(Q40893778)

24 September 2017

title

Mechanisms of enhancement of cytotoxicity in etoposide and ionising radiation-treated cells by the protein kinase inhibitor wortmannin (English)

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24 September 2017

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Boulton S

1

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24 September 2017

Kyle S

series ordinal

2

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24 September 2017

Durkacz BW

series ordinal

3

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24 September 2017

language of work or name

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1 March 2000

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European Journal of Cancer

24 September 2017

published in

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24 September 2017

volume

36

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24 September 2017

issue

4

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24 September 2017

page(s)

535-541

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Cellular determinants of sensitivity and resistance to DNA topoisomerase inhibitors

24 September 2017

cites work

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7 January 2021

DNA-dependent protein kinase activity is absent in xrs-6 cells: implications for site-specific recombination and DNA double-strand break repair

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7 January 2021

DNA-PK: at the cross-roads of biochemistry and genetics

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Menage à trois: double strand break repair, V(D)J recombination and DNA-PK.

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7 January 2021

Molecular and biochemical characterization of xrs mutants defective in Ku80.

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7 January 2021

Wortmannin inhibits repair of DNA double-strand breaks in irradiated normal human cells.

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7 January 2021

End-joining of free radical-mediated DNA double-strand breaks in vitro is blocked by the kinase inhibitor wortmannin at a step preceding removal of damaged 3' termini

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7 January 2021

DNA-dependent protein kinase catalytic subunit: a relative of phosphatidylinositol 3-kinase and the ataxia telangiectasia gene product

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7 January 2021

Enhanced phosphorylation of p53 by ATM in response to DNA damage

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7 January 2021

Radioresistant DNA synthesis: an intrinsic feature of ataxia telangiectasia

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7 January 2021

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

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7 January 2021

DNA crosslinking induced by x-rays and chemical agents

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7 January 2021

Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

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7 January 2021

DNA-dependent protein kinase acts upstream of p53 in response to DNA damage

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7 January 2021

Differential etoposide sensitivity of cells deficient in the Ku and DNA-PKcs components of the DNA-dependent protein kinase

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7 January 2021

Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints

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7 January 2021

Overproduction of topoisomerase II in an ataxia telangiectasia fibroblast cell line: comparison with a topoisomerase II-overproducing hamster cell mutant

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7 January 2021

Splitting the ATM: distinct repair and checkpoint defects in ataxia–telangiectasia

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7 January 2021

10.1016/S0959-8049(99)00311-1

Identifiers

DOI

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24 September 2017

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