(Q40880707)

24 September 2017

Lamivudine (3TC) phosphorylation and drug interactions in vitro (English)

1 reference

24 September 2017

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1 reference

Kewn S

1

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24 September 2017

Veal GJ

2

1 reference

24 September 2017

Hoggard PG

3

1 reference

24 September 2017

Barry MG

4

1 reference

24 September 2017

Back DJ

5

1 reference

24 September 2017

language of work or name

English

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publication date

1 September 1997

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24 September 2017

Biochemical Pharmacology

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24 September 2017

54

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24 September 2017

5

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24 September 2017

589-595

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(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

24 September 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

A phase I/II study of 2'-deoxy-3'-thiacytidine (lamivudine) in patients with advanced human immunodeficiency virus infection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

3'-Azido-3'-deoxythymidine triphosphate as an inhibitor and substrate of purified human immunodeficiency virus reverse transcriptase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Favorable interaction of beta-L(-) nucleoside analogues with clinically approved anti-HIV nucleoside analogues for the treatment of human immunodeficiency virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

High-level resistance to (-) enantiomeric 2'-deoxy-3'-thiacytidine in vitro is due to one amino acid substitution in the catalytic site of human immunodeficiency virus type 1 reverse transcriptase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

A trial comparing nucleoside monotherapy with combination therapy in HIV-infected adults with CD4 cell counts from 200 to 500 per cubic millimeter. AIDS Clinical Trials Group Study 175 Study Team

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Potential mechanism for sustained antiretroviral efficacy of AZT-3TC combination therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Drug interactions with zidovudine phosphorylation in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Interaction between lamivudine (3TC) and other nucleoside analogues for intracellular phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Differential phosphorylation of azidothymidine, dideoxycytidine, and dideoxyinosine in resting and activated peripheral blood mononuclear cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Pharmacokinetics of lamivudine administered alone and with trimethoprim-sulfamethoxazole

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

The intracellular phosphorylation of (-)-2'-deoxy-3'-thiacytidine (3TC) and the incorporation of 3TC 5'-monophosphate into DNA by HIV-1 reverse transcriptase and human DNA polymerase gamma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Cellular metabolism of (−) enantiomeric 2′-deoxy-3′-thiacytidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Pharmacokinetics of 2',3'-dideoxycytidine in patients with AIDS and related disorders.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Pharmacokinetics of didanosine in patients with acquired immunodeficiency syndrome or acquired immunodeficiency syndrome-related complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

2',3'-didehydro-3'-deoxythymidine (d4T) in patients with AIDS or AIDS-related complex: a phase I trial

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Regulation of phosphorylation of deoxycytidine and 2',2'-difluorodeoxycytidine (gemcitabine); effects of cytidine 5'-triphosphate and uridine 5'-triphosphate in relation to chemosensitivity for 2',2'-difluorodeoxycytidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Affinity of the antiviral enantiomers of oxathiolane cytosine nucleosides for human 2'-deoxycytidine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Mitochondrial myopathy caused by long-term zidovudine therapy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

AZT causes tissue-specific inhibition of mitochondrial bioenergetic function.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Cellular pharmacology of 2',3'-dideoxy-2',3'-didehydrothymidine, a nucleoside analog active against human immunodeficiency virus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Enzymatic phosphorylation and pyrophosphorylation of 2',3'-dideoxyadenosine-5'-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2',3'-dideoxyinosine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

Effects of drugs on 2',3'-dideoxy-2',3'-didehydrothymidine phosphorylation in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2897%2900189-5

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0006-2952(97)00189-5

1 reference

24 September 2017

1 reference