate publication ID

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