(Q40900661)

24 September 2017

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title

Therapeutic potential of protein kinase C inhibitors (English)

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24 September 2017

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Bradshaw D

1

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24 September 2017

Hill CH

series ordinal

2

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24 September 2017

Nixon JS

series ordinal

3

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24 September 2017

Wilkinson SE

series ordinal

4

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24 September 2017

publication date

1 January 1993

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24 September 2017

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24 September 2017

volume

38

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24 September 2017

issue

1-2

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24 September 2017

page(s)

135-147

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Molecular basis of new approaches to the therapy of rheumatoid arthritis

24 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1007%2FBF02027225

Myocyte injury and contraction abnormalities produced by cytotoxic T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02027225

Animal stroke models. They are relevant to human disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02027225

Staurosporine, a novel protein kinase C inhibitor, prevents postischemic neuronal damage in the gerbil and rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF02027225

T-cell recognition of myelin basic protein

21 January 2018

1 reference

12 December 2020

Changes in the activity of protein kinase C and the differential subcellular redistribution of its isozymes in the rat striatum during and following transient forebrain ischemia

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12 December 2020

Selective post-transcriptional down-regulation of protein kinase C isoenzymes in leukemic T cells chronically treated with phorbol ester

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12 December 2020

Response of low-passage human malignant gliomas in vitro to stimulation and selective inhibition of growth factor-mediated pathways.

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12 December 2020

Alteration of DNA topoisomerase II activity during infection of H9 cells by human immunodeficiency virus type 1 in vitro: a target for potential therapeutic agents

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12 December 2020

Human immunodeficiency virus induces phosphorylation of its cell surface receptor

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12 December 2020

Effects of a protein kinase C inhibitor (H-7) on norepinephrine release from vascular adrenergic neurons in spontaneously hypertensive rats

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12 December 2020

Is there a biochemical lesion in intrinsic asthma?

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12 December 2020

A novel conformationally restricted protein kinase C inhibitor, Ro 31-8425, inhibits human neutrophil superoxide generation by soluble, particulate and post-receptor stimuli.

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12 December 2020

Calcium modulation activates Epstein-Barr virus genome in latently infected cells

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12 December 2020

Protein kinase C is translocated to cell membranes during cerebral ischemia

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12 December 2020

The efficacy of cyclosporin A, FK-506 and prednisolone to modify the adoptive transfer of experimental allergic encephalomyelitis (EAE)

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12 December 2020

Modulation of cellular processes by H7, a non-selective inhibitor of protein kinases.

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12 December 2020

Dramatic new strategies for brain tumors emerge

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12 December 2020

Effect of tamoxifen on DNA synthesis and proliferation of human malignant glioma lines in vitro.

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12 December 2020

Effect of protein kinase C modulation on outcome of experimental CNS ischemia

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12 December 2020

Protein kinase C is required for responses to T cell receptor ligands but not to interleukin-2 in T cells

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12 December 2020

Protein kinase C and T cell activation

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12 December 2020

Alterations of phosphoinositide-specific phospholipase C and protein kinase C in the myocardium of spontaneously hypertensive rats

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12 December 2020

Further evidence for abnormal protein kinase C regulation of macromolecule secretion in fibroblasts from cystic fibrosis patients

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12 December 2020

Selective phosphorylation of human DNA methyltransferase by protein kinase C

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12 December 2020

Immunosuppressants at work

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12 December 2020

Staurosporine, a protein kinase C inhibitor interferes with proliferation of arterial smooth muscle cells

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12 December 2020

Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro

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12 December 2020

Cloning and expression of multiple protein kinase C cDNAs

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12 December 2020

Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.

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12 December 2020

1,2-Dimethylhydrazine-induced alterations in protein kinase C activity in the rat preneoplastic colon

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12 December 2020

Contractile response of spontaneously hypertensive rat caudal artery to phorbol esters

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12 December 2020

Elevated levels of diacylglycerol and decreased phorbol ester sensitivity in ras-transformed fibroblasts

1 reference

12 December 2020

Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.

