(Q40886593)

24 September 2017

title

Transcriptional activation by the Ewing's sarcoma (EWS) oncogene can be cis-repressed by the EWS RNA-binding domain (English)

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24 September 2017

Li KK

1

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24 September 2017

Lee KA

series ordinal

2

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24 September 2017

language of work or name

English

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publication date

1 July 2000

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Journal of Biological Chemistry

24 September 2017

published in

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24 September 2017

volume

275

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24 September 2017

issue

30

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24 September 2017

page(s)

23053-23058

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The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

24 September 2017

cites work

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EWS and ATF-1 gene fusion induced by t(12;22) translocation in malignant melanoma of soft parts

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Oncogenic EWS-Fli1 interacts with hsRPB7, a subunit of human RNA polymerase II.

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A topogenic role for the oncogenic N-terminus of TLS: nucleolar localization when transcription is inhibited

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Tyrosine kinase Pyk2 mediates G-protein-coupled receptor regulation of the Ewing sarcoma RNA-binding protein EWS

21 January 2018

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EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

21 January 2018

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The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS

21 January 2018

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TLS (Translocated-in-Liposarcoma) Is a High-Affinity Interactor for Steroid, Thyroid Hormone, and Retinoid Receptors

21 January 2018

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Identification of a cyclic-AMP-responsive element within the rat somatostatin gene

21 January 2018

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Regulation of transcription by cyclic AMP-dependent protein kinase

21 January 2018

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The cellular transcription factor CREB corresponds to activating transcription factor 47 (ATF-47) and forms complexes with a group of polypeptides related to ATF-43.

21 January 2018

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Conserved structures and diversity of functions of RNA-binding proteins

21 January 2018

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The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription

21 January 2018

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The prooncoprotein EWS binds calmodulin and is phosphorylated by protein kinase C through an IQ domain

21 January 2018

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Genomic structure of the EWS gene and its relationship to EWSR1, a site of tumor-associated chromosome translocation

21 January 2018

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Purified recombinant Fmrp exhibits selective RNA binding as an intrinsic property of the fragile X mental retardation protein

21 January 2018

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21 January 2018

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Control of pre-mRNA accumulation by the essential yeast protein Nrd1 requires high-affinity transcript binding and a domain implicated in RNA polymerase II association

21 January 2018

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hnRNP U inhibits carboxy-terminal domain phosphorylation by TFIIH and represses RNA polymerase II elongation

21 January 2018

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NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation

21 January 2018

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C-terminal domain (CTD) of RNA-polymerase II and N-terminal segment of the human TATA binding protein (TBP) can mediate remote and proximal transcriptional activation, respectively

21 January 2018

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The VP16 transcription activation domain is functional when targeted to a promoter-proximal RNA sequence

21 January 2018

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A specific isoform of hnRNP D interacts with DNA in the LR1 heterodimer: canonical RNA binding motifs in a sequence-specific duplex DNA binding protein

21 January 2018

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trans-Activation by the hnRNP K protein involves an increase in RNA synthesis from the reporter genes

21 January 2018

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Heterogeneous nuclear ribonucleoprotein D0B is a sequence-specificDNA-binding protein

21 January 2018

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The N-terminal domain of human TAFII68 displays transactivation and oncogenic properties

21 January 2018

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The desmoplastic small round cell tumor t(11;22) translocation produces EWS/WT1 isoforms with differing oncogenic properties

21 January 2018

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Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

21 January 2018

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A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP

21 January 2018

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EWS-Fli1 antisense oligodeoxynucleotide inhibits proliferation of human Ewing's sarcoma and primitive neuroectodermal tumor cells

21 January 2018

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Inhibition of apoptosis by normal and aberrant Fli-1 and erg proteins involved in human solid tumors and leukemias

21 January 2018

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Transcriptional regulation by CREB and its relatives

21 January 2018

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Protein-kinase-A-dependent activator in transcription factor CREB reveals new role for CREM repressors

21 January 2018

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In vitro phosphorylation studies of a conserved region of the transcription factor ATF1.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M002961200

1 reference

24 September 2017

1 reference