1 reference

12 December 2020

Increased 19 kDa protein phosphorylation and protein kinase C activity in pressure-overload cardiac hypertrophy

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12 December 2020

Characterization and differential distribution of the three major human protein kinase C isozymes (PKC alpha, PKC beta, and PKC gamma) of the central nervous system in normal and Alzheimer's disease brains.

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12 December 2020

How to kill cancer cells: membranes and cell signaling as targets in cancer chemotherapy

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12 December 2020

Effects of tiflucarbine as a dual protein kinase C/calmodulin antagonist on proliferation of human keratinocytes and release of reactive oxygen species from human leukocytes

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12 December 2020

Protein kinase C alteration is an early biochemical marker in Alzheimer's disease

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12 December 2020

A mutant protein kinase C that can transform fibroblasts

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12 December 2020

Increased activity of 5-lipoxygenase in polymorphonuclear leukocytes from asthmatic patients

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12 December 2020

Direct and cytokine-mediated activation of protein kinase C induces human immunodeficiency virus expression in chronically infected promonocytic cells

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12 December 2020

Reduction of norepinephrine-induced tonic contraction and phosphoinositide turnover in arteries of spontaneously hypertensive rats. A possible role for protein kinase C

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12 December 2020

Transactivation of the TPA-responsive element by the oncogenic c-erbB-2 protein is partly mediated by protein kinase C

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12 December 2020

Potent selective inhibitors of protein kinase C

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12 December 2020

[The role of protein kinase C in left ventricular relaxation impaired by global ischemia]

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12 December 2020

Protein kinase C activity in normal and psoriatic cells: cultures of fibroblasts and lymphocytes

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12 December 2020

Overproduction of protein kinase C causes disordered growth control in rat fibroblasts

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12 December 2020

Decreased protein kinase C activity in psoriatic versus normal epidermis

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12 December 2020

Biological effects of cyclosporin A: A new antilymphocytic agent

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12 December 2020

Differentiation of second messenger systems in mast cell activation

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12 December 2020

Binding of [3H]inositoltrisphosphate and [3H]phorbol 12,13-dibutyrate in rat hippocampus following transient global ischemia: A quantitative autoradiographic study

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12 December 2020

Pharmacology of second messengers: a critical appraisal

1 reference

12 December 2020

Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C

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12 December 2020

Diacylglycerol formation and DNA synthesis in endothelin-stimulated rat C6 glioma cells: the possible role of phosphatidylcholine breakdown.

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12 December 2020

Immunological aspects of demyelinating diseases

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12 December 2020

Increased sensitivity to protein kinase C activation in aortas of spontaneously hypertensive rats

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12 December 2020

Decrease in phorbol ester receptors in human brain tumors

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12 December 2020

Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA.

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12 December 2020

Interleukin-2 stimulates association of protein kinase C with plasma membrane

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12 December 2020

Protein kinase C alterations in the fetal rat brain after global ischemia

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12 December 2020

Immunosuppressive effect of FK506 on experimental allergic encephalomyelitis in rats

1 reference

12 December 2020

Prolactin induces proliferation of vascular smooth muscle cells through a protein kinase C-dependent mechanism

1 reference

12 December 2020

Interleukin-2 induces proliferation of T lymphocyte mutants lacking protein kinase C

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12 December 2020

Regulation of the beta-receptor-adenylate cyclase system in lymphocytes of allergic patients with asthma: possible role for protein kinase C in allergen-induced nonspecific refractoriness of adenylate cyclase

1 reference

12 December 2020

Possible involvement of protein kinase C in platelet-derived growth factor-stimulated DNA synthesis in vascular smooth muscle cells

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12 December 2020

Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis

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12 December 2020

Reduced protein kinase C activity in ischemic spinal cord

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12 December 2020

Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways.

1 reference

12 December 2020

Altered protein kinase C activity in different subfields of hippocampus following cerebral ischemia

1 reference

12 December 2020

Mechanical loading stimulates cell hypertrophy and specific gene expression in cultured rat cardiac myocytes. Possible role of protein kinase C activation

1 reference

12 December 2020

An inducible transcription factor activates expression of human immunodeficiency virus in T cells

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12 December 2020

Antiinflammatory and antiallergic effects of a novel metabolite of Nocardiopsis sp. as a potent protein kinase C inhibitor from microbial origin

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12 December 2020

Decreased protein kinase C activity during cerebral ischemia and after reperfusion in the adult rat.

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12 December 2020

Tumor necrosis factor production by Kupffer cells requires protein kinase C activation.

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12 December 2020

Higher Na+???H+ exchange rate and more alkaline intracellular pH set-point in essential hypertension: effects of protein kinase modulation in platelets

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12 December 2020

A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro anti-proliferative as well as in vivo anti-tumor activity

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12 December 2020

The effect of new potent selective inhibitors of protein kinase C on the neutrophil respiratory burst

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12 December 2020

Inhibition of growth of established human glioma cell lines by modulators of the protein kinase-C system.

1 reference

12 December 2020

Aberrant protein phosphorylation and cytoarchitecture in Alzheimer's disease

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12 December 2020

Protein kinase C activity in erythrocytes in primary hypertension: regulation of cell shape and cation transport

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12 December 2020

Possible involvement of Ca2+ mobilization and protein kinase C activation in the induction of spontaneous metastasis by mouse mammary adenocarcinoma cells

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12 December 2020

The role of protein kinase C in cell surface signal transduction and tumour promotion

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12 December 2020

Enhanced vascular reactivity to protein kinase C activators in genetically hypertensive rats

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12 December 2020

Epstein-Barr virus internalization and infectivity are blocked by selective protein kinase C inhibitors

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12 December 2020

Protein phosphorylation during ischemia

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12 December 2020

Antitumor activity of UCN-01, a selective inhibitor of protein kinase C, in murine and human tumor models

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12 December 2020

Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements

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12 December 2020

Characterization of the hepatitis B virus preS/S region encoded transcriptional transactivator

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12 December 2020

K252a is a potent and selective inhibitor of phosphorylase kinase

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12 December 2020

The role of protein kinase C in growth control and the concept of carcinogenesis as a progressive disorder in signal transduction

1 reference

12 December 2020

Phorbol-12,13-dibutyrate-induced vasoconstriction in vivo: characterization of response in genetic hypertension

1 reference

12 December 2020

Signal transduction events in human basophils. A comparative study of the role of protein kinase C in basophils activated by anti-IgE antibody and formyl-methionyl-leucyl-phenylalanine

1 reference

12 December 2020

Novel, potent and selective inhibitors of protein kinase C show oral anti-inflammatory activity

1 reference

12 December 2020

In vitro correction of impaired Na+-K+-ATPase in diabetic nerve by protein kinase C agonists

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12 December 2020

Impaired T-cell activation in patients with systemic lupus erythematosus

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12 December 2020

Synergistic enhancement of the antiproliferative activity of cis-diamminedichloroplatinum(II) by the ether lipid analogue BM41440, an inhibitor of protein kinase C

1 reference

12 December 2020

Effects of protein kinase C inhibitors on viral entry and infectivity

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12 December 2020

Vascular responsiveness to phorbol esters in coarctation-hypertensive rats

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12 December 2020

Inhibition of Protein-Kinase C in Peripheral Blood Mononuclear Cells of Patients with Systemic Lupus Erythematosus: Effect on Spontaneous Immunoglobulin Production

1 reference

12 December 2020

Effect of staurosporine, a protein kinase C inhibitor, on impairment of working memory in rats exposed to cerebral ischemia

1 reference

12 December 2020

The X-protein of hepatitis B virus. Facts and fiction

1 reference

12 December 2020

Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy

1 reference

12 December 2020

A defect in the protein kinase C system in T cells from patients with systemic lupus erythematosus

1 reference

12 December 2020

Calcium ionophore enables soluble agonists to stimulate macrophage 5-lipoxygenase

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12 December 2020

Action of amyloid beta-protein on protein kinase C activity.

1 reference

12 December 2020

Identifiers

DOI

10.1007/BF02027225

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24 September 2017

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